5-Bromonicotinic acid

ChemicalBook > CAS DataBase List > 5-Bromonicotinic acid

5-Bromonicotinic acid

Product Name: 5-Bromonicotinic acid
CAS No.: 20826-04-4
Chemical Name: 5-Bromonicotinic acid
Synonyms: 5-BROMOPYRIDINE-3-CARBOXYLIC ACID;Nicergoline impurity D CRS;5-BROMO-3-PYRIDINECARBOXYLIC ACID;DF97;AURORA KA-3027;CAS:20826-04-4;AKOS BBS-00007710;5 - broMine niacin;TIMTEC-BB SBB003524;RARECHEM AL BO 0841
CBNumber: CB3375701
Molecular Formula: C6H4BrNO2
Formula Weight: 202.01
MOL File: 20826-04-4.mol

Less

5-Bromonicotinic acid Property

Melting point:: 178-180 °C(lit.)
Boiling point:: 259.67°C (rough estimate)
Density: 1.7477 (rough estimate)
vapor pressure: 0.01Pa at 25℃
refractive index: 1.6120 (estimate)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Powder
pka: 3.08±0.10(Predicted)
color: White to yellow-gray or light brown
BRN: 115854
InChI: InChI=1S/C6H4BrNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,(H,9,10)
InChIKey: FQIUCPGDKPXSLL-UHFFFAOYSA-N
SMILES: C1=NC=C(Br)C=C1C(O)=O
LogP: 1.17-1.29 at 23.5℃ and pH6.4
CAS DataBase Reference: 20826-04-4(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
RTECS: QT0868000
HazardClass: IRRITANT
HS Code: 29333999

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 228435
Product name: 5-Bromopyridine-3-carboxylic acid
Purity: 98%
Packaging: 10g
Price: $40.68
Updated: 2024/03/01

Sigma-Aldrich

Product number: 228435
Product name: 5-Bromopyridine-3-carboxylic acid
Purity: 98%
Packaging: 50g
Price: $59.6
Updated: 2024/03/01

TCI Chemical

Product number: B1818
Product name: 5-Bromonicotinic Acid
Purity: >99.0%(GC)(T)
Packaging: 25g
Price: $59
Updated: 2024/03/01

Alfa Aesar

Product number: A13589
Product name: 5-Bromonicotinic acid, 98%
Packaging: 5g
Price: $26.1
Updated: 2021/12/16

Alfa Aesar

Product number: A13589
Product name: 5-Bromonicotinic acid, 98%
Packaging: 25g
Price: $72.7
Updated: 2021/12/16

Less

5-Bromonicotinic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromopyridine-3-carboxylic acid (5-bromonicotinic acid) was used in the synthesis of 3-guanidinomethyl-5-iodopyridine.

Reactions

5-Bromonicotinic acid could used as starting material to synthesize 3-guanidinomethyl-5-iodopyridine. It is also used to prepare four novel multifunctional coordination compounds with different lanthanide(III) ions (Dy, Tb, Yb, and Nd). These materials possess different structures and dimensionalities and show interesting magnetic and luminescence properties, as well as a complete absence of cytotoxicity both in cancer and non-cancer Caco-2 cells[1-2].

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 2381, 1948 DOI: 10.1021/ja01187a020

Purification Methods

The acid is recrystallised from H2O and then from EtOH using charcoal. The amide has m 219-219.5o (from aqueous EtOH), and the methyl ester, prepared by addition of ethereal diazomethane, can be purified by sublimation in a vacuum and has m 98-99o. The acid chloride also can be sublimed in vacuo and has m 74-75o and gives the methyl ester in MeOH. [Graf J Prakt Chem 138 244 1933, Bachman & Micucci J Am Chem Soc 70 2381 1948, Garcia et al. J Am Chem Soc 82 4430 1960, Misic-Vokovic et al. J Chem Soc 34 1978, Beilstein 22/2 V 181.]

References

[1] Vaidyanathan G, et al. Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine. Bioconjugate Chemistry, 1998; 9: 758–764.
[2] Ruiz C, et al. Multifunctional coordination compounds based on lanthanide ions and 5-bromonicotinic acid: magnetic, luminescence and anti-cancer properties. CrystEngComm, 2019; 21: 3881-3890.

5-Bromonicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

5-Aminonicotinic acid 5-AMINO-NICOTINIC ACID METHYL ESTER 5-Fluoronicotinic acid

Less

5-Bromonicotinic acid Suppliers

Americas 1 Austria 1 Belgium 4 Canada 3 China 460 Czech Republic 1 Europe 4 France 2 Germany 11 India 60 Ireland 1 Japan 6 Slovakia 1 South Korea 2 Switzerland 4 Ukraine 2 United Kingdom 24 United States 72 Global 659

Jiangyin Jufeng Biotechnology Co., Ltd

Tel: 13906113265
Email: 986329407@qq.com
Country: China
ProdList: 45
Advantage: 58

Fama Shijiazhuang Fine Chemical Co., Ltd.

Tel: 0311-88800819 13932107110
Fax: 86-0311-85111404
Email: sales@jztchem.com
Country: China
ProdList: 14
Advantage: 62

Hubei Xinkang Pharmaceutical Chemical Co., Ltd

Tel: 027-59308705 18871579363
Fax: 027-59308705
Email: 1248180077@qq.com
Country: China
ProdList: 9949
Advantage: 58

Shanghai Taijilin Industrial Co., Ltd.

Tel: 021-021-50630626 18964684208
Fax: 021-50563898
Email: kate@tajilin.com
Country: China
ProdList: 1230
Advantage: 58

Jubilant Life Sciences(Shanghai)Ltd.

Tel: 021-63907388-21 18017369769
Email: jerry_zhang@jubl.com
Country: China
ProdList: 188
Advantage: 58

Fuxin Kaituo Fine Chemical Technology Co., Ltd

Tel: 15714082442
Email: 3757845877@qq.com
Country: China
ProdList: 346
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9413
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11655
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Shijiazhuang Dowell Chemical Co., Ltd

Tel: 0311-89805679 +86-13463963265
Fax: 0311-85262695
Email: sell@dowechem.com
Country: China
ProdList: 50
Advantage: 62

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 021-51613915-820 13611835272
Fax: 021 51613951
Email: mmwang@sunwaypharm.cn
Country: China
ProdList: 9734
Advantage: 57

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3203
Advantage: 55

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2871
Advantage: 58

Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
Fax: 022-23854368
Email: sales@jinyudachem.com
Country: China
ProdList: 1889
Advantage: 55

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5047
Advantage: 50

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9459
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Wuhan Kaymke Chemical Co., Ltd.,

Tel: 027-027-87342388 18086026008
Fax: 027-87342388
Email: sales@kaymke.com
Country: China
ProdList: 3881
Advantage: 55

Less

View Lastest Price from 5-Bromonicotinic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 5-Bromonicotinic acid 20826-04-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-19

Hebei Chuanghai Biotechnology Co,.LTD

Product: 5-Bromonicotinic acid 20826-04-4
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-15

Hebei Weibang Biotechnology Co., Ltd

Product: 5-Bromonicotinic acid 20826-04-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2021-11-18

20826-04-4, 5-Bromonicotinic acidRelated Search:

Citric acid Folic acid Isonicotinic acid EPA 5-Bromonicotinic acid ethyl ester 97%,Ethyl 5-Bromonicotinic acid ethyl ester,5-BROMONICOTINIC ACID ETHYL ESTER 5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-1H-imidazolin-2-yl)nicotinic acid Xanthinol nicotinate N,N-Dimethylpropionamide 2,2-Dimethylbutyryl chloride 2-Phenylbutyric acid 5-Bromophthalide 5-Bromoindole 5-Bromopyrimidine 5-Bromo-2-oxindole DIMETHYL 5-BROMOISOPHTHALATE Ascoric Acid Bromine 2-AMINO-5-BROMONICOTINIC ACID,2-Amino-5-bromonicotinic acid 95%,2-Amino-5-bromonicotinic acid ,97%

RARECHEM AL BO 0841

TIMTEC-BB SBB003524

AKOS BBS-00007710

3-PYRIDINECARBOXYLIC ACID, 5-BROMO-

3-BROMO-5-PYRIDINE CARBOXYLIC ACID

3-BROMO PYRIDINE-5-CARBOXYLIC ACID

5-BROMO-3-PYRIDINECARBOXYLIC ACID

5-BROMONICOTINC ACID

5-BROMONICOTINIC ACID

5-BROMOPYRIDINE-3-CARBOXYLIC ACID

5-bromo-3-pyridinecarboxylicaci

5-bromo-nicotinicaci

AURORA KA-3027

IFLAB-BB F3095-3197

5-BromonicotinicAcid98%

5-Bromo-3-pyridinecarboxylic

5-Bromonicotic acid

5-BROMOPYRIDINE-3-CARBOXYLIC ACID / 5-BROMONICOTINIC ACID

5-Bromonicotinic acid, 5-Bromopyridine-3-carboxylic acid

3-Carboxy-5-bromopyridine

5-BROMO NICOTINIC ACID 5-BROMO NICOTINIC ACID

Nicotinic acid, 5-bromo-

5- broMinenicotinic acid

5 - broMine niacin

Nicergoline impurity D

5-Bromopyridine-3-carboxylic acid, 3-Bromo-5-carboxypyridine

5-Bromopyridine-3-carboxylic acid 98%

CAS:20826-04-4

Nicergoline Impurity 4(Nicergoline EP Impurity D)

5-Bromonicotinic Acid &gt

Nicergoline impurity D CRS

Nicergoline EP Impurity D (5-Bromonicotinic acid)

Nicergoline Impurity 4

5-Bromonicotinic acid USP/EP/BP

DF97

5-Bromopyridin-3-carboxylic acid

20826-04-4

Bromopyridines

Halopyridines

Building Blocks

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyridines

Pyridines, Pyrimidines, Purines and Pteredines

pharmacetical

Heterocycles

alkyl bromide|carboxylic acid

Bromopyridines

Halopyridines

Carboxylic Acids

Pyridine series

Carboxylic Acids

Organic acids

Pyridines derivates

PROTECTED AMINO ACID & PEPTIDES

blocks

Bromides

Carboxes