Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine

Product Name: Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine
CAS No.: 607366-20-1
Chemical Name: Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine
Synonyms: FMOC-DAP(IVDDE)-OH;FMOC-DPR(IVDDE)-OH;FMOC-L-DAP(IVDDE)-OH;N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1;Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine;3-[1-(4,4-DiMethyl-2,6-dioxocyclohexylidene)-3-MethylbutylaMino]-FMoc-L-alanine, 95%;Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine USP/EP/BP;FMoc-Nβ-(4,4-diMethyl-2,6-dioxocyclohex-1-ylidene)-3-Methylbutyl-L-2,3-diaMinopropionic acid;Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid;FMOC-N-BETA-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL-L-2,3-DIAMINOPROPIONIC ACID
CBNumber: CB5413560
Molecular Formula: C31H36N2O6
Formula Weight: 532.63
MOL File: 607366-20-1.mol

More

Less

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Property

Boiling point:: 733.7±60.0 °C(Predicted)
Density: 1.221
storage temp.: Store at -15°C to -25°C.
pka: 3.47±0.10(Predicted)
form: powder
Appearance: White to off-white Solid

More

Less

Safety

HS Code: 2924297099

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52083
Product name: Fmoc-Dpr(ivDde)-OH
Purity: Novabiochem?
Packaging: 1G
Price: $157
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52083
Product name: Fmoc-Dpr(ivDde)-OH
Purity: Novabiochem?
Packaging: 5G
Price: $512.4
Updated: 2025/07/31

TRC

Product number: F621080
Product name: N-α-Fmoc-N-β-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionicAcid
Packaging: 250mg
Price: $75
Updated: 2021/12/16

TRC

Product number: F621080
Product name: N-α-Fmoc-N-β-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionicAcid
Packaging: 1g
Price: $335
Updated: 2021/12/16

Activate Scientific

Product number: AS89969
Product name: Fmoc-Dap(ivDde)-OH
Purity: 95%
Packaging: 1g
Price: $293
Updated: 2021/12/16

More

Less

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Chemical Properties,Usage,Production

Uses

N-alpha-Fmoc-N-beta-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic Acid is used in the synthesis of phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors. It is also used to prepare peptidomimetic ligands for α4β1 integrin on Jurkat T-leukemia cells.

General Description

This orthogonally-protected diaminopropionic acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1]. However, migration from side-chain to the unprotected α-amino group of Dpr is unavoidable [2]. This side-reaction can, however, be minimized by the appropriate choice of coupling method for the subsequent residue, see [3].

When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [4].

The product number for this product was previously 04-12-1195.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Suppliers

China 71 Germany 3 India 1 Japan 4 United Kingdom 1 United States 9 Global 89

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alabiochem Tech.Co., Ltd.

Tel: 512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 970
Advantage: 59

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

Dtchem Laboratories,（Gan Su）Co.,Ltd.

Tel: 18993966060
Fax: 0943-8288977
Email: sales@techbiochem.com
Country: China
ProdList: 806
Advantage: 61

ShenZhen InnoSyn Biotech Co.,Ltd

Tel: 0755-28351685 18503098468
Fax: +86-755-28466854
Email: innosyn@163.com
Country: China
ProdList: 602
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

607366-20-1, Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanineRelated Search:

Fmoc-O-trityl-L-serine Dimethyl sulfide Dimethyl ether D-Alanine p-Anisaldehyde p-Anisidine 3-(METHOXYMETHOXY)BENZALDEHYDE Dacthal Phenprobamate (Trifluoromethoxy)benzene ETHANE EC 2.6.1.2 4-Methoxyphenylacetic acid N,N-Dimethylformamide Dimethyl carbonate Fmoc-8-amino-3,6-dioxaoctanoic acid Dimethyl sulfate Dimethyl sulfoxide

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-BETA-(1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL)-L-2,3-DIAMINOPROPIONIC ACID

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-BETA-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL]-L-2,3-DIAMINOPROPIONIC ACID

N-ALPHA-FMOC-N-BETA-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL-L-DIAMINOPROPIONIC ACID

3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

FMOC-N-BETA-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)-3-METHYLBUTYL-L-2,3-DIAMINOPROPIONIC ACID

FMOC-DPR(IVDDE)-OH

FMOC-DAP(IVDDE)-OH

FMOC-L-DAP(IVDDE)-OH

(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutylamino)propanoic acid

N2-Fmoc-N3-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid

FMoc-Nβ-(4,4-diMethyl-2,6-dioxocyclohex-1-ylidene)-3-Methylbutyl-L-2,3-diaMinopropionic acid

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine

3-[1-(4,4-DiMethyl-2,6-dioxocyclohexylidene)-3-MethylbutylaMino]-FMoc-L-alanine, 95%

Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid

(2S)-3-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

L-Alanine, 3-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine USP/EP/BP

N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1

(S)-2-(Fmoc-amino)-3-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]propanoic Acid

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl)amino)propanoic acid - [F91501]

607366-20-1

amino acid

amino acids