3-Bromo-4-hydroxypyridine
- Product Name
- 3-Bromo-4-hydroxypyridine
- CAS No.
- 36953-41-0
- Chemical Name
- 3-Bromo-4-hydroxypyridine
- Synonyms
- 3-Bromopyridin-4-ol;3-BROMO-4-PYRIDINOL;4-Pyridinol, 3-bromo-;3-bromo-1H-pyridin-4-one;4-HYDROXY-3-BROMOPYRIDINE;3-BROMO-4-HYDROXYPYRIDINE;3-BROMO-4-HYDROXYPYRIDINE 97%;3-Bromo-4-hydroxypyridine,97%;Synthesis of 3-bromopyridin-4-ol;3-Bromo-4-hydroxypyridine ISO 9001：2015 REACH
- CBNumber
- CB6110145
- Molecular Formula
- C5H4BrNO
- Formula Weight
- 174
- MOL File
- 36953-41-0.mol
3-Bromo-4-hydroxypyridine Property
- Melting point:
- 225-230℃
- Boiling point:
- 338.2±22.0 °C(Predicted)
- Density
- 1.788±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder
- pka
- 3.71±0.18(Predicted)
- color
- light yellow
- CAS DataBase Reference
- 36953-41-0(CAS DataBase Reference)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H33754
- Product name
- 3-Bromo-4-hydroxypyridine, 97%
- Packaging
- 1g
- Price
- $208.65
- Updated
- 2024/03/01
- Product number
- H33754
- Product name
- 3-Bromo-4-hydroxypyridine, 97%
- Packaging
- 5g
- Price
- $692.65
- Updated
- 2024/03/01
- Product number
- H33754
- Product name
- 3-Bromo-4-hydroxypyridine, 97%
- Packaging
- 250mg
- Price
- $75.6
- Updated
- 2021/12/16
- Product number
- B698850
- Product name
- 3-Bromopyridin-4-ol
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB140263
- Product name
- 3-Bromopyridin-4-ol
- Packaging
- 2g
- Price
- $74
- Updated
- 2021/12/16
3-Bromo-4-hydroxypyridine Chemical Properties,Usage,Production
Uses
3-Bromo-4-hydroxypyridine is a pyrrole that can be used in cancer treatment. It inhibits the growth of cancer cells by binding to MKN-45 on the cell surface, thereby preventing it from binding to other proteins and triggering cell proliferation.
Synthesis
3-Bromo-4-hydroxypyridine is synthesized from 3-bromo-5 hydroxypyridine by reacting it with ammonia or methylamine.
Concentrated sulfuric acid (85.0mL) and the 3-bromo-4-aminopyridine (113.0g, 0.65mol) were added successively to the distilled water (550.0mL) at 0°C, and then NaNO2 (63.1g, 0.91mol) aqueous solution (130.0mL) was added drop-wise to maintain the temperature between 0 and 5°C. After stirring at r. t. for 1h, the reaction mixture was heated at 95°C for a further 0.5h. Upon cooling to below 0°C, the mixture was alkalized to pH 6 with saturated sodium hydroxide solution, washed with ethyl acetate (200mL×3) and brine (200mL), dried over anhydrous Na2SO4, filtered and concentrated to yield 3-Bromo-4-hydroxypyridine as a yellow solid (75.1g, 66.2percent).
3-Bromo-4-hydroxypyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-4-hydroxypyridine Suppliers
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 3-Bromo-4-hydroxypyridine manufacturers
- Product
- 3-Bromo-4-hydroxypyridine 36953-41-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-24
- Product
- 3-Bromo-4-hydroxypyridine 36953-41-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 3-Bromo-4-hydroxypyridine 36953-41-0
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-04