Uses
ChemicalBook > CAS DataBase List > 4-Chloro-3-fluoroaniline

4-Chloro-3-fluoroaniline

Uses
Product Name
4-Chloro-3-fluoroaniline
CAS No.
367-22-6
Chemical Name
4-Chloro-3-fluoroaniline
Synonyms
BUTTPARK 44\01-97;Gefitinib Impurity 96;Fluoro-4-chloroaniline;4-Chloro-3-fluoroanline;3-FLUORO-4-CHLOROANILINE;4-CHLORO-3-FLUOROANILINE;4-Chloro-3-fluoroaniline98%;4-Chloro-3-fluoroaniline >4-Chloro-3-fluoroaniline 98%;4-chloro-3-fluorobenzenaMine
CBNumber
CB5343050
Molecular Formula
C6H5ClFN
Formula Weight
145.56
MOL File
367-22-6.mol
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4-Chloro-3-fluoroaniline Property

Melting point:
61
Boiling point:
226°C(lit.)
Density 
1.349±0.06 g/cm3(Predicted)
Flash point:
60 - 62°C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.94±0.10(Predicted)
color 
White to Gray to Red
BRN 
2716278
CAS DataBase Reference
367-22-6(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36/37/39-63-45-38
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
779970
Product name
4-Chloro-3-fluoroaniline
Purity
≥97.0% (GC)
Packaging
5g
Price
$66.4
Updated
2023/06/20
TCI Chemical
Product number
C2512
Product name
4-Chloro-3-fluoroaniline
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$51
Updated
2024/03/01
TCI Chemical
Product number
C2512
Product name
4-Chloro-3-fluoroaniline
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$201
Updated
2024/03/01
Alfa Aesar
Product number
H26148
Product name
4-Chloro-3-fluoroaniline, 99%
Packaging
1g
Price
$72.65
Updated
2024/03/01
Alfa Aesar
Product number
H26148
Product name
4-Chloro-3-fluoroaniline, 99%
Packaging
250mg
Price
$42.4
Updated
2021/12/16
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4-Chloro-3-fluoroaniline Chemical Properties,Usage,Production

Uses

4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate; a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase. 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540) which is an impurity of the tyrosine kinase inhibitor Gefitinib.

Chemical Properties

White to light yellow solid

Uses

4-Chloro-3-fluoroaniline is used in the synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate

4-Chloro-3-fluoroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-3-fluoroaniline Suppliers

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View Lastest Price from 4-Chloro-3-fluoroaniline manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Chloro-3-fluoroaniline 367-22-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Shaanxi Dideu Medichem Co. Ltd
Product
4-Chloro-3-fluoroaniline 367-22-6
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-17
Anhui Zhongda Biotechnology Co., Ltd
Product
4-Chloro-3-fluoroaniline 367-22-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100tons
Release date
2023-10-26

367-22-6, 4-Chloro-3-fluoroanilineRelated Search:

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