Ethyl 6-amino-5-methoxyindole-2-carboxylate
- Product Name
- Ethyl 6-amino-5-methoxyindole-2-carboxylate
- CAS No.
- 107575-60-0
- Chemical Name
- Ethyl 6-amino-5-methoxyindole-2-carboxylate
- Synonyms
- 6-AMino-5-Methoxy indole-2-carboxylate;ETHYL 6-AMINO-5-METHOXYINDOLE-2-CARBOXYLATE;methyl 6-amino-5-methoxy-1H-indole-2-carboxylate;6-amino-5-methoxyindole-2-carboxylic acid ethyl ester;6-AMino-5-Methoxy-1H-indole-2-carboxylic Acid Ethyl Ester;1H-Indole-2-carboxylic acid, 6-amino-5-methoxy-, ethyl ester;Nicotine Intermediates Ethyl 6-amino-5-methoxyindole-2-carboxylate
- CBNumber
- CB5448948
- Molecular Formula
- C12H14N2O3
- Formula Weight
- 234.25
- MOL File
- 107575-60-0.mol
Ethyl 6-amino-5-methoxyindole-2-carboxylate Property
- Melting point:
- 164-166°C
- Boiling point:
- 439.3±40.0 °C(Predicted)
- Density
- 1.283±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- Soluble in dichloromethane, ethyl acetate and methanol.
- form
- Solid
- pka
- 15.95±0.30(Predicted)
- color
- Slightly Yellowish-Brown
Safety
- Risk Statements
- 33-36/37/38
- Safety Statements
- 26-37
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E898810
- Product name
- Ethyl6-Amino-5-methoxyindole-2-carboxylate
- Packaging
- 100mg
- Price
- $1175
- Updated
- 2021/12/16
- Product number
- 075676
- Product name
- Ethyl 6-amino-5-methoxyindole-2-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1750
- Updated
- 2021/12/16
- Product number
- CHM0151902
- Product name
- ETHYL-6-AMINO-5-METHOXYINDOLE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $1871.1
- Updated
- 2021/12/16
- Product number
- 9988
- Product name
- Ethyl6-Amino-5-methoxyindole-2-carboxylate
- Packaging
- 125mg
- Price
- $2120
- Updated
- 2021/12/16
- Product number
- 075676
- Product name
- Ethyl 6-amino-5-methoxyindole-2-carboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $639
- Updated
- 2021/12/16
Ethyl 6-amino-5-methoxyindole-2-carboxylate Chemical Properties,Usage,Production
Chemical Properties
Slightly Yellowish-Brown Solid
Uses
Ethyl 6-amino-5-methoxyindole-2-carboxylate is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.
Synthesis
119825-27-3
107575-60-0
The experimental procedure for the synthesis of ethyl 6-amino-5-methoxyindole-2-carboxylate using pyrroloquinoline impurity 1 as starting material was as follows: the experiment was divided into six groups, each using a different sample solution of heteropolyacid as catalyst. The procedure was as follows: compound 6 (0.524 g, 2 mmol) and benzylamine (0.321 g, 0.328 ml, 3 mmol) were placed in a 10 ml flask, and heteropolyacid ionic liquids (0.04 mmol) were added as catalysts, respectively. The reaction mixture was heated by microwave heating at 140 °C for 90 min. After completion of the reaction, 20 ml of ethyl acetate was added to the mixture and stirred thoroughly for 30 minutes. Subsequently, the mixture was filtered and the filtrate was concentrated to dryness by evaporation and finally purified by recrystallization to obtain the target product compound 7.
References
[1] Patent: CN104557921, 2018, B. Location in patent: Paragraph 0101-011
[2] Helvetica Chimica Acta, 1993, vol. 76, # 4, p. 1667 - 1673
[3] Patent: WO2006/102642, 2006, A1. Location in patent: Page/Page column 9; 15; 1/6
[4] Tetrahedron Letters, 1988, vol. 29, # 30, p. 3709 - 3712
Ethyl 6-amino-5-methoxyindole-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl 6-amino-5-methoxyindole-2-carboxylate Suppliers
- Tel
- --
- Fax
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- info@trc-canada.com
- Country
- Canada
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- 6038
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View Lastest Price from Ethyl 6-amino-5-methoxyindole-2-carboxylate manufacturers
- Product
- Ethyl 6-amino-5-methoxyindole-2-carboxylate 107575-60-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-13