β-N-AcetylglucosaMinidase

Product Name: β-N-AcetylglucosaMinidase
CAS No.: 9012-33-3
Chemical Name: β-N-AcetylglucosaMinidase
Synonyms: NAG;MPS3B;NAGLU;MPS-IIIB;EC 3.2.1.52;EC 3.2.1.30;β-N-acetylhexosaminidase;β-N-AcetylglucosaMinidase;β-N-AcetylglucosaMinidase;Acetylglucosaminidase, B2
CBNumber: CB3451584
Molecular Formula: NULL
Formula Weight: 0
MOL File: Mol file

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β-N-AcetylglucosaMinidase Property

Density: 1.37[at 20℃]
vapor pressure: 0.004Pa at 25℃
storage temp.: 2-8°C
form: lyophilized powder
color: Colorless to light yellow
Water Solubility: 125g/L at 25℃
LogP: -1.3 at 20℃

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Safety

Hazard Codes: B
Risk Statements: 20/22-24-37/38-41-42
Safety Statements: 53-26-36/37/39-45
WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2264
Product name: β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean)
Purity: ammonium sulfate suspension, ≥10?units/mg protein
Packaging: 5units
Price: $165
Updated: 2024/03/01

Sigma-Aldrich

Product number: A2264
Product name: β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean)
Purity: ammonium sulfate suspension, ≥10?units/mg protein
Packaging: 10units
Price: $302
Updated: 2024/03/01

Sigma-Aldrich

Product number: A6805
Product name: β-N-Acetylglucosaminidase from Streptococcus pneumoniae
Purity: recombinant, expressed in E. coli, buffered aqueous solution
Packaging: 1vial
Price: $639
Updated: 2024/03/01

Sigma-Aldrich

Product number: A2264
Product name: β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean)
Purity: ammonium sulfate suspension, ≥10?units/mg protein
Packaging: 25units
Price: $566
Updated: 2024/03/01

Sigma-Aldrich

Product number: 110116
Product name: β1-2,3,4,6-N-Acetylglucosaminidase,
Packaging: 1u
Price: $523
Updated: 2024/03/01

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β-N-AcetylglucosaMinidase Chemical Properties,Usage,Production

Uses

β -N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease 1 . Acetylglucosaminidase from Canavalia ensiformis has been used to study enzymic detachment of biofilms.

Uses

Bovine kidney β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer′s Disease .

Flammability and Explosibility

Not classified

Biochem/physiol Actions

β-N-Acetylglucosaminidase from Streptococcus pneumoniae is an extracellular glycosidase and has broad specificity over the β1-3 and β1-6 linkages present in mucins. It belongs to the glycoside hydrolase family 85 (GH85). Also called endo-β-N-acetylglucosaminidase, it cleaves at the asparagine residue of the di-N-acetylchitobiose structure in oligosaccharides and acts on fucosylated N-glycan core. Its deglycosylation functionality is exploited in studying functions of glycoproteins.

Purification Methods

Purify it by chromatography on DEAD-Biogel, hydroxylapatite chromatography and gel filtration through Sephacryl S200. Two isoforms: a hexosaminidase EI with Km 177WM

β-N-AcetylglucosaMinidase Preparation Products And Raw materials

Raw materials

Preparation Products

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β-N-AcetylglucosaMinidase Suppliers

China 57 Europe 3 France 1 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 6 Global 72

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Sigma-Aldrich

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Hubei HongxinRuiYu Fine Chemical Co., Ltd.

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9012-33-3, β-N-AcetylglucosaMinidaseRelated Search:

SALCOMINE Ferric acetylacetonate TERT-BUTYL ISOCYANIDE Cupric acetylacetonate Aluminum acetylacetonate Tosylmethyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Benzyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE N-BUTYLISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) PHENYLSELENOL Ethyl isocyanoacetate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE

N-ACETYL-BETA-D-GLUCOSAMINIDASE

N-ACETYL-BETA-D-GLYCOSAMINIDE-N-ACETYLGLUCOSAMINOHYDROLASE

NAG

BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE

BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, STREPTOCOCCUS PNEUMONIAE

BETA-N-ACETYLGLUCOSAMINIDASE

BETA-N-ACETYLGLUCOSAMINIDASE H

BETA-N-ACETYLHEXOSAMINIDASE

EC 3.2.1.30

EC 3.2.1.52

2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSIDE ACETAMIDODEOXYGLUCOHYDROLASE

Acetylglucosaminidase, beta-

B-N-ACETYLGLUCOSAMINIDASE FROMASPERGILLU S NIGER

B-N-ACETYLGLUCOSAMINIDASE AFROM HUMAN PL ACENTA

B-N-ACETYLGLUCOSAMINIDASE, RECOMBINANT, EXPRESSED I

B-N-ACETYLGLUCOSAMINIDASE P

B-N-ACETYLGLUCOSAMINIDASEFROM HUMAN PLAC ENTA

BETA-N-ACETYLGLUCOSAMINIDASE,JACK BEANS, ~50 U/MG, 500 UG*

B-N-ACETYLGLUCOSAMINIDASE FROM JACK BEANS

B-N-ACETYLGLUCOSAMINIDASE FROM BOVINEKID NEY

B-N-ACETYLGLUCOSAMINIDASE AFROM PORCINE PLACENTA

Acetylhexosaminidase, .beta.-

β-n-acetylglucosaminidase from bovine kidney

β-n-acetylglucosaminidase from canavalia ensiformis (jack bean)

β-n-acetylglucosaminidase from human placenta

β-n-acetylglucosaminidase from streptococcus pneumoniae

BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, S. PNEUMONIAE, RECOMBINANT

2-Acetamido-2-deoxy-β-D-glucoside acetamidodeoxyglucohydrolase

β-N-AcetylglucosaminidaseA from bovine epididymis

β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase

β-N-AcetylglucosaminidaseB from bovine epididymis

β-N-Acetylglucosaminidase preparation from Aspergillus niger

β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution

β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean),β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase, β-N-Acetylhexosaminidase

Achromopeptidase Lysobacter sp.

β-N-Acetylglucosaminidase A preparation from porcine placenta

β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution

β-N-Acetylglucosaminidase P preparation from human placenta

β-N-Acetylglucosaminidase A preparation from human placenta

MPS3B

MPS-IIIB

NAGLU

β-N-AcetylglucosaMinidase

β1-2,3,4,6-N-Acetylglucosaminidase,

β1-2,3,4,6-N-Acetylglucosaminidase, Streptococcus pneumoniae, Recombinant, E. coli

Hexosaminidase 3C from Saccharophagus degradans, Recombinant

Hexosaminidase 3A from Thermotoga neapolitana, Recombinant

Native Canavalia ensiformis β-N-Acetylglucosaminidase

Native Human β-N-Acetylglucosaminidase

Native Bovine β-N-Acetylglucosaminidase

β-N-Acetylglucosaminidase from Streptococcus pneumoniae, Recombinant

β-N-Acetylhexosaminidase from Streptococcus pyogenes, Recombinant

beta-N-Acetylglucosaminidase from Streptococcus pneumoniae

beta-N-Acetylglucosaminidase from bovine kidney

beta-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean)

β-N-acetylhexosaminidase

Acetylglucosaminidase, B2

β-N-AcetylglucosaMinidase