HUMAN M-CSF

Description Source Background

Product Name: HUMAN M-CSF
CAS No.: 81627-83-0
Chemical Name: HUMAN M-CSF
Synonyms: Csfm;csf-1;M-CSF;MGI-IM;mCSF-1;mM-CSF;RHM-CSF;MGC31930;M-CSF rat;Lanimostim
CBNumber: CB5201242
Formula Weight: 0
MOL File: Mol file

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HUMAN M-CSF Property

storage temp.: -20°C
form: lyophilized powder
color: white to off-white
biological source: rat

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-26
WGK Germany: 3
RTECS: GI5500000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: WH0001435M1
Product name: Monoclonal Anti-CSF1 antibody produced in mouse
Purity: clone 1A9, purified immunoglobulin, buffered aqueous solution
Packaging: 100μg
Price: $406
Updated: 2025/07/31

Sigma-Aldrich

Product number: SRP3332
Product name: M-CSF rat
Purity: Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Packaging: 10μg
Price: $432
Updated: 2025/07/31

Sigma-Aldrich

Product number: SRP3221
Product name: M-CSF from mouse
Purity: Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Packaging: 10μG
Price: $259
Updated: 2025/07/31

Sigma-Aldrich

Product number: SRP3110
Product name: M-CSF human
Purity: Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Packaging: 10μg
Price: $259
Updated: 2025/07/31

Sigma-Aldrich

Product number: M9170
Product name: Macrophage Colony-Stimulating Factor from mouse
Purity: M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Packaging: 10μg
Price: $225
Updated: 2025/07/31

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HUMAN M-CSF Chemical Properties,Usage,Production

Uses

Antineoplastic; anti-infective growth factor that acts on both progenitor and mature cells of the macrophage line.

Uses

Macrophage Colony-Stimulating Factor from mouse has been used:

in the initiation of osteoclastogenesis in bone marrow monocyte cells
to stimulate osteoclast differentiation in non-adherent hematopoietic cell
for the generation of blood-derived stem cells

General Description

M-CSF (macrophage colony-stimulating factor) is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. The protein works through its receptor CSF1R (colony stimulating factor 1 receptor). The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant murine M-CSF is a 36.4kDa homodimeric protein containing two 156 amino acid polypeptide subunits.

Biochem/physiol Actions

M-CSF (macrophage colony-stimulating factor) is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. M-CSF also works as a pleiotropic growth factor and plays a crucial role in reproduction and organogenesis. Absence of it can result in reduced growth, neurological and reproductive problems, developmental defects in the mammary gland, bone and pancreas. M-CSF is also involved in the pathogenesis of cancer.

Description

Macrophage Colony Stimulating Factor Human Recombinant produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids and having a total molecular mass of 37.1 KD. MCSF is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. MCSF induces cells of the monocyte/macrophage lineage. MCSF plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.

HUMAN M-CSF Preparation Products And Raw materials

Raw materials

Preparation Products

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HUMAN M-CSF Suppliers

China 174 Germany 2 Japan 2 Switzerland 1 United Kingdom 1 United States 15 Global 195

Creative Peptides

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Country: United States
ProdList: 6083
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United States Biological

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HONEST JOY HOLDINGS LIMITED

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Country: United States
ProdList: 6675
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Accurate Chemical & Scientific Corporation.

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Advantage: 72

Abcam Limited

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ProdList: 6001
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Riedel-de Haen AG

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ProdList: 6773
Advantage: 87

EMD Biosciences, Inc.

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Country: United States
ProdList: 6529
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MP Biomedicals, Inc.

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ProdList: 6561
Advantage: 81

PeproTech Inc.

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ProdList: 644
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BIODESIGN International/OEM Concepts

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Country: United States
ProdList: 2376
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R & D Systems

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Country: United States
ProdList: 2195
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BioSource International, Inc.

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ProdList: 1011
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Chemicon Internatinal, Inc.

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AUSTRAL Biologicals

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Cell Sciences, Inc.

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81627-83-0, HUMAN M-CSFRelated Search:

2,4-PENTANEDIONE, SILVER DERIVATIVE Cupric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE Tris(2,4-pentanedionato)chroMiuM(III) METHYL ISOCYANOACETATE Aluminum acetylacetonate TERT-BUTYL ISOCYANIDE Ethyl isocyanoacetate Tosylmethyl isocyanide DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) N-BUTYLISOCYANIDE Benzyl isocyanide PHENYLSELENOL SALCOMINE Ferric acetylacetonate HUMAN G-CSF,HUMAN GM-CSF-BETA

colony-stimulatingfactor1

csf-1

MGI-IM

Monoclonal Anti-CSF1 antibody produced in mouse

MGC31930

ANTI-M-CSF (CENTER) antibody produced in rabbit

Lanimostim

Macrophage colony-stimulating factor 1

Processed macrophage colony-stimulating factor 1

Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli

MACROPHAGE COLONY STIMULATOR FACTOR (M-CSF) HUMAN

MACROPHAGE COLONY STIMULATING FACTOR

MACROPHAGE COLONY STIMULATING FACTOR, HUMAN

MACROPHAGE COLONY-STIMULATING FACTOR, HUMAN, RECOMBINANT

M-CSF

M-CSF, HUMAN

HUMAN M-CSF

HUMAN MACROPHAGE COLONY STIMULATING FACTOR

HUMAN MGI-IM

HUMAN CSF-1

Macrophage Colony-StimulatingFactor, Human, Recomb.

MACROPHAGE-COLONY STIMULATING FACTOR, HU MAN RECOMBINANT EXPRESSED IN E. COLI

macrophagehumanrecombinantexpressedinyeast95+%

macrophage colony-stimulating factor from mouse

FOR USE IN THE MANUFACTURE OF MEDICAMENTS OF HS NO. 3002

mCSF-1

mM-CSF

M-CSF from rat

M-CSF rat

M-CSF from mouse

cytokines,macrophagecolony-stimulatingfactor

monocytecolony-stimulatingfactor

RHM-CSF

RECOMBINANT HUMAN M-CSF

NATURAL HUMAN CSF-1

NATURAL HUMAN MACROPHAGE-COLONY STIMULATING FACTOR

NATURAL HUMAN M-CSF

Recombinant Mouse M-Csf/Csf1 Protein, No Tag

Recombinant Human M-CSF/CSF1 Protein, His Tag

Recombinant Rat M-Csf/Csf1 Protein, No Tag

Recombinant Human M-CSF, HUMAN M-CSF

Macrophage Colony-Stimulating Factor, Human, Recombinant, <i>E. coli</i>

Csfm

Recombinant Human M-CSF, 33-255aa, His-tag

81627-83-0

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Cytokines and Growth Factors

Cytokines, Growth Factors and Hormones

Hematopoietic Cytokines