DL-Tryptophan Property

Melting point:

289-290 °C (dec.)(lit.)

Boiling point:

342.72°C (rough estimate)

alpha 

[α]D20 -1～1°(c=1, dil. HCl)

Density 

1.1754 (rough estimate)

refractive index 

1.5200 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

methanol: water (7:3): soluble

form 

Powder

pka

2.30±0.10(Predicted)

color 

White to light beige or light yellow

Odor

Odorless

Water Solubility 

10 g/L (20 ºC)

BRN 

86196

Stability:

Stable. Incompatible with strong oxidizing agents, strong acids.

InChIKey

QIVBCDIJIAJPQS-UHFFFAOYSA-N

LogP

1.040 (est)

CAS DataBase Reference

54-12-6(CAS DataBase Reference)

NIST Chemistry Reference

Tryptophane(54-12-6)

EPA Substance Registry System

Tryptophan (54-12-6)

Safety

Hazard Codes 

Xi

Risk Statements 

22-36/37/38-37/38-41

Safety Statements 

24/25-36/37/39-36-26

WGK Germany 

1

RTECS 

YN6129200

F 

8

TSCA 

Yes

HS Code 

29339990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

DL-Tryptophan Chemical Properties,Usage,Production

Chemical Properties

White crystals. Slightly soluble in water; stable in alkaline solution; decomposed by strong acids.

Uses

DL-Tryptophan is an amino acid precursor of serotonin and melatonin. It is a dietary supplement for use as an antidepressant, anxiolytic, and sleep aid. DL-tryptophan also can be used as feed nutrition enhancer, antioxidants.

Definition

ChEBI: An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.

General Description

Tryptophan is the precursor for 5-hydroxy-tryptamin and an essential α-amino acid. DL-Tryptophan exists as a zwitterion during crystallization.

Biochem/physiol Actions

DL-Tryptophan binding to bovine serum albumin is employed for its affinity based chromatographic purification. Supplementation of tryptophan in diets of rat induce bladder tumor.

Safety Profile

Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx.