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Boc-Hyp-OH

Product Name
Boc-Hyp-OH
CAS No.
13726-69-7
Chemical Name
Boc-Hyp-OH
Synonyms
(2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid;BOC-HYP-OH;BOC-HYP;BOC-L-HYP-OH;N-BOC-L-HYDROXYPROLINE;(4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline;(2S,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylic Acid;N-ter;Teneint-E;oc-L-Hyp-OH
CBNumber
CB5411793
Molecular Formula
C10H17NO5
Formula Weight
231.25
MOL File
13726-69-7.mol
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Boc-Hyp-OH Property

Melting point:
123-127 °C(lit.)
alpha 
-78 º (in H2O)
Boiling point:
390.9±42.0 °C(Predicted)
Density 
1.312±0.06 g/cm3(Predicted)
refractive index 
-68 ° (C=1, MeOH)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.80±0.40(Predicted)
form 
Powder
color 
White to off-white
optical activity
[α]20/D 53.5±2°, c = 1% in DMF
Water Solubility 
very faint turbidity
BRN 
4295484
InChIKey
BENKAPCDIOILGV-RQJHMYQMSA-N
CAS DataBase Reference
13726-69-7(CAS DataBase Reference)
EPA Substance Registry System
(2S,4R)-1-tert-Butyl 4-hydroxy-1,2-pyrrolidinecarboxylate (13726-69-7)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2933 99 80
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.53026
Product name
Boc-Hyp-OH (cryst)
Purity
Novabiochem?
Packaging
25g
Price
$344
Updated
2024/03/01
Sigma-Aldrich
Product number
8.53026
Product name
Boc-Hyp-OH (cryst)
Purity
Novabiochem?
Packaging
100g
Price
$1030
Updated
2024/03/01
Sigma-Aldrich
Product number
15544
Product name
Boc-Hyp-OH
Purity
≥98.0% (TLC)
Packaging
5g
Price
$36.6
Updated
2024/03/01
Sigma-Aldrich
Product number
15544
Product name
Boc-Hyp-OH
Purity
≥98.0% (TLC)
Packaging
25g
Price
$150
Updated
2024/03/01
TCI Chemical
Product number
B1635
Product name
trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline
Purity
>98.0%(T)
Packaging
5g
Price
$18
Updated
2024/03/01
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Boc-Hyp-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Boc-Hyp-OH is used in the preparation of hydroxyproline derivatives. It is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.

Biological Activity

Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Boc-Hyp-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-Hyp-OH Suppliers

future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
BTC Pharmaceutical CO. Ltd
Tel
0513-0513-68015397 18862996710
Fax
0513-68015394
Email
sales12@btcpharm.com
Country
China
ProdList
692
Advantage
55
GenChem & GenPharm (Changzhou) Co., Ltd.
Tel
0519-85720003 18861157602
Fax
0519-85720007
Email
sales03@genchem.cn
Country
China
ProdList
111
Advantage
58
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375892 15562613975
Email
3416953599@qq.com
Country
China
ProdList
309
Advantage
58
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
347
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
451
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from Boc-Hyp-OH manufacturers

Wuhan Fortuna Chemical Co.,Ltd
Product
boc-L-hydroxyproline 13726-69-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-08-26
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Boc-L-Hydroxyproline 13726-69-7
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%HPLC
Supply Ability
10 Tons
Release date
2021-06-16
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Boc-Hyp-OH 13726-69-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-24

13726-69-7, Boc-Hyp-OHRelated Search:


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