ChemicalBook > CAS DataBase List > Propargyl-PEG4-t-butyl ester

Propargyl-PEG4-t-butyl ester

Product Name: Propargyl-PEG4-t-butyl ester
CAS No.: 1355197-66-8
Chemical Name: Propargyl-PEG4-t-butyl ester
Synonyms: Propargyl-PEG4-Boc;Propargyl-PEG4-COOtBu;Alkyne-PEG4-CH2CH2COOtBu;Propargyl-PEG3-C2-COOtBu;Propargyl-PEG4-t-Bu Ester;PROPARGYL-PEG4-CH2CH2COOTBU;Propargyl-PEG4-t-butyl ester;tert-butyl 4,7,10,13-tetraoxahexadec-15-ynoate;tert-Butyl 4,7,10,13-tetraoxahexadec-15-yn-1-oate;4,7,10,13-Tetraoxahexadec-15-ynoic acid, 1,1-dimethylethyl ester
CBNumber: CB33049632
Molecular Formula: C16H28O6
Formula Weight: 316.39
MOL File: 1355197-66-8.mol

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Propargyl-PEG4-t-butyl ester Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P839553
Product name: Propargyl-Peg4-T-ButylEster
Packaging: 100mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-21093
Product name: Propargyl-PEG4-t-butylester
Purity: 98%
Packaging: 250mg
Price: $230
Updated: 2021/12/16

BroadPharm

Product number: BP-21093
Product name: Propargyl-PEG4-t-butylester
Purity: 98%
Packaging: 500mg
Price: $380
Updated: 2021/12/16

Activate Scientific

Product number: AS107917
Product name: Propargyl-PEG4-CH2CH2COOtBu
Purity: 97%
Packaging: 1g
Price: $541
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1745
Product name: Propargyl-PEG4-t-butyl ester
Packaging: 250mg
Price: $565
Updated: 2021/12/16

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Propargyl-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG4-t-butyl ester enables the formation of a stable triazole linkage with azide compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-butyl protected carboxyl group can be hydrolyzed under acidic conditions.

Uses

Propargyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Propargyl-PEG4-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG4-COOtBu 1355197-66-8
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-26

Career Henan Chemical Co

Product: Propargyl-PEG4-t-butyl ester 1355197-66-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 500kg
Release date: 2018-08-19

1355197-66-8, Propargyl-PEG4-t-butyl esterRelated Search:

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Propargyl-PEG4-t-butyl ester

Alkyne-PEG4-CH2CH2COOtBu

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Propargyl-PEG4-Boc

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1355197-66-8

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