ChemicalBook > CAS DataBase List > 11-Aminoundecanoic acid

11-Aminoundecanoic acid

Product Name
11-Aminoundecanoic acid
CAS No.
2432-99-7
Chemical Name
11-Aminoundecanoic acid
Synonyms
nci-c50613;H-11-Aun-OH;NH2-(CH2)10-COOH;ω-aminoundecanoic;11-Aminoundecansure;aminoundecanoicacid;11-Aminoundecanoic a;11-Amino-undecansaeure;11-amino-undecanoicaci;11-AMINOUNDECYLIC ACID
CBNumber
CB4187611
Molecular Formula
C11H23NO2
Formula Weight
201.31
MOL File
2432-99-7.mol
More
Less

11-Aminoundecanoic acid Property

Melting point:
188-191 °C (lit.)
Boiling point:
339.24°C (rough estimate)
Density 
0.9896 (rough estimate)
refractive index 
1.4420 (estimate)
storage temp. 
Store below +30°C.
solubility 
2g/l
pka
4.78±0.10(Predicted)
form 
Crystalline Powder
color 
White
Water Solubility 
2 g/L (20 ºC)
BRN 
1767291
InChIKey
GUOSQNAUYHMCRU-UHFFFAOYSA-N
LogP
-0.16 at 20℃
CAS DataBase Reference
2432-99-7(CAS DataBase Reference)
IARC
3 (Vol. 39, Sup 7) 1987
EPA Substance Registry System
11-Aminoundecanoic acid (2432-99-7)
More
Less

Safety

Risk Statements 
52
Safety Statements 
24/25
WGK Germany 
1
RTECS 
YQ2293000
HS Code 
29224995
Hazardous Substances Data
2432-99-7(Hazardous Substances Data)
Toxicity
LDLo orl-rat: 14,700 mg/kg NTPTR* NTP-TR-216,82
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A82605
Product name
11-Aminoundecanoic acid
Purity
97%
Packaging
100g
Price
$67.4
Updated
2024/03/01
Sigma-Aldrich
Product number
A82605
Product name
11-Aminoundecanoic acid
Purity
97%
Packaging
500g
Price
$212
Updated
2024/03/01
Sigma-Aldrich
Product number
8.01228
Product name
11-Aminoundecanoic acid
Purity
for synthesis
Packaging
250g
Price
$171
Updated
2024/03/01
TRC
Product number
A633210
Product name
11-Aminoundecanoic acid
Packaging
250g
Price
$185
Updated
2021/12/16
TRC
Product number
A633210
Product name
11-Aminoundecanoic acid
Packaging
1000g
Price
$580
Updated
2021/12/16
More
Less

11-Aminoundecanoic acid Chemical Properties,Usage,Production

Description

Aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Aminoundecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.

Chemical Properties

White crystalline powder

Chemical Properties

11-Aminoundecanoic acid is a solid.

Uses

11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1''as matrix metalloproteinase inhibitors.

Definition

ChEBI: 11-Aminoundecanoic acid is a medium-chain fatty acid.

Preparation

|?-Aminoundecanoic acid is normally prepared from castor oil (glycerol triricinoleate). Firstly the castor oil is subjected to methanolysis to yield the methyl ester of ricinoleic acid and then the following route is used:


In the first step, the pyrolysis of methyl ricinoleate is carried out at about 500??C; the principal products are n-heptaldehyde and methyl undecylenate. The latter is hydrolysed to give undecylenic acid which is treated with hydrogen bromide in a non-polar solvent in the presence of a peroxide. Under these conditions, reverse Markownikoff addition occurs and the main product is |?-bromoundecanoic acid. This product is then treated with ammonia to give |?-aminoundecanoic acid, which is a crystalline solid, m.p. 189??C.

General Description

White crystalline solid or powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

11-Aminoundecanoic acid is incompatible with strong oxidizing agents, strong acids and strong bases.

Fire Hazard

Flash point data for 11-Aminoundecanoic acid are not available; however, 11-Aminoundecanoic acid is probably combustible.

Flammability and Explosibility

Non flammable

Safety Profile

Poison by ingestion. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

11-Aminoundecanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

11-Aminoundecanoic acid Suppliers

Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel
0523-86132544 15366717810
Fax
0523-86201489
Email
sales@thbiochem.com
Country
China
ProdList
359
Advantage
55
YangZhou Ruihong Biotech Co., Ltd.
Tel
015380367604 15380367604
Fax
0514-83828236
Country
China
ProdList
510
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Dr. J. Pharmachem (India)
Tel
+91 20 24332987
Fax
+91 20 24332137
Email
info@jpharmachem.com
Country
India
ProdList
97
Advantage
55
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
More
Less

View Lastest Price from 11-Aminoundecanoic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
11-Aminoundecanoic acid 2432-99-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg
Release date
2021-09-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
11-Aminoundecanoic acid 97% 2432-99-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
11-Aminoundecanoic acid 2432-99-7
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-07

2432-99-7, 11-Aminoundecanoic acidRelated Search:


  • 11-AMINOUNDECANOIC ACID
  • 11-AMINOUNDECYLIC ACID
  • 11-amino-undecanoicaci
  • 11-AMINOUNDECANOIC ACID FOR SYNTHESIS
  • 11-amino-n-undecanoic acid
  • 11-Amino-undecansaeure
  • 11-Aminoundecanoic acid≥ 99% (Titration)
  • NH2-(CH2)10-COOH
  • OMEGA-AMINOUNDECANOIC ACID
  • OMEGA-AMINOUNDECYLIC ACID
  • 11-Aminoundecanoic aCld
  • 11-aminoundecanoicacid(11-aa)
  • Undecanoic acid, 11-amino-
  • 11-Aminoundecansure
  • aminoundecanoicacid
  • nci-c50613
  • ω-aminoundecanoic
  • 11-Aminoundecanoic acid,97%
  • H-11-Aun-OH
  • 11-Aminoundecanoic a
  • 11-AMinoundecanoic acid 11-AMinoundecanoic acid
  • 11-AMinoundecanoic acid, 97% 100GR
  • 11-AMINOUNDECANOIC ACID PURUM 98%
  • 11-Aminoundecanoic acid USP/EP/BP
  • 2432-99-7 11-Aminoundecanoic acid
  • 2432-99-7
  • 2434-99-7
  • NH2CH210CO2H
  • AMINE
  • Peptide Synthesis
  • Linear Core Amino Acids
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Linear Core Amino Acids
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives