ChemicalBook > CAS DataBase List > 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE

Product Name
1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
CAS No.
154471-65-5
Chemical Name
1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
Synonyms
1-methyl-3-trifluoromethylpyrazol;1-Methyl-3-(trifluoroMethyl)pyrazole;1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE;1H-Pyrazole, 1-methyl-3-(trifluoromethyl)-;1-Methyl-3-trifluoromethyl-1H-pyrazole ,97%
CBNumber
CB3759512
Molecular Formula
C5H5F3N2
Formula Weight
150.1
MOL File
154471-65-5.mol
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1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Property

Boiling point:
137.7±35.0 °C(Predicted)
Density 
1.32g/ml
storage temp. 
2-8°C
pka
-0.71±0.10(Predicted)
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C5H5F3N2/c1-10-3-2-4(9-10)5(6,7)8/h2-3H,1H3
InChIKey
MQSLINQSJFALSP-UHFFFAOYSA-N
SMILES
N1(C)C=CC(C(F)(F)F)=N1
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Safety

Safety Statements 
22-24/25
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
M332173
Product name
1-Methyl-3-(trifluoromethyl)-1H-pyrazole
Packaging
500mg
Price
$65
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0016506
Product name
1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
Purity
95.00%
Packaging
250MG
Price
$146.06
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK135649
Product name
1-Methyl-3-trifluoromethyl-1H-pyrazole
Purity
97%
Packaging
1g
Price
$149
Updated
2021/12/16
Apolloscientific
Product number
PC31708
Product name
1-Methyl-3-(trifluoromethyl)-1H-pyrazole
Packaging
1g
Price
$151
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-3-U9
Product name
1-Methyl-3-(trifluoromethyl)-1H-pyrazole
Packaging
1g
Price
$167
Updated
2021/12/16
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1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Synthesis

59938-06-6

60-34-4

153085-15-5

154471-65-5

(E)-1-ethoxy-3-trifluoromethyl-1,3-butadiene (ETFBO, 270 g, 1.61 mol, 1.00 eq.) was dissolved in methanol (750 mL). The resulting solution was cooled in an ice-water bath, followed by the slow dropwise addition of methylhydrazine (88.3 mL, 77.7 g, 1.69 mol, 1.05 eq.) over 20 min. The reaction mixture was heated to 55 °C and stirred in dry air (via a drying tube) at this temperature for 20 hours. Upon completion of the reaction, the solvent was removed by rotary evaporation and the residue was subjected to decompression distillation: the first fraction was collected at 150 mbar, bath temperature of 130 °C, and collection temperature of 73-85 °C to give 129 g of the mixture of isomers, and the second fraction was collected at 70 mbar, bath temperature of 150 °C, and collection temperature of 75-85 °C to give 24 g of 1 -methyl-3-trifluoromethyl-1H-pyrazole. the total yield was 153 g (1.02 mol), 63% yield.

References

[1] Patent: EP2662359, 2013, A1. Location in patent: Page/Page column 6; 10

1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Preparation Products And Raw materials

Raw materials

n-Butyl vinyl ether Ethyl vinyl ether Trifluoroacetic acid Trifluoroacetic anhydride Diethyl ether Dichloromethane Methylhydrazine Methanol Pyridine 4-Dimethylaminopyridine

Preparation Products

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1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE Suppliers

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Pure Chemistry Scientific Inc.
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View Lastest Price from 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE manufacturers

Career Henan Chemical Co
Product
1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE 154471-65-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-02

154471-65-5, 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLERelated Search:

2-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]-THIOPHENE-5-CARBOXALDEHYDE 5-HYDROXY-1-METHYL-3-TRIFLUOROMETHYL-1H-PYRAZOLE 2-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]-THIOPHENE-5-CARBOXYLIC ACID 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXALDEHYDE 3-Hydroxy-1-methyl-5-trifluoromethyl-1H-pyrazole, 99+%,5-HYDROXY-2-METHYL-3-TRIFLUOROMETHYL-1H-PYRAZOLE (3-(Trifluoromethyl)-1-methyl-1H-pyrazol-4-yl)methanamine hydrochloride ,97% (5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE 3-(Trifluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide ,98% Penthiopyrad 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 2-METHYL-5-TRIFLUOROMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACID 2-[1-METHYL-5-(TRIFLUOROMETHYL)PYRAZOL-3-YL]-THIOPHENE-5-SULFONYL CHLORIDE 5-[1-METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-5-YL]THIOPHENE2-SULFONYL CHLORIDE 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-SULFONYL CHLORIDE 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE 3-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-AMINE ETHYL 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE

  • 1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE
  • 1-Methyl-3-trifluoromethyl-1H-pyrazole ,97%
  • 1-Methyl-3-(trifluoroMethyl)pyrazole
  • 1H-Pyrazole, 1-methyl-3-(trifluoromethyl)-
  • 1-methyl-3-trifluoromethylpyrazol
  • 154471-65-5
  • C5H5F3N2
  • C5H5F3N