ChemicalBook > CAS DataBase List > Pyrroloquinoline quinone disodium salt

Pyrroloquinoline quinone disodium salt

Product Name
Pyrroloquinoline quinone disodium salt
CAS No.
122628-50-6
Chemical Name
Pyrroloquinoline quinone disodium salt
Synonyms
PQQ;PQQ Disodium Salt;pyrroloquinoline quineone;METHOXATIN DISODIUM SALT;disodium pyrroloquinolinedione tricarboxylate;PYRROLOQUINOLINE QUINONE DISODIUM SALTPYRROLOQUINOLINE QUINONE DISODIUM SALT;disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylat;PQQ-2Na;PQQ disodium;Methoxatin Disodium
CBNumber
CB3728738
Molecular Formula
C14H4N2Na2O8
Formula Weight
374.17
MOL File
122628-50-6.mol
More
Less

Pyrroloquinoline quinone disodium salt Property

storage temp. 
2-8°C
form 
Solid
color 
Pink to red
biological source
fermentation/recombinant
Water Solubility 
Water : 6.16 mg/mL (16.46 mM)
InChI
InChI=1S/C14H6N2O8.Na.H/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;
InChIKey
UFVBOGYDCJNLPM-UHFFFAOYSA-L
SMILES
C(C1C=C(C(=O)O)N=C2C(=O)C(=O)C3C=C(C(=O)O)NC=3C=12)(=O)O.[NaH]
More
Less

Safety

WGK Germany 
3
RTECS 
UY9454762
10-21
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
80198
Product name
Methoxatin disodium salt
Purity
≥97.0% (HPLC)
Packaging
10mg
Price
$276
Updated
2024/03/01
Sigma-Aldrich
Product number
80198
Product name
Methoxatin disodium salt
Purity
≥97.0% (HPLC)
Packaging
50mg
Price
$1130
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CHM0156690
Product name
METHOXATIN DISODIUM SALT
Purity
95.00%
Packaging
50MG
Price
$1250.35
Updated
2021/12/16
Chem-Impex
Product number
42112
Product name
Methoxatindisodiumsalt,≥97%(HPLC)
Purity
≥97%(HPLC)
Packaging
10MG
Price
$231.8
Updated
2021/12/16
ChemScene
Product number
CS-5599
Product name
Pyrroloquinolinequinonedisodiumsalt
Purity
>98.0%
Packaging
50mg
Price
$560
Updated
2021/12/16
More
Less

Pyrroloquinoline quinone disodium salt Chemical Properties,Usage,Production

Description

Pyrroloquinoline quinone disodium salt is a water-soluble quinone compound that has a strong antioxidant capacity. This product is a reddish-brown colored powder. It is isolated from cultures of methylotrophic bacteria and tissues of mammals. This essential nutrient is vital for mammals, playing a crucial role in enhancing immune function.

Uses

Pyrroloquinoline quinone disodium salt can act as an antioxidant and there is strong evidence that PQQ may play an important role in important pathways of cell signaling. PQQ plays a variety of physiological roles, such as promoting growth and reproduction and providing neurological and cardiovascular protection.

Application

Pyrroloquinoline quinone disodium salt protects cells from oxidative damage and increases the mitochondrial membrane potential, which is essential for the production of ATP. It also stimulates enzyme activities, such as glutathione peroxidase and glutathione reductase, and prevents lipid peroxidation of human serum. This compound also inhibits radiation-induced cellular damage by preventing DNA strand breakage. It may be effective in treating diseases related to oxidative stress, such as diabetes and cancer.

benefits

1.Antioxidant. PQQ (pyrroloquinoline quinone) is an antioxidant and based on research, it shows to be more powerful at fighting free radicals than vitamin C. Antioxidants work better together, so it is unclear if taking PQQ alone as a supplement can help stop any diseases.
2.Mitochondrial dysfunction. Mitochondrial disease is a group of disorders caused by mitochondrial dysfunction. One study tested PQQ supplements in men who did aerobic exercise for 6 weeks. It increased mitochondria by affecting certain proteins during exercise. Another study showed that dietary PQQ raised mitochondria activity.
3.Anti-diabetes. Problems with mitochondria are part of what causes diabetes. Animal data shows that PQQ supplements fix mitochondrial problems from diabetes and make diabetic mice respond better to insulin. Yet, there isn’t any evidence that PQQ can help people with diabetes.
4.Inflammation. PQQ might lower inflammation by lowering the C-reactive protein, interleukin-6, and other markers in your blood.
5.Nootropic. Substances that help memory, attention, and learning are sometimes called nootropics. Studies show that PQQ raises blood flow to the cerebral cortex. This supplement also may also memory problems in older people. Sleep and mood. PQQ might help with better and longer sleep. By easing fatigue, it might also help to improve moods.

Source

Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.

Biochem/physiol Actions

In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.

Side effects

From Self-Hacked: Anecdotally, some people have reported mild headaches and insomnia – usually either if too much is taken or if someone is very sensitive to the effects of supplements.
From Dr. Axe: The most commonly reported pyrroloquinoline quinone side effects include headaches, drowsiness and fatigue. Extremely high doses can also be dangerous and have actually been associated with some serious and potentially life-threatening effects on health.
keep.health/pqq-pyrroloquinoline-quinone/

Pyrroloquinoline quinone disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Pyrroloquinoline quinone disodium salt Suppliers

CHEMICAL LAND21
Tel
--
Fax
--
Email
sales21@chemicalland21.com
Country
South Korea
ProdList
6303
Advantage
74
More
Less

View Lastest Price from Pyrroloquinoline quinone disodium salt manufacturers

Jinan Million Pharmaceutical Co., Ltd
Product
Pyrroloquinoline quinone disodium salt 122628-50-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200KG
Release date
2024-04-29
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Pyrroloquinoline Quinone Disodium Salt 122628-50-6
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-06
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Pyrroloquinoline quinone disodium salt 122628-50-6
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-12-12

122628-50-6, Pyrroloquinoline quinone disodium saltRelated Search:


  • disodium4,5-dihydro-4,5-dioxo-1h-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylat
  • PQQ, Pyrrolo-quinoline-quinone disodium salt
  • sodiuM 9-carboxy-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7-dicarboxylate
  • PQQ disodium
  • 1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylicacid, 4,5-dihydro-4,5-dioxo-, sodium salt
  • PYRROLOQUINOLINE QUINONE DISODIUM SALTPYRROLOQUINOLINE QUINONE DISODIUM SALT
  • PQQ Disodium Salt
  • PYRROLOQUINOLINE QUINONE DISODIUM SALT
  • PQQ
  • METHOXATIN DISODIUM SALT
  • 3-f)quinoline-2,7,9-tricarboxylicacid,4,5-dihydro-4,5-dioxo-1h-pyrrolo(di
  • 1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylicacid
  • Methoxatin Disodium
  • Pyrroloquinoline Quinone Disodium Salt 122628-50-6
  • DISODIUM 2-CARBOXY-4,5-DIOXO-1H-PYRROLO[2,3-F]QUINOLINE-7,9-DICARBOXYLATE
  • Pyrroloquinoline Quinine Disodium Salt
  • Pyrroloquinoline quinone sodium salt
  • PYROLOQUINOLINE QUINONE DISODIUM SALT
  • Pyrroloquinoline Quinone Disodium (PQQ Disodium)
  • 1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylicacid, 4,5-dihydro-4,5-dioxo-, sodium salt (1:2)
  • Methoxatin disodium salt >=97.0% (HPLC)
  • Pyrroloquinoline quinone(PQQ) disodium salt
  • PQQ DISODIUM SALT PQQ
  • Methoxatindisodiumsal
  • Pyrrolloquinoline Quinone Disodium Salt
  • Pyrroquinoline benzoquinone sodium salt
  • PQQ (Pyrroloquinoline quinone)
  • Pyrroloquinoline Quinone Disodium Salt(PQQ)
  • Pyrroloquinoline Quinone Disodium Salt Powder
  • pyrroloquinoline quineone
  • disodium pyrroloquinolinedione tricarboxylate
  • PQQ (Methoxatin disodium salt)
  • 4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid disodium salt
  • Pyrroloquinoline Benzoquinone Sodium Salt
  • PQQ Disodium Salt>99%
  • PQQ-2Na
  • Pyrroloquinoline quinone sodium salt (PQQ)
  • Pyrroliquinoline quinone sodium salt
  • 122628-50-6
  • C14H4N2O82Na
  • C14H4N2Na2O8
  • Biochemicals and Reagents
  • BioChemical
  • Enzymes, Inhibitors, and Substrates
  • Cofactors
  • Oxidation-Reduction
  • PQQ
  • 122628-50-6
  • nutrition supplement