2-Amino-6-fluorobenzoic acid

Product Name: 2-Amino-6-fluorobenzoic acid
CAS No.: 434-76-4
Chemical Name: 2-Amino-6-fluorobenzoic acid
Synonyms: 6-FABA;BUTTPARK 44\01-59;TIMTEC-BB SBB006549;RARECHEM AL BO 0279;2-Amino-6-Fluorobenzoic;6-FLUOROANTHRANILIC ACID;2-amino-6-fluorobenzoate;6-FluoroanthranilicAcid>2-aMino-6-flourobenzoicacid;2-AMINO-6-FLUOROBENZOIC ACID
CBNumber: CB4351052
Molecular Formula: C7H6FNO2
Formula Weight: 155.13
MOL File: 434-76-4.mol

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2-Amino-6-fluorobenzoic acid Property

Melting point:: 167-169 °C (lit.)
Boiling point:: 223.67°C (rough estimate)
Density: 1.3021 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
pka: 4.01±0.10(Predicted)
form: Crystalline Powder
color: Yellow to brown
BRN: 3540926
InChIKey: RWSFZKWMVWPDGZ-UHFFFAOYSA-N
CAS DataBase Reference: 434-76-4(CAS DataBase Reference)
NIST Chemistry Reference: Anthralic acid, 6-fluoro-(434-76-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29224999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 443026
Product name: 2-Amino-6-fluorobenzoic acid
Purity: 98%
Packaging: 5g
Price: $30.8
Updated: 2023/01/07

TCI Chemical

Product number: F0475
Product name: 6-Fluoroanthranilic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $29
Updated: 2024/03/01

TCI Chemical

Product number: F0475
Product name: 6-Fluoroanthranilic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $87
Updated: 2024/03/01

Alfa Aesar

Product number: A10919
Product name: 2-Amino-6-fluorobenzoic acid, 98%
Packaging: 1g
Price: $34.65
Updated: 2024/03/01

Alfa Aesar

Product number: A10919
Product name: 2-Amino-6-fluorobenzoic acid, 98%
Packaging: 5g
Price: $114.65
Updated: 2024/03/01

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2-Amino-6-fluorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Used in the synthesis of a novel benzamide with potent neuroleptic activity. 5- fluoro-2-methyl-3,l-benzoxazin-4-one was obtained from 2-amino-6-fluorobenzoic acid. The condensation of 2-amino-6-fluorobenzoic acid methyl ester and (4-fluorophenyl) acetyl chloride with N,N-dimethylamino-4-pyridine in CH 2 Cl 2 to give 2-fluoro-6-[2-(4-fluoro-phenyl)-acetylamino]-benzoic acid methyl ester in 61% yield. 2 Amino 6 fluorobenzoic acid is another easily ac cessible synthon for construction of monofluorinated heterocycles. Reactions of 2,3,4,6-tetra-O-acetyl-n-D_glucopyranosyl bromide (2) with p-hydroxybenzaldehyde, trifluoromethyl and fluoro substi- tuted aniline and 2-amino-6-fluorobenzoic acid gave lO-(Pformyl- pheny1)-2,3,4,6-tetra-O-acetyl-(3-D-glucopyranoside. 2-Fluoro-6-iodobenzoic acid,a loose white crystal,was synthesized by using 2-amino-6-fluorobenzoic acid as the starting material.

Definition

ChEBI: 2-Amino-6-fluorobenzoic acid is an aminobenzoic acid.

reaction suitability

reaction type: solution phase peptide synthesis

storage

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Synthesis

The synthesis of 2-Amino-6-fluorobenzoic acid is as follows:
A 50 ml three-necked flask was charged with 1.85 g (10 mmol) of 6-fluoro-2-nitrobenzoic acid, 25.6 mg (0.2 mmol) of molybdenum dioxide, and 76.8 mg of activated carbon. 30 ml of absolute ethanol was added dropwise 1.25 g (20 mmol) of hydrazine hydrate (80%) at room temperature. After the reaction was completed at room temperature for 7 h, TLC monitoring showed that the reaction was completed, filtered, and the filtrate was concentrated, then ethyl acetate (20 mL) and water (10 ml) were added and extracted. The organic phase was washed with water and concentrated to give 1.5g desired product as a pale yellow solid, yield 96.8%, HPLC purity 99.6%.

2-Amino-6-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-6-fluorobenzoic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 2-Amino-6-fluorobenzoic acid 434-76-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-24

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Amino-6-fluorobenzoic acid 434-76-4
Price: US $0.10/KG
Min. Order: 0.1KG
Purity: 98%
Supply Ability: 200TONS
Release date: 2019-12-24

Honest Joy Holdings Limited

Product: 2-Amino-6-fluorobenzoic acid 434-76-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.4%
Supply Ability: 100 tons
Release date: 2022-02-20

434-76-4, 2-Amino-6-fluorobenzoic acidRelated Search:

Urethane 4-Aminobenzoic acid 4-Fluorobenzoic acid POLYURETHANE Glycine 6-Aminocaproic acid 2-AMINO-3,5-DIBROMO-6-FLUOROBENZOIC ACID 2,3,4,5-TETRAFLUORO-6-NITROBENZOIC ACID 2-AMINO-3,4,5,6-TETRAFLUOROBENZOIC ACID 2-Amino-4-Fluorobenzoic Acid 99%,2-AMINO-4-FLUOROBENZOIC ACID / 4-FLUOROANTHRANILIC ACID,2-AMINO-4-FLUOROBENZOIC ACID Anthranilic acid 2-AMINO-6-FLUORO-3-NITROBENZOIC ACID ETHYL ESTER 2-Fluoro-6-nitrobenzoic acid 3-AMINO-2,5,6-TRIFLUOROBENZOIC ACID 3-FLUORO-5-METHYLBENZYL ALCOHOL 4-Amino-2-Fluorobenzoic Acid 2-Fluoro-4-Aminobenzoic Acid 2-BROMO-5-FLUORO-4-METHYLBENZALDEHYDE 2-Amino-5-fluorobenzoic acid

BUTTPARK 44\01-59

6-FLUOROANTHRANILIC ACID

2-fluoro-6-aminobenzoic acid

TRIPHENYLBORANE, 0.25M SOLUTION IN TETRA

2-AMINO-6-FLUOROBENZOIC ACID (6-FLUOROANTHRANILIC ACID)

2-Amino-6-fluorobenzoic acid, 98% (6-Fluoroanthranilic acid)

2-Amino-6-Fluorobenzoic

2-Amino-6-fluorobenzoic acid 97%

RARECHEM AL BO 0279

TIMTEC-BB SBB006549

2-AMINO-6-FLUOROBENZOIC ACID

6-FABA (6-Fluoroanthranilic Acid)

2-Amino-6-fluorobenzoicacid97%

2-Amino-6-fluorobenzoic acid,98%

2-aMino-6-flourobenzoicacid

6-Fluoroanthranilic acid, 2-Carboxy-3-fluoroaniline

2-AMino-6-fluorobenzoic acid, 98% 1GR

2-AMino-6-fluorobenzoic acid SynonyMs 6-Fluoroanthranilic acid

Benzoicacid, 2-aMino-6-fluoro-

6-FABA

6-FluoroanthranilicAcid&gt

2-aMino-6-flourobenzoicacid,2-fluoro-6-aminobenzoic acid,6-FLUOROANTHRANILIC ACID,methyl 2-amino-6-fluoro-5-methylbenzoate,2-Amino-6-

2-amino-6-fluorobenzoate

434-76-4

1134-76-4

437-76-4

424-76-4

CARBOXYLIC ACID

Aromatic Amino Acids

Peptide Synthesis

Specialty Synthesis

Unnatural Amino Acid Derivatives

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Benzoic acid

Fluorin-contained Benzoic acid series