Phenoxyacetic acid

ChemicalBook > CAS DataBase List > Phenoxyacetic acid

Phenoxyacetic acid

Product Name: Phenoxyacetic acid
CAS No.: 122-59-8
Chemical Name: Phenoxyacetic acid
Synonyms: Phenylium;phenoxyacetic;O-PHENYLGLYCOLIC ACID;PHENYLOXYL ACETIC ACID;2-cyclohexyloxyacetate;PHENYLIUM(R);PHENYLIUM(TM);AKOS BBS-00003724;phenoxyacetc acid;Phenxoyacetic acid
CBNumber: CB3485839
Molecular Formula: C8H8O3
Formula Weight: 152.15
MOL File: 122-59-8.mol

Less

Phenoxyacetic acid Property

Melting point:: 98-100 °C (lit.)
Boiling point:: 285 °C
Density: 1.2143 (rough estimate)
refractive index: 1.4447 (estimate)
FEMA: 2872 | PHENOXYACETIC ACID
Flash point:: 165 °C
storage temp.: Store below +30°C.
solubility: ethanol: soluble10%, clear, colorless
form: Granular Powder, Granules, or Prills
pka: 3.17(at 25℃)
color: White
Odor: at 1.00 % in propylene glycol. sour sweet
Odor Type: honey
Water Solubility: 0.1-0.5 g/100 mL at 17 ºC
Merck: 14,7254
JECFA Number: 1026
BRN: 907949
Stability:: Stable. Substances to be avoided include strong bases, strong oxidizing agents. Combustible.
InChIKey: LCPDWSOZIOUXRV-UHFFFAOYSA-N
LogP: 1.34
CAS DataBase Reference: 122-59-8(CAS DataBase Reference)
NIST Chemistry Reference: Acetic acid, phenoxy-(122-59-8)
EPA Substance Registry System: Phenoxyacetic acid (122-59-8)

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36-37/39
RIDADR: UN 3345 6.1/ PGIII
WGK Germany: 3
RTECS: AJ2230000
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29189090
Toxicity: LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 158518
Product name: Phenoxyacetic acid
Purity: 98%
Packaging: 500g
Price: $81
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.00667
Product name: Phenoxyacetic acid
Purity: for synthesis
Packaging: 500g
Price: $112
Updated: 2022/05/15

Sigma-Aldrich

Product number: 34366
Product name: Phenoxyacetic acid
Purity: PESTANAL?, analytical standard
Packaging: 100MG
Price: $43.9
Updated: 2022/05/15

TCI Chemical

Product number: P0107
Product name: Phenoxyacetic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: P0107
Product name: Phenoxyacetic Acid
Purity: >98.0%(GC)(T)
Packaging: 500g
Price: $53
Updated: 2024/03/01

Less

Phenoxyacetic acid Chemical Properties,Usage,Production

Chemical Properties

Phenoxyacetic acid has a sour, sweet odor and a honey-like taste.

Occurrence

Reported found in cocoa beans

Uses

Phenoxyacetic acid is a flavoring ingredient.?Its photodegradation using titanium dioxide as photocatalyst has been studied. Selective separation of penicillin V from phenoxyacetic acid using liquid membranes consisting of 1,2-dichloroethane and Amberlite LA-2 as carrier has been studied.

Uses

Fungicide; keratin exfoliative (to relieve and to soften calluses, corns, and other hard skin surfaces; applied as plasters, pads or in liquids).

Definition

ChEBI: Phenoxyacetic acid is a monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes. It has a role as a human xenobiotic metabolite, an Aspergillus metabolite, a plant growth retardant and an allergen. It is a monocarboxylic acid and an aromatic ether. It is functionally related to a glycolic acid. It is a conjugate acid of a phenoxyacetate.

Synthesis Reference(s)

Synthetic Communications, 16, p. 479, 1986 DOI: 10.1080/00397918608057726

General Description

Light tan powder or white solid.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Phenoxyacetic acid reacts exothermically with all bases, both organic (for example, the amines) and inorganic.

Health Hazard

ACUTE/CHRONIC HAZARDS: Phenoxyacetic acid is a mild skin irritant.

Fire Hazard

Flash point data for Phenoxyacetic acid are not available; however Phenoxyacetic acid is probably combustible.

Synthesis

A Schlenk tube was charged with aryl iodides (1) (1.0 mmol), glycolic acid (228 mg, 3.0 mmol), CuI (19.0 mg, 0.1 mmol), Cs2CO3 (1.95 g, 6.0 mmol), and DMSO/H2O (2 mL/1 mL). The mixture was stirred for 24 h at 120 ℃ under Ar. The reaction mixture was allowed to cool to room temperature, poured into 5 mL of water, and then acidified to pH = 1 with 2 N HCl solution. The aqueous phase was extracted twice with EtOAc, and the combined organic layer was washed with H2O and brine, dried over anhydrous MgSO4, and concentrated under vacuum. Purification of the crude product by column chromatography (dichloromethane/methanol) afforded the desired product Phenoxyacetic acid, white solid, yield 133 mg, 88%.

Purification Methods

Crystallise the acid from water or aqueous EtOH. [Beilstein 6 IV 634.]

Phenoxyacetic acid Preparation Products And Raw materials

Raw materials

Chloroacetic acid Phenol

Preparation Products

Allyl phenoxyacetate 4-(Hydroxymethyl)phenoxyacetic acid ?4-Chlorophenoxyacetic acid sodium salt 4-Chlorophenoxyacetic acid 2,4-Dichlorophenoxyacetic acid Benzofuran 2,4-Dichlorophenoxybutyric acid

Less

Phenoxyacetic acid Suppliers

Americas 1 Belgium 1 China 360 Europe 4 Germany 7 India 52 Japan 4 Slovakia 1 South Korea 1 Spain 1 Switzerland 2 The Netherlands 1 United Kingdom 4 United States 55 Global 494

Hebei zeshuo pharmaceutical technology co. LTD

Tel: 0319-4869289 13021800888
Email: export@zeshuobiotec.com
Country: China
ProdList: 8
Advantage: 58

Wuhan kemike Biomedical Technology Co., Ltd

Tel: 027-87747081 18186681184
Email: 1344475572@qq.com
Country: China
ProdList: 7243
Advantage: 58

Wuhan kamik Technology Co., Ltd

Tel: 18062587608
Email: 201981259@qq.com
Country: China
ProdList: 7716
Advantage: 58

HENGSHUI HAOYE CHEMICAL CO.,LTD.

Tel: 0318-2102300 18632882519
Fax: 0318-2103390
Email: hy@chemcoms.com
Country: China
ProdList: 80
Advantage: 58

Qujing Zhanyi Quanda Chemical Co., Ltd.

Tel: 13267170933
Email: 366546038@qq.com
Country: China
ProdList: 71
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

BeiJing Hwrk Chemicals Limted

Tel: 0757-86329057 18501085097
Fax: 010-89508210
Email: sales3.gd@hwrkchemical.com
Country: China
ProdList: 7583
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12458
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11660
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12990
Advantage: 57

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11714
Advantage: 57

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9664
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9725
Advantage: 55

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4974
Advantage: 50

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17779
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6139
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18216
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

Shanghai Ruji Biology Technology Co., Ltd.

Tel: +86-21-65211385-8001 36031160
Fax: +86-21-65211385-8004
Email: sales@shruji.com
Country: China
ProdList: 3224
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7876
Advantage: 55

Wuxi Zhangkun Biochemical Technology Co., Ltd.

Tel: +86 0510-85629785
Fax: +86 0510-85625359
Country: China
ProdList: 2331
Advantage: 58

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3933
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9908
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2931
Advantage: 58

Shanghai DiBai Chemicals Co., Ltd.

Tel: 021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3993
Advantage: 60

RiZhao LiDeShi Chemical Co., Ltd.

Tel: 010-51268198
Fax: 010-63833209
Email: leadershipchem@126.com
Country: China
ProdList: 2549
Advantage: 58

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 1352-6885213 15637198702
Fax: 0371-63709726
Email: xpkchem@163.com
Country: China
ProdList: 3998
Advantage: 58

Mei Lan Industrial (Shanghai) Co., Ltd.

Tel: 021-58958189
Fax: 021-58957967
Email: wouchina@126.com
Country: China
ProdList: 2671
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Shanghai ideal Industrial Co., Ltd.

Tel: 021-58957966 18930537195
Fax: 021-60899437
Email: wouchina@126.com
Country: China
ProdList: 3033
Advantage: 58

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13358
Advantage: 58

GuangTuo Chemical (Shanghai) Co., Ltd.

Tel: 021-60899189-8001 18918189673
Fax: 021-60899304
Email: gtchem@126.com
Country: China
ProdList: 2661
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5223
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15878
Advantage: 55

Less

View Lastest Price from Phenoxyacetic acid manufacturers

Ningxia Jinhua Chemical Co.,Ltd

Product: Phenoxyacetic Acid 122-59-8
Price: US $6180.00/T
Min. Order: 1T
Purity: 99%
Supply Ability: 1000 tons/Year
Release date: 2021-06-24

Yancheng Green Chemicals Co.,Ltd

Product: Phenoxyacetic Acid 122-59-8
Price: US $6180.00/T
Min. Order: 1T
Purity: 99%
Supply Ability: 1000 tons/Year
Release date: 2021-06-24

Changde Changlian Chemical Co., Ltd.

Product: Phenoxyacetic Acid 122-59-8
Price: US $6180.00/T
Min. Order: 1T
Purity: 99%
Supply Ability: 1000 tons/Year
Release date: 2021-06-24

122-59-8, Phenoxyacetic acidRelated Search:

Glycolic acid Ethyl phenylacetate Ethyl 2-(Chlorosulfonyl)acetate Fluroxypyr PHENYL VALERATE Ethylbenzene Diphenyl ether Folic acid Stearic acid Phenyl salicylate Citric acid Hyaluronic acid 4-Hydroxyphenylacetic acid 2-Hydroxyphenylacetic acid Triclopyr 4-Chlorophenoxyacetic acid PHENYL RESIN Ascoric Acid Phenoxyacetic

Phenoxymethylpenicillin EP Impurity B

Phenoxymethylpenicillin Impurity 2（Phenoxymethylpenicillin EP Impurity B）

2-cyclohexyloxyacetate

Glycolic acid phenyl ether

FEMA 2872

RARECHEM AL BO 0458

O-PHENYLGLYCOLIC ACID

PHENYLOXYL ACETIC ACID

PHENYLIUM(TM)

PHENYLIUM(R)

AKOS BBS-00003724

Phenoxyacetic acid ,99%

Phenylium

Phenoxyacetic acid,Glycolic acid phenyl ether

A328 Phenoxyacetic acid

Phenoxyacetic acid, 98+% 100GR

Phenoxyacetic acid, 98+% 5GR

PHENYL ETHER GLYCOLIC ACID

PHENOXYETHANOIC ACID

PHENOXYACETIC ACID

Aceticacid, 2-phenoxy-

Acide phenoxyacetique

acidephenoxyacetique

Glycollic acid phenyl ether

glycollicacidphenylether

phenoxyacetic

Phenxoyacetic acid

PHENOXYACETIC ACID FREE ACID

PHENOXYACETIC ACID 98+%

Phenoxyacetic acid, purum

PHENOXYACETIC ACID 99%

PHENOXYACETIC ACIDPHENOXYACETIC ACID FOR SYNTHESIS GLYCOLIC ACID PHENYL ETHER

PhenoxyaceticAcidForSynthesis

Acetic acid, phenoxy-

PHENOXYACETICACID,REAGENT

Phenoxyisisnoic acid

PHENOXYACETIC ACID extrapure

phenoxyacetc acid

PhenoxyaceticAcid&gt

2-Phenoxyacetic acid,>99%

2-(2-((4-aminophenyl)amino)ethoxy)acetic acid

PHENOXYACETIC ACID MM USP/EP/BP

Phenoxyacetic acid USP/EP/BP

Phenoxyacetic acidQ: What is Phenoxyacetic acid Q: What is the CAS Number of Phenoxyacetic acid Q: What is the storage condition of Phenoxyacetic acid

122-59-8 Phenoxyacetic acid

Phenoxyacetic acid Daminozide

Phenoxyethanoic

Phenoxymethylpenicillin Potassium EP Impurity B

Phenoxymethylpenicillin EP Impurity B Glycolic acid phenyl ether

122-59-8

122-59-6

C6H5OCH2COOH

C8C8O3

C6H5OCH2CO2H

Carboxylic Acids

Carbonyl Compounds

Building Blocks