ChemicalBook > CAS DataBase List > 3-Amino-2-chloro-4-methylpyridine

3-Amino-2-chloro-4-methylpyridine

Product Name
3-Amino-2-chloro-4-methylpyridine
CAS No.
133627-45-9
Chemical Name
3-Amino-2-chloro-4-methylpyridine
Synonyms
2-CHLORO-4-METHYLPYRIDIN-3-AMINE;2-CHLORO-3-AMINO-4-METHYLPYRIDINE;Capic;TIMTEC-BB SBB010194;3-Amino-2-chloro-4-p;ASINEX-REAG BAS 13794917;2-CHLORO-3-AMINO-4-PICOLINE;3-AMINO-2-CHLORO-4-PICOLINE;2-Chloro-3-Amino-4-Methylpyrid;2-Chlor-4-Methylpyridin-3-Amin
CBNumber
CB5240863
Molecular Formula
C6H7ClN2
Formula Weight
142.59
MOL File
133627-45-9.mol
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3-Amino-2-chloro-4-methylpyridine Property

Melting point:
65-70 °C
Boiling point:
283.3±35.0 °C(Predicted)
Density 
1.260±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform, Ethanol
pka
3.22±0.10(Predicted)
form 
Crystals
color 
Off White
InChI
InChI=1S/C6H7ClN2/c1-4-2-3-9-6(7)5(4)8/h2-3H,8H2,1H3
InChIKey
UOBCYTOUXLAABU-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=CC(C)=C1N
CAS DataBase Reference
133627-45-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36/37/39-36-39
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
708135
Product name
3-Amino-2-chloro-4-methylpyridine
Purity
97%
Packaging
5g
Price
$66.1
Updated
2023/06/20
Sigma-Aldrich
Product number
708135
Product name
3-Amino-2-chloro-4-methylpyridine
Purity
97%
Packaging
1g
Price
$24
Updated
2023/01/07
TCI Chemical
Product number
A1855
Product name
3-Amino-2-chloro-4-methylpyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$43
Updated
2024/03/01
TCI Chemical
Product number
A1855
Product name
3-Amino-2-chloro-4-methylpyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$129
Updated
2024/03/01
Alfa Aesar
Product number
H26058
Product name
3-Amino-2-chloro-4-methylpyridine, 97%
Packaging
5g
Price
$125
Updated
2021/12/16
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3-Amino-2-chloro-4-methylpyridine Chemical Properties,Usage,Production

Chemical Properties

Off White Crystals

Uses

3-Amino-2-chloro-4-methylpyridine, also known as CAPIC, is a key intermediate in the production of nevirapine, a non-nucleosidic reverse transcriptase inhibitor that has been established to be clinically useful for the treatment of infection by HIV-1.

Preparation

3-Amino-2-chloro-4-methylpyridine can be obtained by reacting 2-chloro-4-methylnicotinamide with strong bases and halides.

3-Amino-2-chloro-4-methylpyridine Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Hydrochloric acid 3-Amino-4-methylpyridine

Preparation Products

Nevirapine
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3-Amino-2-chloro-4-methylpyridine Suppliers

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View Lastest Price from 3-Amino-2-chloro-4-methylpyridine manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
3-Amino-2-chloro-4-methylpyridine 133627-45-9
Price
US $80.00-800.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-31
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
2-Chlor-4-methylpyridin-3-amin 133627-45-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99.6%
Supply Ability
100000
Release date
2024-04-23
Hebei Duling International Trade Co. LTD
Product
3-Amino-2-chloro-4-methylpyridine 133627-45-9
Price
US $62.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 tons
Release date
2023-04-25

133627-45-9, 3-Amino-2-chloro-4-methylpyridineRelated Search:

6-Aminocaproic acid Pyridine DIMETHYLAMINOPYRIDINE, POLYMER-BOUND 4-Dimethylaminopyridine 2-Aminopyridine 2-Chloro-3-pyridinamine 3-Amino-4-methylpyridine 2-Chloro-5-chloromethylpyridine METSULFURON METHYL 4-Methylpyridin-2-amine 4-Aminopyridine 3-Aminopyridine Glycine Tribenuron methyl Thiophanate-methyl Methyl acetate 2-Chloro-3-picoline 2-Chloro-4-methyl-3-nitropyridine

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  • 133627-45-9
  • 133627-45
  • 33627-45-9
  • C6H7C1N2
  • C7H4ClF3O4
  • Halopyridines
  • Chloropyridines
  • Building Blocks
  • C5 to C6
  • C6
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • API Intermediate
  • (intermediate of nevirapine)
  • Aromatics Compounds
  • Chloropyridines
  • Halopyridines
  • Aromatics
  • Bases & Related Reagents
  • Nucleotides
  • Pyridines, Pyrimidines, Purines and Pteredines
  • pharmacetical
  • Amines
  • Pyridines