ChemicalBook > CAS DataBase List > 4-Amino-5-imidazolecarboxamide hydrochloride

4-Amino-5-imidazolecarboxamide hydrochloride

Product Name
4-Amino-5-imidazolecarboxamide hydrochloride
CAS No.
72-40-2
Chemical Name
4-Amino-5-imidazolecarboxamide hydrochloride
Synonyms
AICA;AICA HCL;AIC .cntdot. HCl;AICA HYDROCHLORIDE;TIMTEC-BB SBB003938;5-Amino-1H-imidazoL;LABOTEST-BB LT00440910;e-4-carboxamide hydrochL;Temozolomide intermediate;Dacarbazine EP Impurity B
CBNumber
CB5300628
Molecular Formula
C4H7ClN4O
Formula Weight
162.58
MOL File
72-40-2.mol
More
Less

4-Amino-5-imidazolecarboxamide hydrochloride Property

Melting point:
250-252 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
water: soluble50mg/mL, clear, light yellow
form 
Crystals or Crystalline Powder
color 
White
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
BRN 
3701645
Stability:
Hygroscopic
InChI
InChI=1S/C4H6N4O.ClH/c5-3-2(4(6)9)7-1-8-3;/h1H,5H2,(H2,6,9)(H,7,8);1H
InChIKey
MXCUYSMIELHIQL-UHFFFAOYSA-N
SMILES
C1(N=CNC=1N)C(=O)N.Cl
CAS DataBase Reference
72-40-2(CAS DataBase Reference)
NIST Chemistry Reference
Imidazole-4(5)-carboxamide, 5-(4)-amino-, hydrochloride(72-40-2)
EPA Substance Registry System
1H-Imidazole-4-carboxamide, 5-amino-, monohydrochloride (72-40-2)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
RTECS 
NI3911000
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29332990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
164968
Product name
5-Amino-4-imidazolecarboxamide hydrochloride
Purity
98%
Packaging
5g
Price
$23.6
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2304
Product name
Dacarbazine Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$534
Updated
2024/03/01
Sigma-Aldrich
Product number
1162320
Product name
Dacarbazine Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
A1175
Product name
5(4)-Amino-4(5)-(aminocarbonyl)imidazole Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$55
Updated
2024/03/01
TCI Chemical
Product number
A1175
Product name
5(4)-Amino-4(5)-(aminocarbonyl)imidazole Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$203
Updated
2024/03/01
More
Less

4-Amino-5-imidazolecarboxamide hydrochloride Chemical Properties,Usage,Production

Chemical Properties

very slightly beige fine powder

Uses

5-Amino-4-imidazolecarboxamide hydrochloride was used in the synthesis of heterocyclic compounds such as guanine, purines and pyrimidines.

General Description

Corrosion inhibition and adsorption characteristics of 5-amino-4-imidazolecarboxamide hydrochloride on aluminum in 1M HCl has been investigated.

Synthesis

47 g of sodium nitrite was dissolved in 1.2 liters of water; The solution was cooled to 0° C. 100 g of 5-aminoimidazole-4 carboxamide was dissolved in a solution of hydrochloric acid (80 ml of 36% HCL in 720 ml water) with stirring. The resultant 5-aminoimidazole-4 carboxamide hydrochloride solution was added slowly, drop-wise, over 20-30 minutes at 0-5° C. After the addition was completed, the reaction mixture was stirred for 10 minutes and filtered. The solid obtained was suspended in 400 ml DM water and stirred for 15 minutes. The suspension was filtered and suction-dried for 15 minutes. The obtained solid was suspended in 500 ml of THF and stirred for 15 minutes. The suspension was filtered and suction-dried for 15 minutes. Finally, the solid was dried at 45° C. to afford 4-Amino-5-imidazolecarboxamide hydrochloride.

Purification Methods

Recrystallise the hydrochloride from EtOH. [Kuroda & Hakko JEst(1) Est(2)Heterocycl Chem 30 593 1993, Alhede et al. J Org Chem 56 2139 1991, Cheru et al. Heterocycles 24 1133 1992, Beilstein 25 II 221, 25 III/IV 4329.]

4-Amino-5-imidazolecarboxamide hydrochloride Preparation Products And Raw materials

Raw materials

carbanilic acid Acetamide

Preparation Products

More
Less

4-Amino-5-imidazolecarboxamide hydrochloride Suppliers

Americas 1 Belgium 2 Canada 1 China 316 Europe 3 Germany 6 India 41 Italy 1 Japan 5 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 2 United Kingdom 16 United States 44 Global 443
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Interchem Corporation USA
Tel
--
Fax
--
Email
esa@interchem.com
Country
United States
ProdList
469
Advantage
58
CHEM-IS-TRY Inc.,
Tel
--
Fax
--
Country
United States
ProdList
190
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
CHEM-IS-TRY, Inc.
Tel
--
Fax
--
Email
sales@chem-is-try.com
Country
United States
ProdList
551
Advantage
56
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Sphinx Scientific Laboratory, LLC
Tel
--
Fax
--
Email
sales@sphinxscientificlab.com
Country
United States
ProdList
3343
Advantage
50
VARDA Biotech (P) Ltd.
Tel
--
Fax
--
Email
vijay@vardabiotech.com
Country
United States
ProdList
208
Advantage
66
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
AB Chem Technologies, LLC
Tel
--
Fax
--
Email
sales@abchemtech.com
Country
United States
ProdList
1101
Advantage
46
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
TimTec Corporation
Tel
--
Fax
--
Email
info@timtec.net
Country
United States
ProdList
6891
Advantage
68
Research Organics Inc.
Tel
--
Fax
--
Email
info@resorg.com
Country
United States
ProdList
1324
Advantage
72
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Davos Chemical Corporation
Tel
--
Fax
--
Email
info@davos.com
Country
United States
ProdList
1640
Advantage
65
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
More
Less

View Lastest Price from 4-Amino-5-imidazolecarboxamide hydrochloride manufacturers

airuikechemical co., ltd.
Product
4-Amino-5-imidazole carboxamide hydrochloride 72-40-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Amino-5-Imidazolecarboxamide Hydrochloride 72-40-2
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2024-08-23
Shanghai Joiny Pharmaceutical Co.,LTD
Product
4-Amino-5-imidazolecarboxamide hydrochloride 72-40-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98.5%
Supply Ability
500kg
Release date
2022-09-30

72-40-2, 4-Amino-5-imidazolecarboxamide hydrochlorideRelated Search:

N,N-Dimethylformamide Glycine AMINOGUANIDINE HYDROCHLORIDE Aminoacetonitrile hydrochloride D-Glucosamine hydrochloride ALTRENOGEST Topotecan hydrochloride Formamide 4-Aminoimidazole Chlorantraniliprole 3-amino-3-iminopropanamide 2-FORMAMIDINO-2-PHENYLDIAZOACETAMIDE HYDROCHLORIDE 4-AMINO-5-IMIDAZOLECARBOXAMIDE 7-(2-CHLOROETHYL)THEOPHYLLINE 8-Chlorotheophylline Dimenhydrinate Imidazole 1-(3-CHLOROPROPYL)THEOBROMINE

  • 5-amino-4-imidazolecarboxamide hydrochloride (intermediate of dacarbazine)
  • 5-Amino-1H-imidazole-4-carboxamide hydrochloride 98%
  • 5-amino-1H-imidazole-4-carboxamide HCl
  • 4-Amino-5-(aminocarbonyl)imidazole Hydrochloride
  • 4-AMINO-5-IMIDAZOLECARBOXAMIDE HCL, (AICA) 98+%
  • 4-AMINO-5-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE 99%
  • 4-Amino-5-imidazolecarboxamide hydrochloride ,99%
  • 4-Amino-5-imidazolecarboxamide hydrochloride,98%
  • Dacarbazine Related Compound A (50 mg) (5-aminoimidazole-4-carboxamide hydrochloride)
  • 4-amino-1H-imidazole-5-carboxamide HCL
  • Dacarbazine Related CoMpound A
  • 5-AMino-3H-iMidazole-4-carboxylic acid aMide hydrochloride
  • 5-AMONO-4-IMIDAZOLE CARBOXAMIDE HYDROCHLORIDE
  • AMino - 4-5 - iMidazole carboxaMide hydrochloride
  • 5(4)-AMINO-4(5)-(AMINOCARBONYL)IMIDAZOLE HYDROCHLORIDE
  • 5(4)-AMINO-4(5)-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
  • 5(4)-AMINOIMIDAZOLE-4(5)-CARBOXAMIDE HYDROCHLORIDE
  • 5-AMINO-4-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
  • 5-AMINOIMIDAZOLE-4-CARBOXAMIDE HYDROCHLORIDE
  • 5-AMINO-3H-IMIDAZOLE-4-CARBOXYLIC ACID AMIDE HCL
  • 4-AMINO-1H-IMIDAZOLE-5-CARBOXAMIDE HYDROCHLORIDE
  • 4-AMINO-5-IMIDAZOLECARBOXAMIDE HCL
  • 4-AMINO-5-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
  • 4-AMINO-5-CARBOXAMIDO IMIDAZOLE HCL
  • 4(5)-AMINO-5(4)-IMIDAZOLECARBOXAMIDE HYDROCHLORIDE
  • 4-AMINOIMIDAZOLE-5-CARBOXAMIDE HYDROCHLORIDE
  • 4-Aminoimidazole-5-carboxamidehydrochloride,98%
  • 5-Amino-4-imidazolecarboxamide hydrochloride 98%
  • Imidazole-4-carboxamide, 5-amino-, monohydrochloride
  • AICA
  • AICA HCL
  • AICA HYDROCHLORIDE
  • N-(4-Amino-1H-imidazol-5-yl)formamidehydrochloride
  • TIMTEC-BB SBB003938
  • 4-Amino-5-carbamoylimidazole salt of hydrochloric acid
  • 5-aminoimidazole-4-carboxamide HCl
  • 5-amino-1H-imidazole-4-carboxamide monohydrochloride
  • 4-Amino-5-imidazolecarboxamide hydrochloride;AICA
  • 5-Amino-1H-imidazole-4-carboxamide hydrochloride
  • 5-Aminoindazole-4-Carboxyamide Hydrochloride
  • 5-Amino-4-imidazolecarboxamide hydrochloride, 98
  • 4(5)-Amino-5(4)-Imidazolecarboxamide HCl
  • LABOTEST-BB LT00440910
  • Temozolomide intermediate
  • 5-amino-1h-imidazole-4-carboxamidmonohydrochloride
  • 5-Aminoimidazol-4-carboxamide, hydrochloride
  • 5-Imidazolecarboxamide, 4-amino-, hydrochloride
  • AIC .cntdot. HCl
  • 1H-Imidazole-4-carboxamide, 5-amino-, monohydrochloride
  • 4-Amino-5-carboxamido imidazole hydrochloride
  • 4-amino-5-imidazolecarboxamidhydrochloride
  • 4-Aminoimidazole-5-carboxamide hydrochoride
  • Dacarbazine EP Impurity B(USP RC A)
  • imidazolecarboxamide hydrochloride
  • 5(4)-Amino-4(5)-(aminocarbonyl)imidazole Hydrochloride &gt
  • Dacarbazine EP Impurity B
  • 5-Amino-1H-imidazoL
  • e-4-carboxamide hydrochL