2-BROMO-3-FORMYLPYRIDINE

Uses

Product Name: 2-BROMO-3-FORMYLPYRIDINE
CAS No.: 128071-75-0
Chemical Name: 2-BROMO-3-FORMYLPYRIDINE
Synonyms: 2-BROMONICOTINALDEHYDE;CAS:128071-75-0;2-Bromopyridine-3-ca;2-BROMO-3-FORMYLPYRIDINE;2-Bromonicotinaldehyde 97%;2-Bromonicotinaldehyde >2-broMopyridin-3-carbaldehyde;-Bromopyridine-3-carbaldehyde;2-bromopyridine-3-formaldehyde;2-Bromo-3-pyridinecarbaldehyde
CBNumber: CB3710744
Molecular Formula: C6H4BrNO
Formula Weight: 186.01
MOL File: 128071-75-0.mol

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2-BROMO-3-FORMYLPYRIDINE Property

Melting point:: 73 °C
Boiling point:: 100 °C / 3mmHg
Density: 1.683±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: -1.01±0.10(Predicted)
color: White to Orange to Green
InChI: InChI=1S/C6H4BrNO/c7-6-5(4-9)2-1-3-8-6/h1-4H
InChIKey: GNFWMEFWZWXLIN-UHFFFAOYSA-N
SMILES: C1(Br)=NC=CC=C1C=O
CAS DataBase Reference: 128071-75-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36-43
Safety Statements: 26-36/37
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 632147
Product name: 2-Bromo-3-pyridinecarboxaldehyde
Purity: 96%
Packaging: 1g
Price: $26.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 632147
Product name: 2-Bromo-3-pyridinecarboxaldehyde
Purity: 96%
Packaging: 5g
Price: $37.62
Updated: 2025/07/31

TCI Chemical

Product number: B2625
Product name: 2-Bromonicotinaldehyde
Purity: >98.0%(GC)
Packaging: 1g
Price: $32
Updated: 2025/07/31

TCI Chemical

Product number: B2625
Product name: 2-Bromonicotinaldehyde
Purity: >98.0%(GC)
Packaging: 5g
Price: $106
Updated: 2025/07/31

TRC

Product number: B677835
Product name: 2-Bromonicotinaldehyde
Packaging: 10mg
Price: $45
Updated: 2021/12/16

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2-BROMO-3-FORMYLPYRIDINE Chemical Properties,Usage,Production

Uses

2-Bromo-3-pyridinecarboxaldehyde is a pyridine heterocyclic compound mainly used in laboratory organic synthesis processes.

Chemical Properties

Yellow solid

Synthesis

109-04-6

68-12-2

128071-75-0

To a cooled solution of diisopropylamine (20.4 g, 28.0 mL, 0.202 mol) in anhydrous THF (400 mL) at -78 °C was slowly added n-BuLi (0.192 mol, 58.0 mL, 3.3 M hexane solution). The reaction mixture was stirred at -78 °C for 1 h, followed by the dropwise addition of anhydrous THF (150 mL) solution of 2-bromopyridine (25.3 g, 0.160 mol) over 20 min. After keeping the reaction at -78 °C for 90 min, an anhydrous THF (25 mL) solution of DMF (35.0 g, 0.480 mol) cooled to -78 °C was quickly added. Stirring was continued at -78 °C for 80 min, and upon completion of the reaction, the reaction was quenched with NaH2PO4 (27.6 g, 0.230 mol, dissolved in H2O (120 mL)), slowly warmed to room temperature, and diluted with MeOt-Bu (500 mL). The organic phase was separated, washed with brine (2100 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was ground with pentane and after decantation, the remaining solid was recrystallized from hexane to give 16.7 g of 2-bromo-3-pyridinecarboxaldehyde as a pale yellow solid in 56% yield, melting point 67-69 °C. 1H NMR (400 MHz, CDCl3) δ: 10.35 (s, 1H), 8.57 (dd, J=4.7,2.1 Hz, 1H), 8.17 (dd, J= 7.6,2.1Hz, 1H), 7.44 (dd, J=7.6,4.7,0.6Hz, 1H).13C NMR (101MHz, CDCl3) δ: 190.4,154.0,144.9,137.5,130.1,123.0. Calculated values for elemental analyses (C6H4BrNO): C, 38.74; H. 2.17; N, 7.53; Br, 42.96. Measured values: C, 38.58; H, 2.08; N, 7.57; Br, 42.69.

References

[1] Tetrahedron Letters, 2008, vol. 49, # 17, p. 2839 - 2843
[2] Chemical Communications, 2011, vol. 47, # 23, p. 6635 - 6637
[3] Organic Letters, 2007, vol. 9, # 5, p. 891 - 894
[4] Tetrahedron Letters, 2017, vol. 58, # 20, p. 1989 - 1991
[5] Synthesis (Germany), 2018, vol. 50, # 1, p. 155 - 169

2-BROMO-3-FORMYLPYRIDINE Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide 2-Bromopyridine Sodium borohydride Tetrahydrofuran Ammonium chloride Isopropylamine n-Butyllithium

Preparation Products

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2-BROMO-3-FORMYLPYRIDINE Suppliers

Americas 1 Belgium 2 Canada 1 China 187 Europe 1 France 2 Germany 4 India 11 Japan 1 Russia 1 Slovakia 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 10 United States 46 Global 271

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View Lastest Price from 2-BROMO-3-FORMYLPYRIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-BROMO-3-FORMYLPYRIDINE 128071-75-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-03

Henan Aochuang Chemical Co.,Ltd.

Product: 2-BROMO-3-FORMYLPYRIDINE 128071-75-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Henan Fengda Chemical Co., Ltd

Product: 2-BROMO-3-FORMYLPYRIDINE 128071-75-0
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

128071-75-0, 2-BROMO-3-FORMYLPYRIDINERelated Search:

2-BROMO-5-NITRONICOTINIC ACID 2-BROMONICOTINAMIDE 3-Acetyl-2-bromopyridine 2-BROMO-6-TRUFLUOROMETHYL-3-PYRIDINECARBOXYLIC ACID 2-BROMO-3-FORMYLPYRIDINE 2-Bromonicotinic acid 2,5-DIBROMONICOTINIC ACID 2-Bromo-5-chloronicotinic acid 2-BROMONICOTINIC ACID ETHYL ESTER 2,5-DIBROMONICOTINALDEHYDE 3,5-Dibromopyridine-4-carboxaldehyde 6-BROMO-2-FORMYLPYRIDINE,2-BROMO-6-FORMYLPYRIDINE 5-BROMO-2-FORMYLPYRIDINE,2-FORMYL-5-BROMOPYRIDINE / 5-BROMO-2-FORMYLPYRIDINE,5-Bromo-2-formylpyridine, 5-Bromo-2-picolinaldehyde 2-BROMO-4-FORMYLPYRIDINE 3-BROMO-4-FORMYLPYRIDINE 2-BROMO-5-FORMYLPYRIDINE,2-BROMO-5-FORMYLPYRIDINE97+% ,5-Dihydro-5-methyl-6-[4-(4-oxo-1(4H)-pyridinyl)phenyl]-1,2,4-triazin-3(2H)-one 5-Bromo-3-formylpyridine

2-BROMONICOTINALDEHYDE

2-BROMO-PYRIDINE-3-CARBALDEHYDE

2-BROMOPYRIDINE-3-CARBOXALDEHYDE

2-BROMO-3-FORMYLPYRIDINE

2-BROMO-3-PYRIDINECARBOXALDEHYDE

2-Bromo-3-pyridinecarboxaldehyde ,96%

2-Bromopyridine-3-carboxaldehyde 97%

2-Bromopyridine-3-carboxaldehyde, 2-Bromo-3-formylpyridine

2-Bromo-3-pyridinecarboxaldehyde,2-Bromo-3-formylpyridine

2-Bromonicotinaldehyde 97%

2-bromonicotinaldehyde(SALTDATA: FREE)

2-broMopyridin-3-carbaldehyde

2-Bromo-3-pyridinecarboxaldehyde 96%

2-Bromopyridine-3-ca

2-Bromonicotinaldehyde &gt

3-Pyridinecarboxaldehyde, 2-bromo-

2-BROMO-3-FORMYLPYRIDINE ISO 9001：2015 REACH

-Bromopyridine-3-carbaldehyde

2-bromopyridine-3-formaldehyde

2-Bromo-3-pyridinecarbaldehyde

CAS:128071-75-0

128071-75-0

Halogenated Heterocycles

Bromopyridines

Halopyridines

Pyridines

Heterocyclic Building Blocks

Building Blocks

Heterocycle-Pyridine series

Heterocycles

Halogenated

Organohalides

Bromopyridines

Halopyridines

pharmacetical

Aldehydes

Pyridines

Pyridine

Pyridines derivates