Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine
- Product Name
- Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine
- CAS No.
- 607366-20-1
- Chemical Name
- Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine
- Synonyms
- FMOC-DAP(IVDDE)-OH;FMOC-DPR(IVDDE)-OH;FMOC-L-DAP(IVDDE)-OH;N-α-Fmoc-N-β-1-(4,4-dimethyl-2,6-dioxocyclohex-1;Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine;3-[1-(4,4-DiMethyl-2,6-dioxocyclohexylidene)-3-MethylbutylaMino]-FMoc-L-alanine, 95%;Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine USP/EP/BP;FMoc-Nβ-(4,4-diMethyl-2,6-dioxocyclohex-1-ylidene)-3-Methylbutyl-L-2,3-diaMinopropionic acid;Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid;Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic acid
- CBNumber
- CB5413560
- Molecular Formula
- C31H36N2O6
- Formula Weight
- 532.63
- MOL File
- 607366-20-1.mol
Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Property
- Boiling point:
- 733.7±60.0 °C(Predicted)
- Density
- 1.221
- storage temp.
- Store at -15°C to -25°C.
- pka
- 3.47±0.10(Predicted)
Safety
- HS Code
- 2924297099
N-Bromosuccinimide Price
- Product number
- 8.52083
- Product name
- Fmoc-Dpr(ivDde)-OH
- Purity
- Novabiochem?
- Packaging
- 1G
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 8.52083
- Product name
- Fmoc-Dpr(ivDde)-OH
- Purity
- Novabiochem?
- Packaging
- 5G
- Price
- $713
- Updated
- 2024/03/01
- Product number
- F621080
- Product name
- N-α-Fmoc-N-β-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionicAcid
- Packaging
- 1g
- Price
- $335
- Updated
- 2021/12/16
- Product number
- F621080
- Product name
- N-α-Fmoc-N-β-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionicAcid
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 07105
- Product name
- Nα-Fmoc-Nβ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionicacid,98-100%(Assaybytitration)
- Purity
- 98-100%(Assaybytitration)
- Packaging
- 250MG
- Price
- $95.76
- Updated
- 2021/12/16
Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Chemical Properties,Usage,Production
Uses
N-alpha-Fmoc-N-beta-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-2,3-diaminopropionic Acid is used in the synthesis of phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors. It is also used to prepare peptidomimetic ligands for α4β1 integrin on Jurkat T-leukemia cells.
General Description
This orthogonally-protected diaminopropionic acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1]. However, migration from side-chain to the unprotected α-amino group of Dpr is unavoidable [2]. This side-reaction can, however, be minimized by the appropriate choice of coupling method for the subsequent residue, see [3].
When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [4].
The product number for this product was previously 04-12-1195.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-3-[[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-L-alanine Suppliers
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 0512-58900862 400-0707518
- Fax
- 0086-512-56765862
- sales@alabiochem.com
- Country
- China
- ProdList
- 995
- Advantage
- 59
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15402
- Advantage
- 60
- Tel
- +1 (888) 615-9178 / (561) 791-8787
- Fax
- +1 (561) 791-8728
- service@chempep.com
- Country
- United States
- ProdList
- 2138
- Advantage
- 57
- Tel
- 0755-28351685 18503098468
- Fax
- +86-755-28466854
- innosyn@163.com
- Country
- China
- ProdList
- 600
- Advantage
- 55
- Tel
- 028-84502008 13568869383
- Fax
- 028-66476329
- sales@hygeiapharm.com
- Country
- China
- ProdList
- 297
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 0571-+86-571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 11481
- Advantage
- 59