ChemicalBook > CAS DataBase List > EC 4.2.1.1

EC 4.2.1.1

Product Name
EC 4.2.1.1
CAS No.
9001-03-0
Chemical Name
EC 4.2.1.1
Synonyms
TDX-02;EC 4.2.1.1;Dehydratase;IUB: 4.2.1.1;CA, HUMAN LIVER;PANCREAS, BOVINE;CARBONIC ANHYDRASE;CARBONIC ANHYDRASE I;CARBONATE DEHYDRATASE;CARBONATE HYDRO-LYASE
CBNumber
CB3317318
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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EC 4.2.1.1 Property

RTECS 
MT6446000
storage temp. 
-20°C
solubility 
deionized water: soluble, clear to slightly hazy, colorless (Dissolve vial contents in 0.25mL of deionised water.)
form 
powder
color 
white
Water Solubility 
Soluble in water
Merck 
13,1822
Concentration
0.01 mCi/ml
Specific Activity
3-30 μCi/mg
Solvent
0.01M NaH2PO4 (pH 7.2)
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Safety

Hazard Codes 
B,Xi,T
Risk Statements 
36-41-40-37/38-24-20/22
Safety Statements 
26-45-36/37/39-53
WGK Germany 
3
F 
10-21
HS Code 
35079090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C7025
Product name
Carbonic Anhydrase from bovine erythrocytes
Purity
BioReagent, suitable for GFC marker
Packaging
1vial
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
C6653
Product name
Carbonic Anhydrase I from human erythrocytes
Purity
Isoelectric focusing marker, pI?6.6
Packaging
1vial
Price
$139
Updated
2024/03/01
Sigma-Aldrich
Product number
C5024
Product name
Carbonic Anhydrase from bovine erythrocytes
Purity
non-denaturing PAGE marker
Packaging
1vial
Price
$30.52
Updated
2024/03/01
Sigma-Aldrich
Product number
C3666
Product name
Carbonic Anhydrase Isozyme II from bovine erythrocytes
Purity
Isoelectric focusing marker, pI?5.4
Packaging
1vial
Price
$155
Updated
2024/03/01
Sigma-Aldrich
Product number
C2522
Product name
Carbonic Anhydrase Isozyme II from bovine erythrocytes
Purity
lyophilized powder, ≥3,000 W-A units/mg protein
Packaging
5mg
Price
$175
Updated
2024/03/01
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EC 4.2.1.1 Chemical Properties,Usage,Production

Uses

Carbonic anhydrase from human erythrocytes (HCA) has been used to study the molten-globule state of carbonic anhydrase (CA). Chaperone-like α-crystallin binds to this state of the enzyme and prevents its aggregation. The enzyme from sigma has been used for the analysis of thermodynamic stability of the enzyme. Furthermore, its clinical significance has been evaluated in human non-small cell lung cancer.

Uses

Gel filtration molecular weight marker

Uses

Carbonic anhydrase, from bovine erythrocytes, is used to create carbon dioxide capture systems and to research various purification techniques . Carbonic anhydrase is also used to study acid-base regulation in fish and carbonic anhydrase type II deficiency syndrome .

General Description

Carbonic Anhydrase is a metalloenzyme?with zinc. The active site of carbonic anhydrase contains three conserved histidine residues (His94, His96 and His119).

Biochem/physiol Actions

Carbonic anhydrase is essential for the reversible hydration of carbon dioxide. It is also crucial for the physiological processes including respiration, ion transport, acid–base balance, lipid and carbohydrate metabolic pathways. Carbonic anhydrase participates in electrolyte secretion and in the carbon dioxide fixation.

Purification Methods

Purify carbonic anhydrase by hydroxylapatite and DEAE-cellulose chromatography [Tiselius et al. Arch Biochem Biophys 65 132 1956, Biochim Biophys Acta 39 218 1960], and is then dialysed for crystallisation. A 0.5 to 1% solution of the enzyme in 0.05 M Tris-HCl pH 8.5 is dialysed against 1.75M solution of (NH4)2SO4 in the same buffer, and this solution is slowly increased in salt concentration by periodic removal of small amounts of dialysate and replacing with an equal volume of 3.5M (NH4)2SO4. The final salt concentration, in which the DEAE-cellulose fractions give beautiful birefringent suspensions of crystals, ranged from 2.4 to 2.7M and appeared first as fine crystals, then underwent transition to thin fragile plates. Carbonic anhydrase is a Zn enzyme which exists as several isoenzymes of varying degrees of activity [J Biol Chem 243 6474 1968, crystal structure: Nature, New Biology 235 131 1972; see also P.D. Boyer Ed. The Enzymes Academic Press NY, pp 587-665 1971].

EC 4.2.1.1 Preparation Products And Raw materials

Raw materials

Preparation Products

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EC 4.2.1.1 Suppliers

China 80 Europe 2 Germany 4 India 1 Switzerland 1 United States 12 Global 100
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Creative Enzymes
Tel
1-516-855-7709
Fax
1-631-938-8127
Email
info@creative-enzymes.com
Country
United States
ProdList
8748
Advantage
58
Creative Enzymes
Tel
--
Fax
--
Email
info@creative-enzymes.com
Country
United States
ProdList
6057
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
Crescent Chemical Co., Inc.
Tel
--
Fax
--
Email
sales@creschem.com
Country
United States
ProdList
4597
Advantage
68
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Rockland Immunochemicals Inc.
Tel
--
Fax
--
Email
info@rockland-inc.com
Country
United States
ProdList
2043
Advantage
76
Biozyme Laboratories International, Ltd.
Tel
--
Fax
--
Email
bioinfo@biozyme.com
Country
United States
ProdList
60
Advantage
59
Worthington Biochemical Corporation
Tel
--
Fax
--
Email
office@worthington-biochem.com
Country
United States
ProdList
109
Advantage
77
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View Lastest Price from EC 4.2.1.1 manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Carbonic Anhydrase, Lyophilized Powder 9001-03-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-24
Hangzhou ICH Biofarm Co., Ltd
Product
Dehydratase 9001-03-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99% HPLC
Supply Ability
100kg
Release date
2023-06-30

9001-03-0, EC 4.2.1.1Related Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE PHENYLSELENOL Tosylmethyl isocyanide METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE N-BUTYLISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) Ferric acetylacetonate Ethyl isocyanoacetate Cupric acetylacetonate Benzyl isocyanide TERT-BUTYL ISOCYANIDE MOLECULAR SIEVES

  • Dehydratase
  • CARBONIC ANHYDRASE FROM BOVINE ERYTHRO-CYTES, >2000 U/MG*
  • CARBONIC ANHYDRASE ISOZYME II, BOVINE ER YTHR., ~1800 U/MG
  • CARBONIC ANHYDRASE BOVINE ERYTHROCYTESAP PROX MOL W
  • CARBONIC ANHYDRASE, BOVINE ERYTHROCYTES FOR GEL FIL
  • CARBONIC ANHYDRASE FROM BOVINEERYTHROCYT ES FOR SDS
  • PANCREAS, BOVINE
  • Dehydratase, carbonate
  • TDX-02
  • carbonic anhydrase from bovine erythro-cytes
  • carbonic anhydrase I pi approx. 6.6
  • carbonic anhydrase ii from bovine*erythrocytes pi
  • carbonic anhydrase ii pi approx. 5.4
  • Carbonic Anhydrase Isozyme II from bovine erythrocytes
  • CARBONIC ANHYDRASE II PI APPROX. 7.4
  • CARBONIC ANHYDRASE II PI APPROX. 5.9
  • Carbonic Anhydrase I from human erythrocytes
  • CarbonicAnhydraseExBovineErythrocytes
  • Carbonic anhydrase from bovine erythrocytes ca. 1.5 U/mg
  • carbonic anhydrase isozyme ii from human erythrocytes
  • Carbonate Dehydratase, Carbonate Hydrolyase, Carbonic Anhydrase II
  • Carbonate Dehydratase, Carbonate Hydrolyase
  • Carbonic Anhydrase from bovine erythrocytes,Carbonate Dehydratase, Carbonate Hydrolyase
  • Carbonic Anhydrase [from bovine erythrocytes, 2000 units/mg]
  • Carbonic anhydrase from bovine erythrocytes, lyophil.
  • Carbonic anhydrase, lyophil.
  • Carbonic Anhydrase, Lyophilized Powder
  • Carbonic anhydrase froM bovine erythrocytes ca. 1.5 U/Mg lyophil.
  • EC 4.2.1.1
  • IUB: 4.2.1.1
  • CA, HUMAN LIVER
  • CA1, BOVINE ERYTHROCYTES
  • CARBONATE DEHYDRATASE
  • CARBONATE HYDRO-LYASE
  • CARBONIC ANHYDRASE
  • CARBONIC ANHYDRASE BOVINE ERYTHROCYTES
  • CARBONIC ANHYDRASE, HUMAN LIVER
  • CARBONIC ANHYDRASE I
  • CARBONIC ANHYDRASE I, BOVINE ERYTHROCYTES
  • CARBONIC ANHYDRASE II
  • CARBONIC ANHYDRASE ISOZYME II
  • Carbonic Anhydrase Isozyme II human
  • Carbonic Anhydrase from human erythrocytes
  • Carbonic Anhydrase Isozyme I
  • Carbonic Anhydrase II from Human, Recombinant
  • Native Human Carbonic Anhydrase
  • Native Human Carbonic Anhydrase I
  • Native Bovine Carbonic Anhydrase
  • Carbonic Anhydrase II from Bovine, Recombinant
  • 9001-03-0
  • General Metabolic Enzymes
  • Gel Filtration Chromatography
  • General Metabolic Enzymes A-H
  • Enzyme Class Index
  • Enzymes, Inhibitors, and Substrates
  • 4.2.x.x C-O bonds
  • 4.x.x.x Lyases
  • Metabolomics