Amino-PEG7-acid
- Product Name
- Amino-PEG7-acid
- CAS No.
- 2376111-92-9
- Chemical Name
- Amino-PEG7-acid
- Synonyms
- NH2-PEG7-PA;Amino-PEG7-acid;Amino-PEG7-propionic acid;Inhibitor,PROTAC Linkers,inhibit,Amino PEG7 acid,AminoPEG7acid,Amino-PEG-7-acid
- CBNumber
- CB43369445
- Molecular Formula
- C17H35NO9
- Formula Weight
- 397.47
- MOL File
- 2376111-92-9.mol
Amino-PEG7-acid Property
- Boiling point:
- 514.7±50.0 °C(Predicted)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- -20°C, sealed storage, away from moisture and light
- pka
- 4.28±0.10(Predicted)
- form
- Oil
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Amino-PEG7-acid Chemical Properties,Usage,Production
Uses
Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Amino-PEG7-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Amino-PEG7-acid Suppliers
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View Lastest Price from Amino-PEG7-acid manufacturers
- Product
- NH2-PEG7-PA 2376111-92-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-06
- Product
- NH2-PEG7-CH2CH2COOH 2376111-92-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2026-01-28
- Product
- Amino-PEG7-COOH 2376111-92-9
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-22