4-METHYL-PYRIDINE-2-CARBOXYLIC ACID

Product Name: 4-METHYL-PYRIDINE-2-CARBOXYLIC ACID
CAS No.: 4021-08-3
Chemical Name: 4-METHYL-PYRIDINE-2-CARBOXYLIC ACID
Synonyms: 4-METHYLPICOLINIC ACID;RARECHEM AL BO 2389;4-Methylpicolinicaci;4-Methylpicolinic acid ,97%;2-Formic acid-4-methylpyridine;2-carboxylic acid-4-methylpyridine;4-METHYL-PYRIDINE-2-CARBOXYLIC ACID;2-Pyridinecarboxylic acid, 4-methyl-;4-Methylpyridine-2-carboxylic acid 97%;4-Methylpyridine-2-carboxylic acid ,97%
CBNumber: CB1246887
Molecular Formula: C7H7NO2
Formula Weight: 137.14
MOL File: 4021-08-3.mol

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4-METHYL-PYRIDINE-2-CARBOXYLIC ACID Property

Melting point:: 137-141 °C
Boiling point:: 307.4±22.0 °C(Predicted)
Density: 1.230±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 1.11±0.50(Predicted)
color: White to Light yellow
CAS DataBase Reference: 4021-08-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39-24/25
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 679682
Product name: 4-Methylpyridine-2-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $228
Updated: 2023/06/20

TCI Chemical

Product number: M2758
Product name: 4-Methylpyridine-2-carboxylic Acid
Packaging: 1G
Price: $140
Updated: 2025/07/31

TRC

Product number: M339705
Product name: 4-Methylpyridine-2-carboxylic acid
Packaging: 1g
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: OR6256
Product name: 4-Methylpyridine-2-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $35
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-2U
Product name: 4-Methylpyridine-2-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $39
Updated: 2021/12/16

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4-METHYL-PYRIDINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Uses

4-Methylpyridine-2-carboxylic acid is a used in biological studies for the mutasynthesis of potential neuroprotectant derivatives of the bipyridyl collismycin A.

Synthesis

1620-76-4

4021-08-3

General procedure for the synthesis of 4-methylpyridine-2-carboxylic acid from 2-cyano-4-methylpyridine: 2-cyano-4-methylpyridine (0.15 g, 1.27 mmol) was dissolved in about 10 mL of 6 M hydrochloric acid and heated and refluxed for 24 hours. During the reaction, the solution gradually changed from the initial pale yellow color to clear. Upon completion of the reaction, the solution was evaporated to dryness to give a white solid product. Purification by recrystallization from a minimal amount of distilled water resulted in 148 mg (85% yield) of 4-methylpyridine-2-carboxylic acid. The product was characterized by 1H NMR (DMSO-d6): δ = 8.65 (1H, s), 8.06 (1H, s), 7.66 (1H, s), 2.05 (3H, s).

References

[1] Patent: WO2008/17855, 2008, A1. Location in patent: Page/Page column 49
[2] Patent: WO2008/17855, 2008, A1. Location in patent: Page/Page column 49
[3] Patent: US5219847, 1993, A
[4] Advanced Synthesis and Catalysis, 2013, vol. 355, # 5, p. 947 - 956
[5] Patent: US6251919, 2001, B1

4-METHYL-PYRIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Trimethylsilyl cyanide 4-Methylpyridine Hydrogen peroxide Sodium sulfate 3-Chloroperoxybenzoic acid Potassium carbonate Ethyl acetate Hydrochloric acid Dimethylcarbamoyl chloride Dichloromethane Acetic acid Sodium hydroxide PETROLEUM ETHER POTASSIUM CYANIDE Dimethyl sulfate

Preparation Products

Argatroban

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4-METHYL-PYRIDINE-2-CARBOXYLIC ACID Suppliers

Canada 1 China 108 Europe 3 Germany 4 India 4 Japan 1 Switzerland 1 United Kingdom 6 United States 22 Global 150

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View Lastest Price from 4-METHYL-PYRIDINE-2-CARBOXYLIC ACID manufacturers

Dideu Industries Group Limited

Product: 4-METHYL-PYRIDINE-2-CARBOXYLIC ACID 4021-08-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-METHYL-PYRIDINE-2-CARBOXYLIC ACID 4021-08-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

4021-08-3, 4-METHYL-PYRIDINE-2-CARBOXYLIC ACIDRelated Search:

2,4-DIETHYLPYRIDINE DICARBOXYLATE THIOSTREPTON 2,4-Pyridinedicarboxylic acid 5-CHLORO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID Pyrroloquinoline quinone Streptonigrin 3-[(4-CHLOROPHENYL)METHYL]-PYRIDINE-4-CARBOXYLIC ACID 6-methyl-pyridine-2-carboxylic acid ethyl ester 4-Pyridoxic acid 6-METHYL PYRIDINE-2-CARBOXYLIC ACID HCL 5-BROMO-4-METHYL-PYRIDINE-2-CARBOXYLIC ACID 6-METHYL PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER 2-FLUORO-3-METHYL-PYRIDINE-5-CARBOXYLIC ACID 2-Methylisonicotinic acid 5-BROMO-3-METHYL-PYRIDINE-2-CARBOXYLIC ACID PYRIDINE-2,4-DICARBOXYLIC ACID MONOHYDRATE Pyrroloquinoline quinone disodium salt PYRIDINE-2,4-DICARBOXYLIC ACID, [2-CARBOXYL-14C]

4-METHYLPICOLINIC ACID

4-METHYL-PYRIDINE-2-CARBOXYLIC ACID

4-Methylpyridine-2-carboxylic acid 97%

4-Methylpicolinic acid ,97%

4-Methylpyridine-2-carboxylic acid ,97%

4-Methylpicolinic acid, 2-Carboxy-4-methylpyridine

2-Pyridinecarboxylic acid, 4-methyl-

RARECHEM AL BO 2389

4-Methylpicolinicaci

4-Methy4-Methylpyridine-2-carboxylic acidlpyridine-2-carboxylic acid

4-METHYL-PYRIDINE-2-CARBOXYLIC ACID ISO 9001：2015 REACH

2-carboxylic acid-4-methylpyridine

2-Formic acid-4-methylpyridine

4021-08-3

Heterocyclic Building Blocks

Pyridines

Building Blocks

C7 and C8

Carboxylic Acids

C7 and C8

Heterocyclic Building Blocks

Heterocyclic Compounds

pharmacetical

Pyridine series

Carboxylic Acids

Pyridines