Synthesis methods Uses
ChemicalBook > CAS DataBase List > 1-Bromo-4-iodobenzene

1-Bromo-4-iodobenzene

Synthesis methods Uses
Product Name
1-Bromo-4-iodobenzene
CAS No.
589-87-7
Chemical Name
1-Bromo-4-iodobenzene
Synonyms
P-BROMOIODOBENZENE;4-BROMOIODOBENZENE;4-BroMoiodoben;p-Bromiodobenzene;4-IODOBROMOBENZENE;p-Iodobromobenzene;4- Bromiodobenzene;1-Brom-4-iodbenzol;1-BROMO-IODOBENZENE;4-Bromophenyl iodide
CBNumber
CB4266086
Molecular Formula
C6H4BrI
Formula Weight
282.9
MOL File
589-87-7.mol
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1-Bromo-4-iodobenzene Property

Melting point:
89-91 °C(lit.)
Boiling point:
120-122 °C14 mm Hg(lit.)
Density 
2.2236 (rough estimate)
refractive index 
1.6618 (estimate)
Flash point:
120-122°C/14mm
storage temp. 
Store below +30°C.
solubility 
0.008g/l
form 
Crystalline Powder, Crystals or Needles
color 
White to brown
Water Solubility 
Insoluble in water.
Sensitive 
Light Sensitive
BRN 
1904545
InChIKey
UCCUXODGPMAHRL-UHFFFAOYSA-N
CAS DataBase Reference
589-87-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-bromo-4-iodo-(589-87-7)
EPA Substance Registry System
Benzene, 1-bromo-4-iodo- (589-87-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
Hazard Note 
Harmful/Light Sensitive
TSCA 
T
HazardClass 
IRRITANT, LIGHT SENSITIVE, IRRITANT-HARMFUL
HS Code 
29036990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
238090
Product name
1-Bromo-4-iodobenzene
Purity
98%
Packaging
5g
Price
$30.1
Updated
2024/03/01
Sigma-Aldrich
Product number
238090
Product name
1-Bromo-4-iodobenzene
Purity
98%
Packaging
25g
Price
$143
Updated
2024/03/01
TCI Chemical
Product number
B0604
Product name
1-Bromo-4-iodobenzene
Packaging
25G
Price
$71
Updated
2024/03/01
TCI Chemical
Product number
B0604
Product name
1-Bromo-4-iodobenzene
Packaging
250G
Price
$425
Updated
2024/03/01
Alfa Aesar
Product number
A13859
Product name
1-Bromo-4-iodobenzene, 98%
Packaging
10g
Price
$53.3
Updated
2024/03/01
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1-Bromo-4-iodobenzene Chemical Properties,Usage,Production

Synthesis methods

Industrial parabromoaniline is as raw material, by diazotization, iodo-synthesis of bromo iodobenzene. Preferred synthesis conditions: firstly 0.02mol parabromoaniline is dissolved in a mass fraction of 20% sulfuric acid medium, then reacts with 0.021molNaNO2 to generate bromophenyl diazonium sulfate at-10℃, and then chloroform and 0.021molKI is added into solution to process iodination reaction, after simple treatment bromo-iodobenzene crude product (which the bromo-iodobenzene HPLC purity 98.4%) is obtained, total yield after purification is 80%, increases by 15% than before improved. The product processes structural characterization by IR and 1HNMR. The improved method can greatly improve the purity of the crude product, this avoids the trouble of going through the column, this method is safe and easy to operate, easy to control the process, cost is lower, it is more suitable for the preparation of 1-Bromo-4-iodobenzene.
Unit: Heilongjiang University of Chemistry and Materials Science
Author: Guo Jing Bai Xuefeng Lvhong Fei

Uses

1. 1-Bromo-4-iodobenzene is used for organic synthesis.
2. Used as substrate for copper-free Sonogashira coupling reaction in aqueous acetone.
3. For the synthesis of β,β-dibromostyrene.

Chemical Properties

white to brown cryst. powder, crystals or needles

Uses

suzuki reaction

Uses

1-Bromo-4-iodobenzene has been employed:

  • as reagent for in situ desilylation and coupling of silylated alkynes
  • as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)
  • as substrate in copper-free Sonogashira coupling in aqueous acetone
  • in synthesis of β,β,dibromostyrenes

General Description

Vapour pressure as a function of temperature for 1-bromo-4-iodobenzene has been studied using a diaphragm manometer and torsion mass-loss effusion.

1-Bromo-4-iodobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-METHYL 3-(4-BROMOPHENYL)ACRYLATE
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1-Bromo-4-iodobenzene Suppliers

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View Lastest Price from 1-Bromo-4-iodobenzene manufacturers

Speranza Chemical Co., Ltd.
Product
1-Bromo-4-iodobenzene 589-87-7
Price
US $25.00/KG
Min. Order
1KG
Purity
98%+
Supply Ability
300MT/year
Release date
2019-12-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
1-Bromo-4-iodobenzene 589-87-7
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Hebei Weibang Biotechnology Co., Ltd
Product
1-Bromo-4-iodobenzene 589-87-7
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-06-10

589-87-7, 1-Bromo-4-iodobenzeneRelated Search:

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  • 589-87-7
  • C6H4BrI
  • ARYL HALIDE
  • Organic Building Blocks
  • Halogenated Hydrocarbons
  • Building Blocks
  • Aryl
  • C6
  • Building Blocks
  • Chemical Synthesis
  • Halogenated Hydrocarbons
  • Organic Building Blocks
  • alkyl Iodine|alkyl bromide
  • Halogenated benzene series
  • Miscellaneous
  • Benzene derivates
  • Bromine Compounds
  • Iodine Compounds
  • Light yellow crystalline powder
  • Aryl
  • C6
  • Halogenated Hydrocarbons