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Bromo-PEG5-t-butyl ester

Product Name
Bromo-PEG5-t-butyl ester
CAS No.
1415800-38-2
Chemical Name
Bromo-PEG5-t-butyl ester
Synonyms
Br-PEG5-COOtBu;Bromo-PEG5-Boc;CAS_1415800-38-2;Br-PEG5-butyl ester;Br-PEG5-CH2CH2COOtBu;Br-PEG5-t-butyl ester;Bromo-PEG5-tert-butyl Ester;tert-Butyl 1-bromo-3,6,9,12,15-pentaoxaoctadecan-18-oate;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-bromo-, 1,1-dimethylethyl ester;tert-butyl 3-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CBNumber
CB53062451
Molecular Formula
C17H33BrO7
Formula Weight
429.34
MOL File
1415800-38-2.mol
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Bromo-PEG5-t-butyl ester Property

Boiling point:
453.9±40.0 °C(Predicted)
Density 
1.200±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM,DMF
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B681655
Product name
Bromo-PEG5-t-butylEster
Packaging
5mg
Price
$45
Updated
2021/12/16
BroadPharm
Product number
BP-21011
Product name
Bromo-PEG5-t-butylester
Purity
98%
Packaging
250mg
Price
$380
Updated
2021/12/16
BroadPharm
Product number
BP-21011
Product name
Bromo-PEG5-t-butylester
Purity
98%
Packaging
500mg
Price
$560
Updated
2021/12/16
Activate Scientific
Product number
AS104015
Product name
Br-PEG5-CH2CH2COOtBu
Purity
95+%
Packaging
1g
Price
$673
Updated
2021/12/16
BroadPharm
Product number
BP-21011
Product name
Bromo-PEG5-t-butylester
Purity
98%
Packaging
1g
Price
$980
Updated
2021/12/16
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Bromo-PEG5-t-butyl ester Chemical Properties,Usage,Production

Description

Bromo-PEG5-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Bromo-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG5-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG5-t-butyl ester Suppliers

China 57 India 1 United States 3 Global 61
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from Bromo-PEG5-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Br-PEG5-COOtBu 1415800-38-2
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25
Career Henan Chemical Co
Product
Bromo-PEG5-t-butyl ester 1415800-38-2
Price
US $2.00/g
Min. Order
1g
Purity
95~99.9%
Supply Ability
5KG
Release date
2020-03-05

1415800-38-2, Bromo-PEG5-t-butyl esterRelated Search:

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  • Br-PEG5-COOtBu
  • 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-bromo-, 1,1-dimethylethyl ester
  • Br-PEG5-CH2CH2COOtBu
  • Br-PEG5-butyl ester
  • Br-PEG5-t-butyl ester
  • CAS_1415800-38-2
  • Bromo-PEG5-Boc
  • tert-Butyl 1-bromo-3,6,9,12,15-pentaoxaoctadecan-18-oate
  • Br-PEG5-CH2CH2COOtBu/4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-bromo-, 1,1-dimethylethyl ester
  • tert-butyl 3-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • Bromo-PEG5-tert-butyl Ester
  • 1415800-38-2