ChemicalBook > CAS DataBase List > imidazo[1,2-a]pyridine-6-carboxylic acid

imidazo[1,2-a]pyridine-6-carboxylic acid

Product Name
imidazo[1,2-a]pyridine-6-carboxylic acid
CAS No.
139022-25-6
Chemical Name
imidazo[1,2-a]pyridine-6-carboxylic acid
Synonyms
EOS-60803;Olprinone Impurity 32;Imidazo[1,2-a]pyridine-6-...;6-Carboxyimidazo[1,2-a]pyridine;Imidazo[1,2-a]pyridine-6-carboxylicAci;6-imidazo[2,1-f]pyridinecarboxylic acid;iMidazo[1,2-a]pyridin-6-carboxylic acid;imidazo[2,1-f]pyridine-6-carboxylic acid;IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID;H-iMidazo[1,2-a]pyridin-6-carboxylic acid
CBNumber
CB4460305
Molecular Formula
C8H6N2O2
Formula Weight
162.15
MOL File
139022-25-6.mol
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imidazo[1,2-a]pyridine-6-carboxylic acid Property

Melting point:
250
Density 
1.41
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
0.67±0.41(Predicted)
form 
Solid
color 
Pale Beige to Light Beige
Stability:
Hygroscopic
InChI
InChI=1S/C8H6N2O2/c11-8(12)6-1-2-7-9-3-4-10(7)5-6/h1-5H,(H,11,12)
InChIKey
ONOJJCTXSDBVSP-UHFFFAOYSA-N
SMILES
C12=NC=CN1C=C(C(O)=O)C=C2
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-43
Safety Statements 
22-26-36/37/39-36/37
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
I387580
Product name
Imidazo[1,2-a]pyridine-6-carboxylicacid
Packaging
100mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H21-1-D5
Product name
Imidazo[1,2-a]pyridine-6-carboxylic acid
Purity
97.0%
Packaging
5G
Price
$64
Updated
2021/12/16
SynQuest Laboratories
Product number
4H21-1-D5
Product name
Imidazo[1,2-a]pyridine-6-carboxylic acid
Purity
97.0%
Packaging
1g
Price
$20
Updated
2021/12/16
Matrix Scientific
Product number
045476
Product name
Imidazo[1,2-a]pyridine-6-carboxylic acid
Purity
>95%
Packaging
1g
Price
$29
Updated
2021/12/16
AK Scientific
Product number
Y7487
Product name
H-Imidazo[1,2-a]pyridine-6-carboxylicacid
Packaging
250mg
Price
$71
Updated
2021/12/16
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imidazo[1,2-a]pyridine-6-carboxylic acid Chemical Properties,Usage,Production

Uses

Imidazo[1,2-a]pyridine-6-carboxylic acid is a brown solid that should be stored sealed at room temperature and away from light. It is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.

Synthesis

1314777-15-5

139022-25-6

Step 2. Imidazo[1,2-a]pyridine-6-carboxylic acid hydrochloride (170 g) was dissolved in water (600 mL) and heated until completely dissolved to form a clarified solution. Subsequently, the pH was adjusted to 5-6 by slowly adding 2 M NaOH aqueous solution. the reaction mixture was cooled to 0 °C in an ice-water bath. The precipitate precipitated was collected by vacuum filtration, washed with ethanol and dried under vacuum to afford the target product imidazo[1,2-a]pyridine-6-carboxylic acid (107.2 g, 77% yield) as a light yellow powder. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI+): 1H NMR δ 13.76-12.82 (br, 1H), 9.28 (s, 1H), 8.10 (s, 1H), 7.68 (s, 1H), 7.64-7.56 (m, 2H); MS (ESI+) m/z: 163 [M + H]+.

References

[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 130
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 81; 82
[3] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 59; 60
[4] Patent: WO2013/130943, 2013, A1. Location in patent: Paragraph 0181

imidazo[1,2-a]pyridine-6-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from imidazo[1,2-a]pyridine-6-carboxylic acid manufacturers

Honest Joy Holdings Limited
Product
Imidazo[1,2-a]pyridine-6-carboxylic acid 139022-25-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98.5%
Supply Ability
100 tons
Release date
2022-01-26
Dideu Industries Group Limited
Product
IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID 139022-25-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-25
Career Henan Chemical Co
Product
IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID 139022-25-6
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-08-05

139022-25-6, imidazo[1,2-a]pyridine-6-carboxylic acidRelated Search:

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