OXAMFLATIN

Product Name: OXAMFLATIN
CAS No.: 151720-43-3
Chemical Name: OXAMFLATIN
Synonyms: CS-2473;Metacept 3;METACEPT 3;OXAMFLATIN;Oxamflatin (Metacept-3);(E)-N-hydroxy-5-(3-(phenylsulfonaMido)phenyl)pent-2-en-4-ynaMide;(2E)-N-Hydroxy-5-[3-[(Phenylsulfonyl)Amino]Phenyl]-2-Penten-4-Ynamide;2-Penten-4-ynamide, N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-, (2E)-
CBNumber: CB3504059
Molecular Formula: C17H14N2O4S
Formula Weight: 342.37
MOL File: 151720-43-3.mol

More

Less

OXAMFLATIN Property

Melting point:: 98-100°C
Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 13 mg/mL, soluble
form: solid
pka: 7.75±0.10(Predicted)
color: Light yellow to yellow
Stability:: Light sensitive

More

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O3139
Product name: Oxamflatin
Purity: ≥98% (HPLC), solid
Packaging: 1mg
Price: $187
Updated: 2024/03/01

Sigma-Aldrich

Product number: O3139
Product name: Oxamflatin
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $656
Updated: 2024/03/01

Cayman Chemical

Product number: 13176
Product name: Oxamflatin
Purity: ≥95%
Packaging: 1mg
Price: $77
Updated: 2024/03/01

Cayman Chemical

Product number: 13176
Product name: Oxamflatin
Purity: ≥95%
Packaging: 5mg
Price: $340
Updated: 2024/03/01

Cayman Chemical

Product number: 13176
Product name: Oxamflatin
Purity: ≥95%
Packaging: 10mg
Price: $602
Updated: 2024/03/01

More

Less

OXAMFLATIN Chemical Properties,Usage,Production

Chemical Properties

Red-Brown Solid

Uses

Histone deacetylase inhibitor. A cell-permeable, aromatic sulfonamide derivative with a hydroxamic acid group that potently inhibits mammalian HDAC by binding to the active site zinc.

Definition

ChEBI: 5-[3-(benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamide is a sulfonamide.

Enzyme inhibitor

This anti-tumor agent (FW = 342.38 g/mol; CAS 151720-43-3; Solubility: 13 mg/mL DMSO, methanol, acetonitrile, 10 mg/mL), also known as (2E)- 5-[3-[(phenylsulfonyl)amino]phenyl]-pent-2-en-4-ynohydroxamate, inhibits histone deacetylase. Oxamflatin shows antiproliferative activity in vitro against various mouse and human tumor cell lines, attended by drastic changes in the cell morphology and in vivo antitumor activity against B16 melanoma. Oxamflatin causes an elongated cell shape with filamentous protrusions as well as arrest of the cell cycle at the G1 phase in HeLa cells. These phenotypic changes in HeLa cells were similar to those induced by trichostatin A (TSA), a specific inhibitor of histone deacetylase (HDAC).

OXAMFLATIN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

OXAMFLATIN Suppliers

Canada 1 China 42 Switzerland 1 United Kingdom 1 United States 8 USA 1 Global 54

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.

Tel: 027-65388397 18164111589
Fax: 027-65388397
Email: 3321478047@qq.com
Country: China
ProdList: 1997
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: Sales@changyanchem.cn
Country: China
ProdList: 5010
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8014
Advantage: 62

More

Less

View Lastest Price from OXAMFLATIN manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Oxamflatin 151720-43-3
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2021-09-13

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Oxamflatin 151720-43-3
Price: US $100.00/Kg/Bag
Min. Order: 1KG
Purity: 99%
Supply Ability: 10kg
Release date: 2021-09-14

Career Henan Chemical Co

Product: OXAMFLATIN 151720-43-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-26

151720-43-3, OXAMFLATINRelated Search:

BML-210 Sodium Butyrate Suberohydroxamic acid 1H-Benz[de]isoquinoline-2(3H)-butanamide SCRIPTAID SPLITOMICIN Sodium 4-phenylbutyrate BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE APICIDIN CAY10603 Tubacin Entinostat HC TOXIN M344 Parthenolide 3-Ethynylaniline 3-PENTEN-1-YNE OXAMFLATIN

CS-2473

Metacept 3

METACEPT 3;OXAMFLATIN

(E)-N-hydroxy-5-(3-(phenylsulfonaMido)phenyl)pent-2-en-4-ynaMide

(2E)-N-Hydroxy-5-[3-[(Phenylsulfonyl)Amino]Phenyl]-2-Penten-4-Ynamide

Oxamflatin (Metacept-3)

2-Penten-4-ynamide, N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-, (2E)-

151720-43-3

Pharmaceuticals

Sulfur & Selenium Compounds

Antitumour

Amines

Aromatics

Inhibitors

Intermediates & Fine Chemicals