ChemicalBook > CAS DataBase List > Phenoxyacetic acid

Phenoxyacetic acid

Product Name
Phenoxyacetic acid
CAS No.
122-59-8
Chemical Name
Phenoxyacetic acid
Synonyms
Phenylium;phenoxyacetic;O-PHENYLGLYCOLIC ACID;PHENYLOXYL ACETIC ACID;2-cyclohexyloxyacetate;PHENYLIUM(R);PHENYLIUM(TM);AKOS BBS-00003724;phenoxyacetc acid;Phenxoyacetic acid
CBNumber
CB3485839
Molecular Formula
C8H8O3
Formula Weight
152.15
MOL File
122-59-8.mol
More
Less

Phenoxyacetic acid Property

Melting point:
98-100 °C (lit.)
Boiling point:
285 °C
Density 
1.2143 (rough estimate)
bulk density
500kg/m3
refractive index 
1.4447 (estimate)
FEMA 
2872 | PHENOXYACETIC ACID
Flash point:
165 °C
storage temp. 
Store below +30°C.
solubility 
ethanol: soluble10%, clear, colorless
form 
Granular Powder, Granules, or Prills
pka
3.17(at 25℃)
color 
White
Odor
at 1.00 % in propylene glycol. sour sweet
Odor Type
honey
Water Solubility 
0.1-0.5 g/100 mL at 17 ºC
Merck 
14,7254
JECFA Number
1026
BRN 
907949
Stability:
Stable. Substances to be avoided include strong bases, strong oxidizing agents. Combustible.
InChIKey
LCPDWSOZIOUXRV-UHFFFAOYSA-N
LogP
1.34
CAS DataBase Reference
122-59-8(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, phenoxy-(122-59-8)
EPA Substance Registry System
Phenoxyacetic acid (122-59-8)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36-37/39
RIDADR 
UN 3345 6.1/ PGIII
WGK Germany 
3
RTECS 
AJ2230000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29189090
Toxicity
LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rabbit > 5000 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
158518
Product name
Phenoxyacetic acid
Purity
98%
Packaging
500g
Price
$81
Updated
2024/03/01
Sigma-Aldrich
Product number
8.00667
Product name
Phenoxyacetic acid
Purity
for synthesis
Packaging
500g
Price
$112
Updated
2022/05/15
Sigma-Aldrich
Product number
34366
Product name
Phenoxyacetic acid
Purity
PESTANAL?, analytical standard
Packaging
100MG
Price
$43.9
Updated
2022/05/15
TCI Chemical
Product number
P0107
Product name
Phenoxyacetic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
P0107
Product name
Phenoxyacetic Acid
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$53
Updated
2024/03/01
More
Less

Phenoxyacetic acid Chemical Properties,Usage,Production

Chemical Properties

Phenoxyacetic acid has a sour, sweet odor and a honey-like taste.

Occurrence

Reported found in cocoa beans

Uses

Phenoxyacetic acid is a flavoring ingredient.?Its photodegradation using titanium dioxide as photocatalyst has been studied. Selective separation of penicillin V from phenoxyacetic acid using liquid membranes consisting of 1,2-dichloroethane and Amberlite LA-2 as carrier has been studied.

Uses

Fungicide; keratin exfoliative (to relieve and to soften calluses, corns, and other hard skin surfaces; applied as plasters, pads or in liquids).

Definition

ChEBI: Phenoxyacetic acid is a monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes. It has a role as a human xenobiotic metabolite, an Aspergillus metabolite, a plant growth retardant and an allergen. It is a monocarboxylic acid and an aromatic ether. It is functionally related to a glycolic acid. It is a conjugate acid of a phenoxyacetate.

Synthesis Reference(s)

Synthetic Communications, 16, p. 479, 1986 DOI: 10.1080/00397918608057726

General Description

Light tan powder or white solid.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Phenoxyacetic acid reacts exothermically with all bases, both organic (for example, the amines) and inorganic.

Health Hazard

ACUTE/CHRONIC HAZARDS: Phenoxyacetic acid is a mild skin irritant.

Fire Hazard

Flash point data for Phenoxyacetic acid are not available; however Phenoxyacetic acid is probably combustible.

Synthesis

A Schlenk tube was charged with aryl iodides (1) (1.0 mmol), glycolic acid (228 mg, 3.0 mmol), CuI (19.0 mg, 0.1 mmol), Cs2CO3 (1.95 g, 6.0 mmol), and DMSO/H2O (2 mL/1 mL). The mixture was stirred for 24 h at 120 ℃ under Ar. The reaction mixture was allowed to cool to room temperature, poured into 5 mL of water, and then acidified to pH = 1 with 2 N HCl solution. The aqueous phase was extracted twice with EtOAc, and the combined organic layer was washed with H2O and brine, dried over anhydrous MgSO4, and concentrated under vacuum. Purification of the crude product by column chromatography (dichloromethane/methanol) afforded the desired product Phenoxyacetic acid, white solid, yield 133 mg, 88%. 

Purification Methods

Crystallise the acid from water or aqueous EtOH. [Beilstein 6 IV 634.]

Phenoxyacetic acid Preparation Products And Raw materials

Raw materials

Chloroacetic acid Phenol

Preparation Products

Allyl phenoxyacetate 4-(Hydroxymethyl)phenoxyacetic acid ?4-Chlorophenoxyacetic acid sodium salt 4-Chlorophenoxyacetic acid 2,4-Dichlorophenoxyacetic acid Benzofuran 2,4-Dichlorophenoxybutyric acid
More
Less

Phenoxyacetic acid Suppliers

Americas 1 Belgium 1 China 377 Europe 4 Germany 7 India 51 Japan 4 Slovakia 1 South Korea 1 Spain 1 Switzerland 2 The Netherlands 1 United Kingdom 4 United States 56 Global 511
Hebei zeshuo pharmaceutical technology co. LTD
Tel
0319-4869289 13021800888
Email
export@zeshuobiotec.com
Country
China
ProdList
12
Advantage
58
Wuhan kemike Biomedical Technology Co., Ltd
Tel
027-87747081 18186681184
Email
1344475572@qq.com
Country
China
ProdList
7235
Advantage
58
Wuhan kamik Technology Co., Ltd
Tel
18062587608
Email
201981259@qq.com
Country
China
ProdList
7665
Advantage
58
HENGSHUI HAOYE CHEMICAL CO.,LTD.
Tel
+86-0318-2102300 +86-18632882519
Fax
0318-2103390
Email
hy@chemcoms.com
Country
China
ProdList
83
Advantage
58
Qujing Zhanyi Quanda Chemical Co., Ltd.
Tel
13267170933
Email
366546038@qq.com
Country
China
ProdList
72
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9371
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12386
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8835
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5047
Advantage
50
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9893
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Country
China
ProdList
2930
Advantage
58
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2546
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-13526885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3980
Advantage
58
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2666
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18097
Advantage
56
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
3027
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2656
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
More
Less

View Lastest Price from Phenoxyacetic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Phenoxyacetic acid 122-59-8
Price
US $65.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-06-06
Ningxia Jinhua Chemical Co.,Ltd
Product
Phenoxyacetic Acid 122-59-8
Price
US $6180.00/T
Min. Order
1T
Purity
99%
Supply Ability
1000 tons/Year
Release date
2021-06-24
Yancheng Green Chemicals Co.,Ltd
Product
Phenoxyacetic Acid 122-59-8
Price
US $6180.00/T
Min. Order
1T
Purity
99%
Supply Ability
1000 tons/Year
Release date
2021-06-24

122-59-8, Phenoxyacetic acidRelated Search:

Glycolic acid Ethyl phenylacetate Ethyl 2-(Chlorosulfonyl)acetate Fluroxypyr PHENYL VALERATE Ethylbenzene Diphenyl ether Folic acid Stearic acid Phenyl salicylate Citric acid Hyaluronic acid 4-Hydroxyphenylacetic acid 2-Hydroxyphenylacetic acid Triclopyr 4-Chlorophenoxyacetic acid PHENYL RESIN Ascoric Acid Phenoxyacetic

  • Phenoxymethylpenicillin EP Impurity B
  • Phenoxymethylpenicillin Impurity 2（Phenoxymethylpenicillin EP Impurity B）
  • 2-cyclohexyloxyacetate
  • Glycolic acid phenyl ether
  • FEMA 2872
  • RARECHEM AL BO 0458
  • O-PHENYLGLYCOLIC ACID
  • PHENYLOXYL ACETIC ACID
  • PHENYLIUM(TM)
  • PHENYLIUM(R)
  • AKOS BBS-00003724
  • Phenoxyacetic acid ,99%
  • Phenylium
  • Phenoxyacetic acid,Glycolic acid phenyl ether
  • A328 Phenoxyacetic acid
  • Phenoxyacetic acid, 98+% 100GR
  • Phenoxyacetic acid, 98+% 5GR
  • PHENYL ETHER GLYCOLIC ACID
  • PHENOXYETHANOIC ACID
  • PHENOXYACETIC ACID
  • Aceticacid, 2-phenoxy-
  • Acide phenoxyacetique
  • acidephenoxyacetique
  • Glycollic acid phenyl ether
  • glycollicacidphenylether
  • phenoxyacetic
  • Phenxoyacetic acid
  • PHENOXYACETIC ACID FREE ACID
  • PHENOXYACETIC ACID 98+%
  • Phenoxyacetic acid, purum
  • PHENOXYACETIC ACID 99%
  • PHENOXYACETIC ACIDPHENOXYACETIC ACID FOR SYNTHESIS GLYCOLIC ACID PHENYL ETHER
  • PhenoxyaceticAcidForSynthesis
  • Acetic acid, phenoxy-
  • PHENOXYACETICACID,REAGENT
  • Phenoxyisisnoic acid
  • PHENOXYACETIC ACID extrapure
  • phenoxyacetc acid
  • PhenoxyaceticAcid&gt
  • 2-Phenoxyacetic acid,>99%
  • 2-(2-((4-aminophenyl)amino)ethoxy)acetic acid
  • PHENOXYACETIC ACID MM USP/EP/BP
  • Phenoxyacetic acid USP/EP/BP
  • Phenoxyacetic acidQ: What is Phenoxyacetic acid Q: What is the CAS Number of Phenoxyacetic acid Q: What is the storage condition of Phenoxyacetic acid
  • 122-59-8 Phenoxyacetic acid
  • Phenoxyacetic acid Daminozide
  • Phenoxyethanoic
  • Phenoxymethylpenicillin Potassium EP Impurity B
  • C16045000 PhenoxyacetiCacid
  • Phenoxymethylpenicillin EP Impurity B Glycolic acid phenyl ether
  • 122-59-8
  • 122-59-6
  • C6H5OCH2COOH
  • C8C8O3
  • C6H5OCH2CO2H
  • Carboxylic Acids
  • Carbonyl Compounds
  • C8