2-Methoxy-3-nitropyridine

Product Name: 2-Methoxy-3-nitropyridine
CAS No.: 20265-35-4
Chemical Name: 2-Methoxy-3-nitropyridine
Synonyms: 2-METHOXY-3-NITROPYRIDINE;3-Nitro-2-methoxypyridine;Pyridine, 2-methoxy-3-nitro-;2-Methoxy-3-nitropyridine>METHYL 3-NITRO-2-PYRIDINYL ETHER;2-Methoxy-3-nitropyridine ISO 9001：2015 REACH
CBNumber: CB3476383
Molecular Formula: C6H6N2O3
Formula Weight: 154.12
MOL File: 20265-35-4.mol

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2-Methoxy-3-nitropyridine Property

Melting point:: 53-55°C
Boiling point:: 247.9±20.0 °C(Predicted)
Density: 1.300±0.06 g/cm3(Predicted)
Flash point:: >110℃
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: -0?+-.0.10(Predicted)
color: White to Amber
BRN: 138199
InChI: InChI=1S/C6H6N2O3/c1-11-6-5(8(9)10)3-2-4-7-6/h2-4H,1H3
InChIKey: WZNQCVOSOCGWJG-UHFFFAOYSA-N
SMILES: C1(OC)=NC=CC=C1[N+]([O-])=O
CAS DataBase Reference: 20265-35-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22-41-37/38
Safety Statements: 26-36/37/39-22-36-39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M1395
Product name: 2-Methoxy-3-nitropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $104
Updated: 2025/07/31

TCI Chemical

Product number: M1395
Product name: 2-Methoxy-3-nitropyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $327
Updated: 2025/07/31

TRC

Product number: M219128
Product name: 2-Methoxy-3-nitropyridine
Packaging: 500mg
Price: $60
Updated: 2021/12/16

TRC

Product number: M219128
Product name: 2-Methoxy-3-nitropyridine
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 032315
Product name: 2-Methoxy-3-nitropyridine
Packaging: 5g
Price: $61
Updated: 2021/12/16

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2-Methoxy-3-nitropyridine Chemical Properties,Usage,Production

Uses

2-Methoxy-3-nitropyridine is a pyridine compound used as a reagent in chemical reactions or as an intermediate component in organic synthesis. It can be reduced to amines and then converted to N-substituted derivatives.

Preparation

2-Methoxy-3-nitropyridine can be prepared by methylation of 2-hydroxy-3-nitropyridine^[1].

Synthesis

5470-18-8

20265-35-4

Example 12 Synthesis of 2-methoxy-3-nitropyridine STR27: 2-chloro-3-nitropyridine (25 g, 0.157 mol) was suspended in methanol (300 ml), followed by addition of sodium methanolate (17 g, 0.315 mol). The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, some of the solvent was removed by distillation under reduced pressure. The remaining reaction mixture was diluted with water (1 liter) and filtered to collect the precipitate precipitated. The resulting white solid was washed with copious amounts of water and subsequently dried under vacuum to afford the target product 2-methoxy-3-nitropyridine (18.2 g, 75% yield). The structure of the product was confirmed by 1H NMR (CDCl3): δ 8.42 (dd, J = 5,2 Hz, 1H); 8.28 (dd, J = 8,2 Hz, 1H); 7.06 (dd, J = 8,5 Hz, 1H); 4.13 (s, 3H).

References

[1] GRUBER W. PYRIDINE DERIVATIVES: PART VI MALONATIONS OF SUBSTITUTED NITROPYRIDINES[J]. Canadian Journal of Chemistry, 1953. DOI:10.1139/V53-152.

2-Methoxy-3-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Methoxy-3-nitropyridine Suppliers

Americas 1 Belgium 1 China 139 Europe 3 Germany 7 Hungary 1 India 8 Japan 3 Ukraine 1 United Kingdom 10 United States 33 Global 207

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View Lastest Price from 2-Methoxy-3-nitropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Methoxy-3-nitropyridine 20265-35-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-06-29

PNP Biotech Co. Ltd

Product: 2-Methoxy-5-nitropyridine 20265-35-4
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2022-09-16

Dideu Industries Group Limited

Product: 2-Methoxy-3-nitropyridine 20265-35-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-07

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2-METHOXY-3-NITROPYRIDINE

METHYL 3-NITRO-2-PYRIDINYL ETHER

3-Nitro-2-methoxypyridine

2-Methoxy-3-nitropyridine&gt

Pyridine, 2-methoxy-3-nitro-

2-Methoxy-3-nitropyridine ISO 9001：2015 REACH

20265-35-4

20256-35-4

Pyridine

Pyridines derivates

Pyridines