Propargyl-PEG1-t-butyl ester
- Product Name
- Propargyl-PEG1-t-butyl ester
- CAS No.
- 488150-84-1
- Chemical Name
- Propargyl-PEG1-t-butyl ester
- Synonyms
- Propargyl-PEG1-Boc;Propargyl-PEG1-COOtBu;Alkyne-PEG1-CH2CH2COOtBu;PROPARGYL-PEG1-CH2CH2COOTBU;Propargyl-PEG1-t-butyl ester;tert-butyl 3-prop-2-ynoxypropanoate;tert-Butyl 3-(2-Propyn-1-yloxy)propanoate;3-(2-Propyn-1-yloxy)propanoic acid tert-butyl ester;Propanoic acid, 3-(2-propyn-1-yloxy)-, 1,1-dimethylethyl ester
- CBNumber
- CB43062616
- Molecular Formula
- C10H16O3
- Formula Weight
- 184.23
- MOL File
- 488150-84-1.mol
Propargyl-PEG1-t-butyl ester Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C10H16O3/c1-5-7-12-8-6-9(11)13-10(2,3)4/h1H,6-8H2,2-4H3
- InChIKey
- VDHVLESCKRSEAF-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)CCOCC#C
N-Bromosuccinimide Price
- Product number
- P839875
- Product name
- Propargyl-PEG1-t-butylester
- Packaging
- 50mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- P839875
- Product name
- Propargyl-PEG1-t-butylester
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-21980
- Product name
- Propargyl-PEG1-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BIPG1742
- Product name
- Propargyl-PEG1-t-butyl ester
- Packaging
- 250mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- AS107422
- Product name
- 3-(2-Propyn-1-yloxy)propanoicacidtert-butylester
- Purity
- 97%
- Packaging
- 250mg
- Price
- $215
- Updated
- 2021/12/16
Propargyl-PEG1-t-butyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG1-t-butyl ester has a propargyl group and a t-butyl protected carboxyl group. The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG1-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG1-t-butyl ester Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from Propargyl-PEG1-t-butyl ester manufacturers
- Product
- Propargyl-PEG1-COOtBu 488150-84-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26