ChemicalBook > CAS DataBase List > 2,5-Dichloro-3-nitropyridine

2,5-Dichloro-3-nitropyridine

Product Name
2,5-Dichloro-3-nitropyridine
CAS No.
21427-62-3
Chemical Name
2,5-Dichloro-3-nitropyridine
Synonyms
2,5-DICHLORO-3-NITROPYRIDINE;Pyridine, 2,5-dichloro-3-nitro-;2,5-Dichloro-3-nitropyridine>2,5-Dichloro-3-nitropyridine 97%;2,5-Dichloro-3-nitropyridine ,97%;2,5-Dichloro-3-nitropyridine ISO 9001：2015 REACH
CBNumber
CB3366215
Molecular Formula
C5H2Cl2N2O2
Formula Weight
192.99
MOL File
21427-62-3.mol
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2,5-Dichloro-3-nitropyridine Property

Melting point:
41-45 °C
Boiling point:
265.3±35.0 °C(Predicted)
Density 
1.629±0.06 g/cm3(Predicted)
Flash point:
>110°(230°F)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
pka
-4.99±0.10(Predicted)
form 
Crystalline Powder and/or Chunks
color 
Light beige-green to orange
CAS DataBase Reference
21427-62-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi,T
Risk Statements 
36/37/38-22-43-41-37/38-25
Safety Statements 
36/37/39-26-45
RIDADR 
2811
WGK Germany 
1
Hazard Note 
Harmful
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
730548
Product name
2,5-Dichloro-3-nitropyridine
Purity
97%
Packaging
5g
Price
$58.2
Updated
2023/06/20
TCI Chemical
Product number
D4267
Product name
2,5-Dichloro-3-nitropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$63
Updated
2025/07/31
TCI Chemical
Product number
D4267
Product name
2,5-Dichloro-3-nitropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$236
Updated
2025/07/31
TRC
Product number
D438820
Product name
2,5-Dichloro-3-nitropyridine
Packaging
500mg
Price
$60
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
35312
Product name
2,5-Dichloro-3-nitropyridine
Purity
95+%
Packaging
5G
Price
$326
Updated
2021/12/16
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2,5-Dichloro-3-nitropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow crystalline powder

Uses

2,5-Dichloro-3-Nitropyridine has useful herbicidal properties. Furthermore, it is useful as a chemical intermediate for dyes, pharmaceutical and other agricultural applications.

Synthesis

5409-39-2

21427-62-3

(Step 1) 5-Chloro-3-nitropyridin-2-amine (10.0 g, 57.6 mmol) was dissolved in concentrated hydrochloric acid (100 mL), cooled to -10 °C and stirred continuously. An aqueous solution of sodium nitrite (9.94 g, 144 mmol) was slowly added dropwise (20 mL) over 30 min. After the dropwise addition, the reaction mixture was kept at 0 °C with continued stirring for 1 hour. Subsequently, the pH of the reaction solution was adjusted to 9 with 1N aqueous sodium hydroxide solution and then extracted with ethyl acetate. Insoluble impurities were removed by filtration and the organic layer was washed with saturated brine and dried with anhydrous magnesium sulfate. After filtration, the solvent was removed by distillation under reduced pressure to afford the target product 2,5-dichloro-3-nitropyridine (6.50 g, yield: 58.5%) as a solid.1H-NMR (CDCl3) δ: 8.60 (1H, d, J = 2.9 Hz), 8.24 (1H, d, J = 2.6 Hz).

References

[1] Patent: WO2007/67875, 2007, A2. Location in patent: Page/Page column 15
[2] Patent: JP2016/56134, 2016, A. Location in patent: Paragraph 0165; 0166; 0167
[3] Patent: JP2016/56133, 2016, A. Location in patent: Paragraph 0158; 0159
[4] Patent: EP3109239, 2016, A1. Location in patent: Paragraph 0189
[5] Journal of the Chemical Society, 1952, p. 2042,2044

2,5-Dichloro-3-nitropyridine Preparation Products And Raw materials

Raw materials

2-Amino-5-chloropyridine N,N-Dimethylformamide Toluene Nitric acid Thionyl chloride

Preparation Products

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View Lastest Price from 2,5-Dichloro-3-nitropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2,5-Dichloro-3-nitropyridine 21427-62-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-30
Hebei Chuanghai Biotechnology Co,.LTD
Product
2,5-Dichloro-3-nitropyridine 21427-62-3
Price
US $30.00-10.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100000kg
Release date
2024-08-22
Henan Fengda Chemical Co., Ltd
Product
2,5-Dichloro-3-nitropyridine 21427-62-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30

21427-62-3, 2,5-Dichloro-3-nitropyridineRelated Search:

3,5-Dichloropyridine 2-Chloro-3-hydroxypyridine Clopyralid 2-Bromo-5-nitropyridine 4-Chloro-3-nitropyridine 3-Aminopyridine 3-Hydroxypyridine 3-Nitrotoluene 2-Chloro-5-chloromethylpyridine 2,5-Dichloropyridine 2-Chloro-3-nitropyridine 3-Nitropyridine 2,4-Dichloro-3-nitropyridine 5-CHLORO-3-PYRIDINAMINE 2,5-Dichloropyridin-3-amine 3-CHLORO-5-NITROPYRIDINE 2,6-DICHLORO-3-NITRO-4-AMINOPYRIDINE 2,6-Dichloro-3-nitropyridine

  • 2,5-Dichloro-3-nitropyridine 97%
  • 2,5-DICHLORO-3-NITROPYRIDINE
  • 2,5-Dichloro-3-nitropyridine ,97%
  • 2,5-Dichloro-3-nitropyridine&gt
  • Pyridine, 2,5-dichloro-3-nitro-
  • 2,5-Dichloro-3-nitropyridine ISO 9001：2015 REACH
  • 21427-62-3
  • C5H2Cl2N2O2
  • Heterocycle-Pyridine series
  • Pyridines
  • Chlorinated heterocyclic series
  • Pyridine