DIHYDROMETHYSTICIN
- Product Name
- DIHYDROMETHYSTICIN
- CAS No.
- 19902-91-1
- Chemical Name
- DIHYDROMETHYSTICIN
- Synonyms
- dhm;Nsc112159;PseudoMethysticin;DIHYDROMETHYSTICIN;DIHYDROMETHYLSTICIN;7,8-dihydromethysticin;7,8-DIHYDROMETHYLSTICIN;Methysticin, 7,8-dihydro-;Dihydroanesthetic capsicin;Dihydromethysticin ((+)-Dihydromethysticin)
- CBNumber
- CB3307966
- Molecular Formula
- C15H16O5
- Formula Weight
- 276.28
- MOL File
- 19902-91-1.mol
DIHYDROMETHYSTICIN Property
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
- Boiling point:
- 476.1±45.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- Melting point:
- 117-118 °C
- color
- White to Off-White
- BRN
- 91699
- Stability:
- Hygroscopic
- InChIKey
- RSIWXFIBHXYNFM-NSHDSACASA-N
- LogP
- 1.810 (est)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 52007
- Product name
- (+)-Dihydromethysticin
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $539
- Updated
- 2022/05/15
- Product number
- 27644
- Product name
- Dihydromethysticin
- Packaging
- 5mg
- Price
- $238
- Updated
- 2024/03/01
- Product number
- B203530
- Product name
- (6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
- Packaging
- 10mg
- Price
- $375
- Updated
- 2021/12/16
- Product number
- CS-4245
- Product name
- Dihydromethysticin
- Packaging
- 10mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- HBL0000233
- Product name
- (+)-DIHYDROMETHYSTICIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $933.26
- Updated
- 2021/12/16
DIHYDROMETHYSTICIN Chemical Properties,Usage,Production
Description
Dihydromethysticin is a kavalactone originally isolated from P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.
Uses
(6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one, is used in toxicity studies through in vitro analysis. This complex is found in the roots of kava plant.
Definition
ChEBI: Dihydromethysticin is a member of 2-pyranones and an aromatic ether.
DIHYDROMETHYSTICIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DIHYDROMETHYSTICIN manufacturers
- Product
- DIHYDROMETHYSTICIN 19902-91-1
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-10