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MERBROMIN

Product Name
MERBROMIN
CAS No.
129-16-8
Chemical Name
MERBROMIN
Synonyms
domf;Emcerol;flavurol;Chromine;Ekakrome;Hg2sb2o7;MERBROMIN;Marbromin;mercurome;Brocasept
CBNumber
CB5424818
Molecular Formula
C20H11Br2HgNaO6
Formula Weight
730.69
MOL File
129-16-8.mol
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MERBROMIN Property

Melting point:
≥300 °C
storage temp. 
Poison room
solubility 
Water : ≥ 50 mg/mL (66.43 mM);DMSO : 6.67 mg/mL (8.86 mM)
form 
crystalline
color 
green
Odor
Odorless
PH Range
8.5 - 9
Water Solubility 
2.561g/L at 25℃
Merck 
13,5892
Stability:
Stable. Incompatible with strong oxidizing agents, strong acids.
LogP
1.418 at 25℃
CAS DataBase Reference
129-16-8(CAS DataBase Reference)
EPA Substance Registry System
Mercury, (2',7'-dibromo-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-4'-yl)hydroxy-, disodium salt (129-16-8)
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Safety

Hazard Codes 
T+,N
Risk Statements 
26/27/28-33-50/53
Safety Statements 
13-28-36-45-60-61
RIDADR 
UN 2025 6.1/PG 2
WGK Germany 
3
RTECS 
LM5250000
HazardClass 
6.1(a)
PackingGroup 
II
Hazardous Substances Data
129-16-8(Hazardous Substances Data)
Toxicity
mouse,LD50,intravenous,50mg/kg (50mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 43, Pg. 645, 1931.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M7011
Product name
Mercury dibromofluorescein disodium salt
Purity
practical grade, crystalline
Packaging
10g
Price
$54.6
Updated
2023/01/07
Sigma-Aldrich
Product number
M7011
Product name
Mercury dibromofluorescein disodium salt
Purity
practical grade, crystalline
Packaging
25g
Price
$73.2
Updated
2023/01/07
Usbiological
Product number
281568
Product name
Mercurochrome
Packaging
10g
Price
$360
Updated
2021/12/16
ChemScene
Product number
CS-4443
Product name
Merbromin
Packaging
1g
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-4443
Product name
Merbromin
Packaging
500mg
Price
$50
Updated
2021/12/16
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MERBROMIN Chemical Properties,Usage,Production

Chemical Properties

dark green solid

Originator

Mercurin,Monik

Uses

anthelmintic

Uses

Antiseptic and applied topically

Definition

ChEBI: An organic sodium salt that is 2,7-dibromo-4-hydroxymercurifluorescein in which the carboxy group and the phenolic hydroxy group have been deprotonated and the resulting charge is neutralised by two sodium ions.

Manufacturing Process

49 g 2,7-dibromofluorescein are dissolved in a solution of 8 g of sodium hydroxide in 50 ml of water, and diluted to 200 ml 12.5 ml of glacial acetic acid are added to this solution with stirring. A homogeneous pasty precipitate results with vigorously stirring. A filtered solution of about 22.5 g of mercuric oxide in 25 ml of glacial acid and 50 ml water, diluted after solution to 100 ml, is then added to the suspended precipitate, and the whole diluted to about 500 ml. The mixture is boiled until a small portion of filtered solution gives no test for mercury when treated with ammonium sulfide, the approximate time required for this operation being about 4.5-6 hours. As the boiling continues the precipitate become darker in color and more granular. It is washed, preferably by centrifuging, to remove acetic acid and sodium acetate, and dried at about 110°C. By close adherence to above conditions an almost quantitative yield may be secured. The product may be regarded as consisting essentially of 2,7-dibromo-4-hydroxymercuryfluorescein, resulting from substantially complete hydrolysis of an acetoxy-mercury compound, which probably formed as an intermediate. It is red powder, which is insoluble in the usual solvents but dissolves in two equivalents of sodium hydroxide yielding a deep cherry-red solution. The solution has the tendency to decomposition on long standing.

Therapeutic Function

Antiseptic

Hazard

Toxic by ingestion.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intravenous and subcutaneous routes. Mutation data reported. Relatively nonirritating and nontoxic to damaged skin or tissue. A topical antiseptic. An FDA over-the-counter drug. When heated to decomposition it emits very toxic fumes including fumes of Na2O, Br-, and Hg. See also MERCURY COMPOUNDS, ORGANIC.

Purification Methods

The Na salt is dissolved in the minimum volume of H2O, or the free acid suspended in H2O and dilute NaOH is added to cause it to dissolve, filter and acidify it with dilute HCl. Collect the precipitate, wash it with H2O by centrifugation and dry it in a vacuum. The di Na salt can be purified by dissolving it in the minimum volume of H2O and is precipitated by adding EtOH, filter, wash it with EtOH or Me2CO and dry it in a vacuum. Its solubility in 95% EtOH is 2% and in MeOH it is 16%. [White J Am Chem Soc 42 2355 1920.]

MERBROMIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from MERBROMIN manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
MERBROMIN 129-16-8
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-09-06
Dideu Industries Group Limited
Product
MERBROMIN 129-16-8
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-21

129-16-8, MERBROMINRelated Search:


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  • asceptichrome
  • aseptichrome
  • chromargyre
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  • disodium2’,7’-dibromo-4’-(hydroxymercury)fluorescein
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  • gallochrome
  • gynochrome
  • merbromin(mercurochrome)
  • Merbromin (Mercury dibromofluorescein disodium salt)
  • SODIUM DIBROMOXYMERCURIFLUORESCEIN
  • SODIUM OXYMERCURIDIBROMOFLUORESCEIN
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  • MERCURY DIBROMOFLUORESCEIN
  • MERCURICHROME
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  • Mercurochrome(MercuryDibromofluorescein)
  • MerbrominN.F
  • MercurochromeGranulars
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  • Dibromohydroxymercurifluorescein, disodium salt
  • Mercurochrome, 24-27% Mercury
  • mercuranine
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  • mercurocol
  • mercurome
  • mercurophage
  • mercury,(2’,7’-dibromo-3’,6’-dihydroxy-3-oxospiro[isobenzofuran-1(3h),9’-[9h]x
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  • DISODIUM27DIBROMO4HYDROXYMERCURIFLUORESCEIN
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  • MERCUROCHROME/MERBROMIN
  • Merbromin, Mercurochrome, 2μ,7μ-Dibromo-5μ-(hydroxymercurio)fluorescein disodium salt
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  • MERCUROCHROME Extra Pure
  • ZP 1,inhibit,ZP-1,ZP1,Mercury dibromofluorescein disodium,Inhibitor,Merbromin,Bacterial
  • Mercurochrome Liquid