Methyl 6-bromo-2-naphthoate

Product Name: Methyl 6-bromo-2-naphthoate
CAS No.: 33626-98-1
Chemical Name: Methyl 6-bromo-2-naphthoate
Synonyms: methyl 6-bromonaphthalene-2-carboxylate;Adap-int B;ADAPALENE RC A;Adapalene IMpurity G;Methyl 6-bromo-2-nap;Adapalene Impurity 4;6-BROMO-2-NAPHTHOIC AICD;Methyl-6-Bromo-2-Naphtoat;Methyl-6-bromo-2-naphtoate;6-Bromo-2-methyl napthoate
CBNumber: CB5426069
Molecular Formula: C12H9BrO2
Formula Weight: 265.1
MOL File: 33626-98-1.mol

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Methyl 6-bromo-2-naphthoate Property

Melting point:: 123-126 °C (lit.)
Boiling point:: 357.0±15.0 °C(Predicted)
Density: 1.492±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Crystalline Powder
color: Off-white to cream or light brown
BRN: 2578943
InChIKey: JEUBRLPXJZOGPX-UHFFFAOYSA-N
CAS DataBase Reference: 33626-98-1(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 20/21/22-34
Safety Statements: 24/25-45-36/37/39-27-26
WGK Germany: 3
HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2827
Product name: Adapalene Related Compound A
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 100MG
Price: $608
Updated: 2024/03/01

Sigma-Aldrich

Product number: 539406
Product name: Methyl 6-bromo-2-naphthoate
Purity: 98%
Packaging: 5g
Price: $29.52
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1011710
Product name: Adapalene Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1300
Updated: 2024/03/01

TCI Chemical

Product number: B2202
Product name: Methyl 6-Bromo-2-naphthoate
Purity: >98.0%(GC)
Packaging: 5g
Price: $51
Updated: 2024/03/01

TCI Chemical

Product number: B2202
Product name: Methyl 6-Bromo-2-naphthoate
Purity: >98.0%(GC)
Packaging: 25g
Price: $201
Updated: 2024/03/01

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Methyl 6-bromo-2-naphthoate Chemical Properties,Usage,Production

Chemical Properties

Pale yellow or light brown powder

Uses

Methyl 6-Bromo-2-napthoate (Adapalene USP Related Compound A) is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.

Uses

Methyl 6-bromo-2-naphthoate may be used to synthesize:

6-vinyl-2-naphthalencarbaldehyde
methyl 6-(3-tert-butyl-4-methoxyphenyl)-2-naphthoate
methyl 6-[3-tert-butyl-4-[(tert-butyldiethylsilyl)oxy]-phenyl]-2-naphthoate
methyl 6-[3-(1-adamantyl)-4-[(tert-butyldimethylsilyl)-oxy]phenyl]-2-naphthoate
methyl 6-[3-(1-adamantyl)-4-[[(2,3-dimethyl-1,3-dioxolan-4-yl)methylloxy]phenyl]-2-naphthoate
2-bromo-6-(bromomethyl)naphthalene

Uses

Methyl 6-Bromo-2-napthoate is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.

General Description

Methyl 6-bromo-2-naphthoate undergoes aromatic Finkelstein reaction followed by hydrolysis to afford 6-iodo-2-naphthoic acid.

Methyl 6-bromo-2-naphthoate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl 6-bromo-2-naphthoate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Methyl 6-bromo-2-naphthoate 33626-98-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-26

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 6-bromo-2-naphthoate 33626-98-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-14

Career Henan Chemical Co

Product: Methyl 6-bromo-2-naphthoate 33626-98-1
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

33626-98-1, Methyl 6-bromo-2-naphthoateRelated Search:

6-BROMO-4-INDAZOLECARBOXYLIC ACID METHYL ESTER 1-(5-Bromo-2-methoxy-phenyl)adamantane 1-Adamantanol Hydroxy Adapalene METHYL 6-OXO-1,6-DIHYDRO-3-PYRIDINECARBOXYLATE Methyl 6-bromonicotinate METHYL 6-FORMYLNICOTINATE methyl 6-chloropyrimidine-4-carboxylate Methyl 6-bromoisoquinoline-1-carboxylate Methyl 6-bromohexanoate Methyl 6-chloronicotinate 6-CHLORO-2-PICOLINIC ACID METHYL ESTER METHYL 6-CHLOROPYRIDAZINE-3-CARBOXYLATE methyl 6-methylpyridine-2-carboxylate 6-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 6-METHYLPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER 2-Chloro-6-pyrazinecarboxylic acid methyl ester Methyl 6-HydroxypyriMidine-4-carboxylate

6-Bromo-2-Naphtoic Acid Methyl Ester

2-Bromo-6-naphthoic acid methylester

6-BROMO-2-NAPHTHALENECARBOXYLIC ACID METHYL ESTER

6-BROMO-2-NAPHTHOIC ACID METHYL ESTER

METHYL 6-BROMO-2-NAPHTHALENECARBOXYLATE

METHYL 6-BROMO-2-NAPHTHOATE

2-Naphthoic acid, 6-bromo, methyl ester

Methyl-6-bromo-2-naphtoate

6-BROMO-2-NAPHTHOIC AICD

6-BROMO-2-NAPHTHOIC AICD, METHYL ESTER

Adapalene Impurity G (USP RC A)

6-Bromo-2-methyl napthoate

Adapalene USP Related Compound A

6-Bromonaphthalene-2-carboxylic acid methyl ester

Methyl 6-bromo-2-naphthoate,98%

Adapalene Related CoMpound A

Methyl-6-Bromo-2-Naphtoat

6-Bromo-2-naphthalenecarboxylic Acid Methyl Ester 6-Bromo-2-naphthoic Acid Methyl Ester Methyl 6-Bromo-2-naphthalenecarboxylate

Adapalene IMpurity G

Methyl 6-bromo-2-nap

Adapalene Related Compound A (50 mg) (Methyl 6-bromo-2-naphthoate)

Methyl 6-broMo -2- napthoate

Methyl 6-broMo-2-naphthoate, 98% 5GR

Methyl 6-BroMo-2-naphthoate, 98.0%(GC)

methyl 6-bromonaphthalene-2-carboxylate

Adapalene Impurity 4

Adap-int B

Methyl 6-Bromo-2-naphthoate &gt

2-Naphthalenecarboxylic acid, 6-bromo-, methyl ester

Adapalene Impurity 12(Adapalene Related Compound A)

Methyl 6-bromo-2-naphthoate CAS:33626-98-1

Adapalene Related Compound A (Methyl 6-bromo-2-naphthoate) (1011710)

2-Naphthalenecarboxylic acid, 6-bromo-, methyl ester (9CI, ACI)

6-bromo-2-Naphthalenecarboxylic acid methyl ester (9CI ACI)

Methyl 6-bromo-2-naphthote

ADAPALENE RC A

33626-98-1

3626-98-1

BrC10H6CO2CH3

C12H9BrO2

Naphthalene series

Building Blocks

C12 to C63

Carbonyl Compounds

Chemical Synthesis

Organic Building Blocks

Others chemical reagents

C12 to C63

Carbonyl Compounds

Esters

API

Intermediates of Adapalene

Aromatic Esters

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

ADAPALENE

blocks

Bromides

Carboxes