ChemicalBook > CAS DataBase List > 1-Methylpiperazin-2-one

1-Methylpiperazin-2-one

Product Name: 1-Methylpiperazin-2-one
CAS No.: 59702-07-7
Chemical Name: 1-Methylpiperazin-2-one
Synonyms: 1-Methylpiperazin-2-on;1-Methyl-2-piperazinone;-Methyl-piperazin-2-one;1-METHYL-PIPERAZIN-2-ONE;1-METHYL-PIPERAZINE-2-ONE;2-Piperazinone, 1-methyl-;1-Methylpiperazin-2-one ,97%;1-Methylpiperazin-2-one ,98%;1-methylpiperazin-2-one(SALTDATA: HCl)
CBNumber: CB4398851
Molecular Formula: C5H10N2O
Formula Weight: 114.15
MOL File: 59702-07-7.mol

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1-Methylpiperazin-2-one Property

Boiling point:: 242.1±33.0 °C(Predicted)
Density: 1.037±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Liquid
pka: 7.42±0.20(Predicted)
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C5H10N2O/c1-7-3-2-6-4-5(7)8/h6H,2-4H2,1H3
InChIKey: KJCIMSSFGUGTGA-UHFFFAOYSA-N
SMILES: N1(C)CCNCC1=O

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3684
Product name: 1-Methylpiperazin-2-one
Purity: min. 95.0 %
Packaging: 200MG
Price: $71
Updated: 2025/07/31

TCI Chemical

Product number: M3684
Product name: 1-Methylpiperazin-2-one
Purity: min. 95.0 %
Packaging: 1G
Price: $213
Updated: 2025/07/31

TRC

Product number: M331558
Product name: 1-Methylpiperazin-2-one
Packaging: 100mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: X7943
Product name: 1-Methylpiperazin-2-one
Packaging: 100mg
Price: $97
Updated: 2021/12/16

Matrix Scientific

Product number: 069257
Product name: 1-Methylpiperazin-2-one
Purity: 95+%
Packaging: 1g
Price: $127
Updated: 2021/12/16

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1-Methylpiperazin-2-one Chemical Properties,Usage,Production

Synthesis

110-85-0

59702-07-7

The general procedure for the synthesis of 1-methylpiperazin-2-one using piperazine as starting material was as follows: piperazine was dissolved in 70 mL of a 50% aqueous acetone solution containing 2.2 g of sodium hydroxide, and the resulting solution was stirred and reacted for 3 hours at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was added to acetone to precipitate insoluble impurities. The insoluble material was separated by filtration and the filtrate was removed from the acetone by distillation under reduced pressure. Finally, the residue was distilled under reduced pressure to give 5.2 g of 1-methylpiperazin-2-one with a boiling point of 104°C/4 mmHg in 91% yield.

References

[1] Patent: US4087424, 1978, A
[2] Patent: US4112090, 1978, A

1-Methylpiperazin-2-one Preparation Products And Raw materials

Raw materials

ZINC Sodium hydride Potassium tert-butoxide Hexane Ethylenediamine P-XYLENE Ethanol 2-Methylaminoethanol N,N-Dimethylformamide Sodium chloride Toluene Di-tert-butyl dicarbonate Benzylamine Sodium Triethylamine Palladium 1,4-Dioxane PETROLEUM ETHER 2-Chloro-N-MethylethanaMine Hydrochloride Tetrahydrofuran Ethanol anhydrous Ethyl acetate Hydrochloric acid N-Benzylglycine ethyl ester Sodium bicarbonate hydrogen Dichloromethane Benzyl chloroformate Acetic acid Methanol Sodium hydroxide Magnesium sulfate Thionyl chloride PETROLEUM ETHER Iodomethane Sulfuric acid Ethyl chloroacetate

Preparation Products

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View Lastest Price from 1-Methylpiperazin-2-one manufacturers

Career Henan Chemical Co

Product: 1-Methylpiperazin-2-one 59702-07-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1lg; 2kg; 5kg; 10kg; 100kg
Release date: 2019-08-31

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