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4-Methoxystyrene

Product Name
4-Methoxystyrene
CAS No.
637-69-4
Chemical Name
4-Methoxystyrene
Synonyms
4-VINYLANISOLE;P-METHOXYSTYRENE;vinylanisole;4-Vinylanisol;p-Vinylanisole;4-METHOXYSTYRENE;p-Anisylethylene;Anisole, p-vinyl-;PARA-METHOXYSTYRENE;4-Methoxystyrene,98%
CBNumber
CB5246416
Molecular Formula
C9H10O
Formula Weight
134.18
MOL File
637-69-4.mol
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4-Methoxystyrene Property

Melting point:
2°C
Boiling point:
41-42 °C/0.5 mmHg (lit.)
Density 
1.009 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.562
Flash point:
170 °F
storage temp. 
Store at <= 20°C.
solubility 
Slightly miscible with methanol.
form 
Liquid
Specific Gravity
1.009
color 
Clear colorless to yellow
Odor
sweet
BRN 
1098935
LogP
2.874 (est)
CAS DataBase Reference
637-69-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1-ethenyl-4-methoxy-(637-69-4)
EPA Substance Registry System
Benzene, 1-ethenyl-4-methoxy- (637-69-4)
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Safety

Safety Statements 
23-24/25
WGK Germany 
3
HS Code 
29093090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
141003
Product name
4-Vinylanisole
Purity
97%
Packaging
5g
Price
$143
Updated
2024/03/01
Sigma-Aldrich
Product number
141003
Product name
4-Vinylanisole
Purity
97%
Packaging
25g
Price
$239.4
Updated
2024/03/01
TCI Chemical
Product number
M0130
Product name
4-Methoxystyrene (stabilized with TBC)
Purity
>98.0%(GC)
Packaging
10mL
Price
$99
Updated
2024/03/01
TCI Chemical
Product number
M0130
Product name
4-Methoxystyrene (stabilized with TBC)
Purity
>98.0%(GC)
Packaging
25mL
Price
$198
Updated
2024/03/01
Alfa Aesar
Product number
B22353
Product name
4-Methoxystyrene, 98%, stab. with 0.1% 4-tert-butylcatechol
Packaging
5g
Price
$69.6
Updated
2024/03/01
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4-Methoxystyrene Chemical Properties,Usage,Production

Description

4-Methoxystyrene (Para-methoxystyrene) is an important chemical raw material, can replace styrene compounds, and is widely applied to various fields such as a light polymerization inhibitor, a material, a medical intermediate, a pesticide, an adhesive, a coating, a sun-screening agent and the like. Besides, the p-methoxystyrene can be used as a polymerization monomer to synthesize polymers with different structures, and the synthesized polymer contains a protecting group which is easily subjected to acidolysis by light so that the p-methoxystyrene can be used as an excellent corrosion-resistant material to be applied to the electronic information industry.

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

4-Methoxystyrene is employed in the ferric chloride-catalyzed addition of activated methylenes to styrenes. It acts as a monomer in polymerization reactions. Further, it is used to prepare 1,1,2,2-Tetracyano-3-(p-methoxyphenyl)cyclobutane by reacting with ethenetetracarbonitrile.

Synthesis Reference(s)

Chemistry Letters, 13, p. 1897, 1984
The Journal of Organic Chemistry, 52, p. 422, 1987 DOI: 10.1021/jo00379a020
Tetrahedron Letters, 35, p. 8773, 1994 DOI: 10.1016/S0040-4039(00)78494-2

Synthesis

The current methods for synthesizing 4-Methoxystyrene mainly comprise:
P-methoxy styrene is prepared by taking p-methoxy benzyl alcohol as a raw material and reacting with triphenylphosphine, formaldehyde and hydrobromic acid through the Wittig reaction.
P-methoxyacetophenone is used as a raw material, reduced to 1- (4-methoxyphenyl) ethanol by potassium borohydride, esterified with excessive potassium bisulfate in cyclohexane to generate sulfonic acid-1- (4-methoxyphenyl) ethyl ester, and finally subjected to elimination reaction to obtain 4-Methoxystyrene.
In 2021, an invention discloses a method for synthesizing 4-methoxystyrene, which comprises the steps of using p-methoxyacetophenone as a raw material, firstly carrying out hydrogenation reduction to generate 1- (4-methoxyphenyl) ethanol, then carrying out dehydration elimination reaction to obtain a crude product, and finally rectifying to obtain the 4-methoxystyrene. The invention adopts a catalytic hydrogenation method to get the intermediate 1- (4-methoxyphenyl) ethanol. The reaction selectivity of the step is excellent and can reach 98-99%, and meanwhile, hydrogen is used as a cleaning gas so that environmental pollution is avoided and industrial production is facilitated.

4-Methoxystyrene Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxystyrene Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
FUJIFILM Wako Pure Chemical Corporation
Tel
--
Fax
--
Email
ffwk-cservice@fujifilm.com
Country
Japan
ProdList
6222
Advantage
58
HOKKO Chemical Industry Co.,Ltd.
Tel
--
Fax
--
Email
toiawase@hokkochem.co.jp
Country
Japan
ProdList
163
Advantage
73
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from 4-Methoxystyrene manufacturers

Shanghai Qyubiotech Co., Ltd.
Product
4-Methoxystyrene 637-69-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%+
Supply Ability
1000000kg per Month
Release date
2023-04-10
Chongqing Chemdad Co., Ltd
Product
4-Methoxystyrene 637-69-4
Price
US $200.00/KG
Min. Order
1KG
Purity
0.98
Supply Ability
20 tons
Release date
2024-06-03
Henan Fengda Chemical Co., Ltd
Product
4-Methoxystyrene 637-69-4
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-25

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