2-Iodoaniline
- Product Name
- 2-Iodoaniline
- CAS No.
- 615-43-0
- Chemical Name
- 2-Iodoaniline
- Synonyms
- O-IODOANILINE;2-lodoaniline;Aniline o-iodine;2-IodoaniL;2-Iodylamine;2-IODOANILINE;Aniline, 2-iodo-;Aniline, o-iodo-;2-Iodoaniline>2-iodo-benzenamin
- CBNumber
- CB5125267
- Molecular Formula
- C6H6IN
- Formula Weight
- 219.02
- MOL File
- 615-43-0.mol
2-Iodoaniline Property
- Melting point:
- 55-58 °C (lit.)
- Boiling point:
- 262.0±23.0 °C(Predicted)
- Density
- 1.8155 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Chloroform, DCM, Ethyl Acetate, Toluene
- pka
- 2.6(at 25℃)
- form
- Crystalline Needles
- color
- Yellow to brown
- Water Solubility
- Insoluble in water.
- Sensitive
- Light Sensitive
- BRN
- 2204899
- InChI
- 1S/C6H6IN/c7-5-3-1-2-4-6(5)8/h1-4H,8H2
- InChIKey
- UBPDKIDWEADHPP-UHFFFAOYSA-N
- SMILES
- Nc1ccccc1I
- CAS DataBase Reference
- 615-43-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenamine, 2-iodo-(615-43-0)
- EPA Substance Registry System
- o-Iodoaniline (615-43-0)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-37/38-36/37/38
- Safety Statements
- 36/37-36/37/39-26-36
- RIDADR
- 2811
- WGK Germany
- 3
- F
- 8
- Hazard Note
- Irritant
- TSCA
- TSCA listed
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29214210
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I7004
- Product name
- 2-Iodoaniline
- Purity
- 98%
- Packaging
- 5g
- Price
- $51.7
- Updated
- 2025/07/31
- Product number
- I7004
- Product name
- 2-Iodoaniline
- Purity
- 98%
- Packaging
- 25g
- Price
- $127
- Updated
- 2025/07/31
- Product number
- I0046
- Product name
- 2-Iodoaniline
- Packaging
- 5G
- Price
- $36
- Updated
- 2025/07/31
- Product number
- I0046
- Product name
- 2-Iodoaniline
- Packaging
- 25G
- Price
- $101
- Updated
- 2025/07/31
- Product number
- I693835
- Product name
- 2-Iodoaniline
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
2-Iodoaniline Chemical Properties,Usage,Production
Chemical Properties
YELLOW TO BROWN CRYSTALLINE NEEDLES
Uses
2-Iodoaniline is used as an intermediate in organic synthesis.
Uses
2-Iodobenzenamine is an synthetic intermediate for the synthesis of complex organic compounds and pharmaceuticals.
Preparation
2-iodoaniline and its derivatives are commonly used for the preparation of indole-based anticancer drugs, which have high market value, and further synthesis can lead to high-end synthetic intermediates with complex structures.
Take a reaction tube, add 50mg of sodium azide, 75mg of 1-(2-iodophenyl)ethanol, 300uL of trifluoroacetic acid, 150uL of methanesulfonic acid and 1.0mL of hexane, and stir for 24 hours at 40℃. After the reaction, 10 mL of sodium hydroxide solution was added to quench the reaction. The organic phase was washed with 5 mL of brine, and the organic phase was combined and separated by column chromatography to obtain 58.4 mg of 2-iodoaniline in 89% yield.
Synthesis of 2-iodoaniline
Purification Methods
Distil 2-iodoaniline with steam and crystallise it from *benzene/pet ether. The N-acetyl derivative has m 110o. [Beilstein 12 IV 1542.]
2-Iodoaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Iodoaniline manufacturers
- Product
- 2-iodoaniline 615-43-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-08-19
- Product
- 2-Iodoaniline 615-43-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- 2-Iodoaniline 615-43-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2025-03-14