1-Methylpiperidin-4-amine
Uses- Product Name
- 1-Methylpiperidin-4-amine
- CAS No.
- 41838-46-4
- Chemical Name
- 1-Methylpiperidin-4-amine
- Synonyms
- N-Methyl-4-aminopiperidine;4-Amino-1-methyL;1-Methylpiperidin-4-;1-Methylpiperidin-4-amin;4-Amino-1-methylpiperdine;1-Methylpiperidin-4-amine;1-Methyl-4-piperidinaMine;1-Methylpiperidine-4-amine;1-Methyl-4-Amino Piperidine;(1-methyl-4-piperidyl)amine
- CBNumber
- CB4758082
- Molecular Formula
- C6H14N2
- Formula Weight
- 114.19
- MOL File
- 41838-46-4.mol
1-Methylpiperidin-4-amine Property
- Melting point:
- 203-207
- Boiling point:
- 62-64°C 1mm
- Density
- 0.91
- refractive index
- 1.4700-1.4740
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- clear liquid
- pka
- 9.92±0.20(Predicted)
- color
- Colorless to Light orange to Yellow
- InChI
- InChI=1S/C6H14N2/c1-8-4-2-6(7)3-5-8/h6H,2-5,7H2,1H3
- InChIKey
- ALOCUZOKRULSAA-UHFFFAOYSA-N
- SMILES
- N1(C)CCC(N)CC1
- CAS DataBase Reference
- 41838-46-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22-34-11
- Safety Statements
- 26-36/37/39-45-22-16-9
- RIDADR
- 2920
- HazardClass
- IRRITANT
- PackingGroup
- Ⅱ
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A2046
- Product name
- 4-Amino-1-methylpiperidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $55
- Updated
- 2025/07/31
- Product number
- A2046
- Product name
- 4-Amino-1-methylpiperidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $158
- Updated
- 2025/07/31
- Product number
- M320875
- Product name
- 1-Methylpiperidin-4-amine
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 072008
- Product name
- 4-Amino-1-methylpiperidine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $47
- Updated
- 2021/12/16
- Product number
- J92422
- Product name
- 4-Amino-1-methylpiperidine
- Packaging
- 25g
- Price
- $40
- Updated
- 2021/12/16
1-Methylpiperidin-4-amine Chemical Properties,Usage,Production
Uses
4-Amino-1-methylpiperidine is used as an organic reagent and pharmaceutical intermediate.
Chemical Properties
Clear colorless to yellow liquid
Synthesis
359878-09-4
41838-46-4
N-((4-methoxyphenyl)methyl)-4-amino-1-methylpiperidine (1 g, 4.27 mmol) was used as starting material, which was dissolved in a methanol solution of 4% formic acid (60 mL). Under argon protection, 10% Pd/C (1 g) was added to the reaction system and the reaction mixture was subsequently heated to reflux for 24 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was acidified with concentrated hydrochloric acid to a pH of about 1. The resulting solution was concentrated to give a yellow oily substance. The oily substance was purified by fast chromatography (eluent: methanol/dichloromethane = 3:7 with 3.5% ammonia) to give 249 mg (51% yield) of 4-amino-1-methylpiperidine (57-MBT36B) as a white solid. Thin layer chromatography (TLC) Rf value was 0.13 (unfolding agent: 10% dichloromethane solution in methanol with 3.5% ammonia). High performance liquid chromatography-mass spectrometry (HPLC-MS, Method B) showed the molecular ion peak MH+ = 115. ultraviolet/mass spectrometry (UV/MS) detection showed a percent purity of -/100.
References
[1] Patent: WO2007/124136, 2007, A1. Location in patent: Page/Page column 126-127
1-Methylpiperidin-4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
1-Methylpiperidin-4-amine Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from 1-Methylpiperidin-4-amine manufacturers
- Product
- 1-Methylpiperidin-4-amine 41838-46-4
- Price
- US $49.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2025-08-26
- Product
- 1-Methylpiperidin-4-amine 41838-46-4
- Price
- US $1.00/KG
- Min. Order
- 1000KG
- Purity
- 99.99%
- Supply Ability
- 10000t
- Release date
- 2021-09-01
- Product
- 1-Methylpiperidin-4-amine 41838-46-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-21