ChemicalBook > CAS DataBase List > 1,3-Dichloro-4-fluorobenzene

1,3-Dichloro-4-fluorobenzene

Product Name: 1,3-Dichloro-4-fluorobenzene
CAS No.: 1435-48-9
Chemical Name: 1,3-Dichloro-4-fluorobenzene
Synonyms: 2,4-DICHLORO-1-FLUOROBENZENE;2,4-DICHLOROFLUOROBENZENE;2,4-Dichlorofluorobenzene 99%;2,4-Dichloro-1-fluor;2,4-Dichlorofluobenzene;1,3-DICHLOROFLUOROBENZENE;2,4- twochlorofluorobenzene;2,4-Dichlorofluorobenzene99%;1,3-DICHLORO-4-FLUOROBENZENE;2,4-Dichlorofluorobenzene>
CBNumber: CB5257704
Molecular Formula: C6H3Cl2F
Formula Weight: 164.99
MOL File: 1435-48-9.mol

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1,3-Dichloro-4-fluorobenzene Property

Melting point:: -23 °C
Boiling point:: 172-174 °C(lit.)
Density: 1.409 g/mL at 25 °C(lit.)
refractive index: n20/D 1.525(lit.)
Flash point:: 98 °F
storage temp.: Sealed in dry,Room Temperature
form: clear liquid
color: Colorless to Light yellow to Light orange
Specific Gravity: 1.409
Water Solubility: insoluble
BRN: 2500791
InChI: InChI=1S/C6H3Cl2F/c7-4-1-2-6(9)5(8)3-4/h1-3H
InChIKey: BDJZCCWUSOZUQG-UHFFFAOYSA-N
SMILES: C1(F)=CC=C(Cl)C=C1Cl
CAS DataBase Reference: 1435-48-9(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Dichloro-4-fluorobenzene(1435-48-9)

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Safety

Hazard Codes: Xn,N,Xi
Risk Statements: 22-38-48/20/22-51/53-10-36/37/38
Safety Statements: 36/37-61-16-36-26
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 9
PackingGroup: III
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H227Combustible liquid

H302Harmful if swallowed

H315Causes skin irritation

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: D2059
Product name: 2,4-Dichlorofluorobenzene
Purity: >96.0%(GC)
Packaging: 25g
Price: $29
Updated: 2025/07/31

TCI Chemical

Product number: D2059
Product name: 2,4-Dichlorofluorobenzene
Purity: >96.0%(GC)
Packaging: 500g
Price: $214
Updated: 2025/07/31

TRC

Product number: D438810
Product name: 2,4-Dichlorofluorobenzene
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 1600-7-04
Product name: 2,4-Dichlorofluorobenzene
Purity: 98%
Packaging: 100g
Price: $96
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD104751
Product name: 1,3-dichloro-4-fluorobenzene
Packaging: 500g
Price: $600
Updated: 2021/12/16

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1,3-Dichloro-4-fluorobenzene Chemical Properties,Usage,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

1, 3-dichloro-4-fluorobenzene is a multifunctional chemical reagent. Its benzene ring structure formula contains fluorine and chlorine functional groups and can be used in various reaction systems. It is widely applied in the field of organic synthesis.

Synthesis

350-30-1

1435-48-9

The general procedure for the synthesis of 2,4-dichlorofluorobenzene from 3-chloro-4-fluoronitrobenzene is as follows: 240 g (1.37 mol) of 3-chloro-4-fluoronitrobenzene was added to a 250 ml four-necked flask and the temperature of the reaction system was raised to 170°C. The temperature of the reaction system was raised to 170°C. The reaction system was then purged with dry chlorine. Dry chlorine gas was slowly passed in the temperature range of 170 to 180 °C. The reaction process was carried out by distillation for 8 hours and the distillate was collected. The distillate was subsequently washed with water and then with alkali to a weakly basic pH. The organic phase was separated and purified by distillation, resulting in 207 g of 2,4-dichlorofluorobenzene with 99.8% purity and 91.7% yield.

References

[1] Patent: CN102249881, 2016, B. Location in patent: Paragraph 0020; 0075-0076
[2] Recueil des Travaux Chimiques des Pays-Bas, 1932, vol. 51, p. 98,109

1,3-Dichloro-4-fluorobenzene Preparation Products And Raw materials

Raw materials

4-Nitrobenzoyl chloride 3-Chloro-4-fluoroaniline Fluorobenzene 5-Chloro-2-fluoronitrobenzene 2,4-Dinitrofluorobenzene 3-Chloro-4-fluoronitrobenzene

Preparation Products

3-BROMO-2,4-DICHLORO-5-FLUORONITROBENZENE 2,4-Dichloro-5-fluoronitrobenzene Ciprofloxacin hydrochloride 1-(2,4-DICHLORO-5-FLUORO-3-METHOXYPHENYL)ETHANONE 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxoquinoline-3-carboxylic acid 2,4-DICHLORO-5-FLUORO-3-METHOXYNITRO-BENZENE 2,4-DICHLORO-5-FLUORO-3-METHOXYBENZOIC ACID 2,4-Dichloro-5-fluoroacetophenone 2,4-Dichloro-5-fluoro-3-methoxybenzoyl chloride 1-AMINO-2,4-DICHLORO-5-FLUORO-3-METHOXYBENZENE Ciprofloxacin 2,4-Dichloro-5-fluorobenzoic acid 3-BROMO-2,6-DICHLORO-5-FLUORO-1-METHOXYBENZENE

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View Lastest Price from 1,3-Dichloro-4-fluorobenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,3-Dichloro-4-fluorobenzene 1435-48-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-10

Henan Fengda Chemical Co., Ltd

Product: 1,3-Dichloro-4-fluorobenzene 1435-48-9
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Anhui Zhongda Biotechnology Co., Ltd

Product: 1,3-Dichloro-4-fluorobenzene 1435-48-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100T
Release date: 2023-10-31

1435-48-9, 1,3-Dichloro-4-fluorobenzeneRelated Search:

Florfenicol 1,3-Difluorobenzene 4-Fluorobenzonitrile Fluorobenzene Transfluthrin 4,6-Dichloropyrimidine 1,2-Dichloroethane 4-Fluorobenzaldehyde Dichloroacetic acid 2,6-dichloro-1-fluorobenzene,1,3-Dichloro-2-fluorobenzene, 98+%,1,3-DICHLORO-2-FLUOROBENZENE Teflubenzuron 2,4-Dichloro-5-fluoroacetophenone 2,4-DICHLORO-5-FLUOROBENZALDEHYDE, 97 2,4-Dichloro-5-fluoronitrobenzene 1,3,5-Trichloro-2,4,6-trifluorobenzene 1,3-DICHLORO-2,4,6-TRIFLUOROBENZENE 1,3-DICHLORO-2,4-DIFLUOROBENZENE METHYL 2,4-DICHLORO-5-FLUOROBENZOATE

2,4-Dichlorofluorobenzene 99%

2,4-Dichlorofluorobenzene99%

DCFB 2,4-Dichlorofluorobenzen

1,3-Dichloro-4-fluorobenzene,99%

2,4-DICHLOROFLUOROBENZENECIPROFLOXACIN

N-[4-(trichloromethylthio)sulfonylphenyl]acetamide

2,4-Dichloro-1-fluor

2,4-Dichlorofluobenzene

2,4- twochlorofluorobenzene

Benzene,2,4-dichloro-1-fluoro-

2,4-DICHLORO-1-FLUOROBENZENE

2,4-DICHLOROFLUOROBENZENE

2,4-DichloroFluorobenzene99.5%

1,3-DICHLORO-4-FLUOROBENZENE

1,3-DICHLOROFLUOROBENZENE

2,4-Dichlorofluorobenzene&gt

1,3-Dichloro-4-fluorobenzene ISO 9001：2015 REACH

1435-48-9

1435-38-9

Aryl

Building Blocks

Organic Building Blocks

Halogenated Hydrocarbons

Aromatic Hydrocarbons (substituted) & Derivatives

Fluorobenzene

Chlorine Compounds

Fluorine Compounds

Aryl

Halogenated Hydrocarbons

bc0001

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