ChemicalBook > CAS DataBase List > Acid-PEG6-t-butyl ester
Acid-PEG6-t-butyl ester
- Product Name
- Acid-PEG6-t-butyl ester
- CAS No.
- 2093153-84-3
- Chemical Name
- Acid-PEG6-t-butyl ester
- Synonyms
- COOH-PEG6-OtBu;Acid-PEG6-C2-Boc;COOH-PEG6-COOtBu;Acid-PEG6-t-Bu Ester;Acid-PEG6-t-butyl ester;HOOCCH2CH2O-PEG5-CH2CH2COOtBu;Carboxy-PEG6-tert-butyl Ester;4,7,10,13,16,19-Hexaoxadocosanedioic acid, 1-(1,1-dimethylethyl) ester;HOOCCH2CH2O-PEG5-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxadocosanedioic acid, 1-(1,1-dimethylethyl) ester
- CBNumber
- CB33303327
- Molecular Formula
- C20H38O10
- Formula Weight
- 438.51
- MOL File
- 2093153-84-3.mol
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Acid-PEG6-t-butyl ester Property
- Boiling point:
- 528.9±50.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23511
- Product name
- Acid-PEG6-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $980
- Updated
- 2021/12/16
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Acid-PEG6-t-butyl ester Chemical Properties,Usage,Production
Description
Acid-PEG6-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Acid-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG6-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Acid-PEG6-t-butyl ester Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
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View Lastest Price from Acid-PEG6-t-butyl ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- COOH-PEG6-COOtBu 2093153-84-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23
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