ChemicalBook > CAS DataBase List > H2N-PEG6-tBu

H2N-PEG6-tBu

Product Name
H2N-PEG6-tBu
CAS No.
1286281-32-0
Chemical Name
H2N-PEG6-tBu
Synonyms
tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate;H2N-PEG6-CH2CH2COOtBu;NH2-PEG6-Boc;H2N-PEG6-tBu;Amino-PEG6-COOtBu;NH2-PEG7-CH2COOtBu;NH2-PEG6-C2-COOtBu;NH2-PEG6-CH2CH2COOtBu;Amino-PEG6-t-Bu Ester;Amino-PEG7-t-butyl ester
CBNumber
CB42546870
Molecular Formula
C19H39NO8
Formula Weight
409.51
MOL File
1286281-32-0.mol
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H2N-PEG6-tBu Property

Boiling point:
475.9±40.0 °C(Predicted)
Density 
1.056±0.06 g/cm3(Predicted)
storage temp. 
-20°C
form 
Oil
pka
8.74±0.10(Predicted)
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
902659
Product name
Amino-PEG6-t-butyl ester
Packaging
250MG
Price
$195
Updated
2023/06/20
Sigma-Aldrich
Product number
902659
Product name
Amino-PEG6-t-butyl ester
Packaging
1G
Price
$714
Updated
2023/06/20
TRC
Product number
A615298
Product name
Amino-PEG6-t-butylEster
Packaging
100mg
Price
$110
Updated
2021/12/16
dPEG
Product number
10061
Product name
Amino-dPEG®₆-t-butylester
Packaging
100mg
Price
$135
Updated
2021/12/16
ChemPep
Product number
280404
Product name
H2N-PEG6-tBu
Packaging
1g
Price
$270
Updated
2021/12/16
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H2N-PEG6-tBu Chemical Properties,Usage,Production

Description

Amino-PEG6-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

H2N-PEG6-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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H2N-PEG6-tBu Suppliers

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View Lastest Price from H2N-PEG6-tBu manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG6-COOtBu 1286281-32-0
Price
US $0.00/mg
Min. Order
250mg
Purity
>98.00%
Supply Ability
250mg
Release date
2024-03-22

1286281-32-0, H2N-PEG6-tBuRelated Search:

TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA- HS-PEG10-tBu HO-PEG5-tBu H2N-PEG2-tBu N3-PEG6-tBu H2N-PEG4-tBu Azido-PEG12-azide N3-PEG4-tBu H2N-PEG8-tBu 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE Amino-PEG8-azide AMINO-PEG12-T-BUTYL ESTER 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine 20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine N3-PEG3-tBu HO-PEG1-tBu HS-PEG4-tBu H2N-PEG12-tBu

  • H2N-PEG6-tBu
  • Amino-PEG6-COOtBu
  • Amino-PEG6-t-butyl ester
  • Amino-PEG7-t-butyl ester
  • H2N-PEG6-CH2CH2COOtBu
  • NH2-PEG6-CH2CH2COOtBu
  • H2N-PEG6-CH2CH2-t-butylester
  • NH2-PEG6-Boc
  • tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate
  • Amino-PEG6-t-butylester,H2N-PEG6-t-butyl ester
  • 4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-amino-, 1,1-dimethylethyl ester
  • t-Butyl 3-Amino(peg6)propionate
  • Amino-dPEG??-t-butyl ester
  • NH2-PEG7-CH2COOtBu
  • NH2-PEG6-C2-COOtBu
  • Amino-PEG6-t-Bu Ester
  • H2N-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-amino-, 1,1-dimethylethyl ester
  • NH-2-PEG6-Boc,inhibit,ADC Linkers,Antibody-drug conjugates linkers,PROTAC Linkers,Inhibitor,NH2PEG6Boc,NH2 PEG6 Boc
  • tert-butyl 3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • 1286281-32-0
  • C19H39NO8
  • PEGylated Carboxylate
  • peg