2-Fluoro-3-iodopyridine
- Product Name
- 2-Fluoro-3-iodopyridine
- CAS No.
- 113975-22-7
- Chemical Name
- 2-Fluoro-3-iodopyridine
- Synonyms
- uoro-3-iodopyridine;2-FLUORO-3-IODOPYRIDINE;2-Fluoro-3-iodopyridine>PYRIDINE, 2-FLUORO-3-IODO-;2-Fluoro-3-Iodopyridine 98%;2-Fluoro-3-iodopyridine ,98%;2-Fluoro-3-iodopyridine, 97+%;2-Fluoro-3-iodopyridine ISO 9001：2015 REACH
- CBNumber
- CB5228823
- Molecular Formula
- C5H3FIN
- Formula Weight
- 222.99
- MOL File
- 113975-22-7.mol
2-Fluoro-3-iodopyridine Property
- Melting point:
- 45 °C
- Boiling point:
- 99°C/17mmHg(lit.)
- Density
- 2.046±0.06 g/cm3(Predicted)
- Flash point:
- >110°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- -2.45±0.10(Predicted)
- form
- powder to crystal
- color
- White to Light yellow
- Sensitive
- Light Sensitive
- InChIKey
- WCDCAXVNBOLWNO-UHFFFAOYSA-N
- CAS DataBase Reference
- 113975-22-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38-41-37/38
- Safety Statements
- 22-26-36/37/39-39-37
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 755389
- Product name
- 2-Fluoro-3-iodopyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $68
- Updated
- 2023/06/20
- Product number
- F0733
- Product name
- 2-Fluoro-3-iodopyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $38
- Updated
- 2025/07/31
- Product number
- F0733
- Product name
- 2-Fluoro-3-iodopyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $126
- Updated
- 2025/07/31
- Product number
- F598830
- Product name
- 2-Fluoro-3-iodopyridine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- F598830
- Product name
- 2-Fluoro-3-iodopyridine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
2-Fluoro-3-iodopyridine Chemical Properties,Usage,Production
Chemical Properties
Salmon-coloured solid
Uses
2-Fluoro-3-iodopyridine is typically used in scientific research and should not be used as a medicine, home remedy, or for other purposes.
Synthesis
372-48-5
113975-22-7
General procedure for the synthesis of 2-fluoro-3-iodopyridine from 2-fluoropyridine: LDA (25.8 mL of a 2M THF solution, 51.5 mmol) was added slowly and dropwise to an anhydrous THF (50 mL) solution of 2-fluoropyridine (5.0 g, 51.5 mmol) at -78 °C. The reaction mixture was stirred continuously at -78 °C for 1 hour. Subsequently, a THF (30 mL) solution of I2 (13.07 g, 51.5 mmol) was added dropwise to the reaction system at the same temperature. After the reaction mixture continued to be stirred at -78 °C for 3 h, the reaction was quenched by the addition of H2O (10 mL) and slowly warmed to room temperature. Na2SO3 (50 mL, 2 M solution in water) was added to remove excess iodine. The organic layer was separated, washed with brine, dried over anhydrous Na2SO4 and then concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford 2-fluoro-3-iodopyridine (9.6 g, 83.6% yield) as a white solid. lC/MS analysis: m/z (M++H) = 224.
References
[1] Patent: EP1559320, 2005, A1. Location in patent: Page/Page column 6
[2] Journal of Organic Chemistry, 2002, vol. 67, # 10, p. 3487 - 3493
[3] Tetrahedron Letters, 2004, vol. 45, # 36, p. 6697 - 6701
[4] Patent: WO2013/6792, 2013, A1. Location in patent: Paragraph 0188
[5] Tetrahedron, 2004, vol. 60, # 29, p. 6113 - 6120
2-Fluoro-3-iodopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluoro-3-iodopyridine Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 2-Fluoro-3-iodopyridine manufacturers
- Product
- 2-Fluoro-3-iodopyridine 113975-22-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-04
- Product
- 2-Fluoro-3-iodopyridine 113975-22-7
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 2-Fluoro-3-iodopyridine 113975-22-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-01