11-Aminoundecanoic acid
- Product Name
- 11-Aminoundecanoic acid
- CAS No.
- 2432-99-7
- Chemical Name
- 11-Aminoundecanoic acid
- Synonyms
- nci-c50613;H-11-Aun-OH;NH2-(CH2)10-COOH;ω-aminoundecanoic;11-Aminoundecansure;aminoundecanoicacid;11-Aminoundecanoic a;11-Amino-undecansaeure;11-amino-undecanoicaci;11-AMINOUNDECYLIC ACID
- CBNumber
- CB4187611
- Molecular Formula
- C11H23NO2
- Formula Weight
- 201.31
- MOL File
- 2432-99-7.mol
11-Aminoundecanoic acid Property
- Melting point:
- 188-191 °C (lit.)
- Boiling point:
- 339.24°C (rough estimate)
- Density
- 0.9896 (rough estimate)
- refractive index
- 1.4420 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- 2g/l
- form
- Crystalline Powder
- pka
- 4.78±0.10(Predicted)
- color
- White
- Water Solubility
- 2 g/L (20 ºC)
- BRN
- 1767291
- InChIKey
- GUOSQNAUYHMCRU-UHFFFAOYSA-N
- LogP
- -0.16 at 20℃
- CAS DataBase Reference
- 2432-99-7(CAS DataBase Reference)
- IARC
- 3 (Vol. 39, Sup 7) 1987
- EPA Substance Registry System
- 11-Aminoundecanoic acid (2432-99-7)
Safety
- Risk Statements
- 52
- Safety Statements
- 24/25
- WGK Germany
- 1
- RTECS
- YQ2293000
- HS Code
- 29224995
- Hazardous Substances Data
- 2432-99-7(Hazardous Substances Data)
- Toxicity
- LDLo orl-rat: 14,700 mg/kg NTPTR* NTP-TR-216,82
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A82605
- Product name
- 11-Aminoundecanoic acid
- Purity
- 97%
- Packaging
- 100g
- Price
- $67.4
- Updated
- 2024/03/01
- Product number
- A82605
- Product name
- 11-Aminoundecanoic acid
- Purity
- 97%
- Packaging
- 500g
- Price
- $212
- Updated
- 2024/03/01
- Product number
- 8.01228
- Product name
- 11-Aminoundecanoic acid
- Purity
- for synthesis
- Packaging
- 250g
- Price
- $171
- Updated
- 2024/03/01
- Product number
- A633210
- Product name
- 11-Aminoundecanoic acid
- Packaging
- 250g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- A633210
- Product name
- 11-Aminoundecanoic acid
- Packaging
- 1000g
- Price
- $580
- Updated
- 2021/12/16
11-Aminoundecanoic acid Chemical Properties,Usage,Production
Description
Aminoundecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Aminoundecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
Chemical Properties
White crystalline powder
Chemical Properties
11-Aminoundecanoic acid is a solid.
Uses
11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1''as matrix metalloproteinase inhibitors.
Definition
ChEBI: 11-Aminoundecanoic acid is a medium-chain fatty acid.
Preparation
|?-Aminoundecanoic acid is normally prepared from castor oil (glycerol
triricinoleate). Firstly the castor oil is subjected to methanolysis to yield the
methyl ester of ricinoleic acid and then the following route is used:
In the first step, the pyrolysis of methyl ricinoleate is carried out at about 500??C; the principal products are n-heptaldehyde and methyl undecylenate. The latter is hydrolysed to give undecylenic acid which is treated with hydrogen bromide in a non-polar solvent in the presence of a peroxide. Under these conditions, reverse Markownikoff addition occurs and the main product is |?-bromoundecanoic acid. This product is then treated with ammonia to give |?-aminoundecanoic acid, which is a crystalline solid, m.p. 189??C.
General Description
White crystalline solid or powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
11-Aminoundecanoic acid is incompatible with strong oxidizing agents, strong acids and strong bases.
Fire Hazard
Flash point data for 11-Aminoundecanoic acid are not available; however, 11-Aminoundecanoic acid is probably combustible.
Flammability and Explosibility
Non flammable
Safety Profile
Poison by ingestion. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.
11-Aminoundecanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 11-Aminoundecanoic acid manufacturers
- Product
- 11-Aminoundecanoic acid 2432-99-7
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 1000kg
- Release date
- 2021-09-01
- Product
- 11-Aminoundecanoic acid 97% 2432-99-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 11-Aminoundecanoic acid 2432-99-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07