ChemicalBook > CAS DataBase List > Triptorelin acetate

Triptorelin acetate

Product Name
Triptorelin acetate
CAS No.
140194-24-7
Chemical Name
Triptorelin acetate
Synonyms
TRIPTORELIN ACETATE;OvuGel;LHRH-A3;AY 25650;Wy 42422;Wy 42462;BIM 21003;BIM 21003C;Decapeptyl-Depot;Triptelin Acetate
CBNumber
CB61106806
Molecular Formula
C64H82N18O13.C2H4O2
Formula Weight
1371.52
MOL File
140194-24-7.mol
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Triptorelin acetate Property

solubility 
Aqueous Base (Slightly), Methanol (Very Slightly, Heated, Sonicated), Water (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
HPPONSCISKROOD-UXTGTKPXNA-N
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

TRC
Product number
T815800
Product name
TriptorelinAcetate
Packaging
500mg
Price
$845
Updated
2021/12/16
TRC
Product number
T815800
Product name
TriptorelinAcetate
Packaging
1g
Price
$1205
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
67415
Product name
TriptorelinAcetate
Packaging
50mg
Price
$2400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007777
Product name
TRIPTORELIN ACETATE
Purity
95.00%
Packaging
1G
Price
$2627.63
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007777
Product name
TRIPTORELIN ACETATE
Purity
95.00%
Packaging
5MG
Price
$608
Updated
2021/12/16
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Triptorelin acetate Chemical Properties,Usage,Production

Description

Triptorelin acetate (TA) is a GnRH agonist that was earlier used as a veterinary drug for a single fixed-time artificial insemination through the synchronised estrous cycle of weaned sows. The risk assessment was that the Food Safety Commission of Japan (FSCJ) concluded that TA is not likely to cause adverse effects on human health through dietary exposure. Because TA does not have genotoxicity relevant to human health and is degraded in the digestive tract, its oral bioavailability is low. TA is currently used for the treatment of central precocious puberty and assisted reproduction. Injectable TA alone or in combination with levonorgestrel intrauterine device is also used to treat endometrial atypical hyperplasia (EAH) . Combination therapy is more effective, improving patients' menstrual abnormalities, endometrial thickening and quality of life, and is safe.

Chemical Properties

White Solid

Uses

Synthetic peptide agonist analog of LH-RH. Triptoreline is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility.

Uses

Synthetic peptide agonist analog of LH-RH. Triptorelin acetate is a potent agonist of LH-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Antineoplastic (hormonal). Used in the treatment of endometriosis and infertility.

Side effects

Triptorelin acetate has been reported to have a possible side effect of severe bone loss. The first report was of an 8-year-old girl with central precocious puberty who experienced anaphylactic shock after the first injection of decapeptide containing triptorelin acetate (D,L lactide coglycolide), dextran 70, and polysorbate 80. However, it is also possible that it was a reaction to the polysorbate. Therefore, doctors should be aware of immediate reactions to drugs containing polysorbates.

Triptorelin acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Triptorelin acetate Suppliers

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View Lastest Price from Triptorelin acetate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Triptorelin acetate 140194-24-7
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2023-01-12
Strong peptide cross-border e-commerce Co. LTD
Product
Triptorelin acetate 140194-24-7
Price
US $5.00/kg
Min. Order
1kg
Purity
99+
Supply Ability
200t
Release date
2024-05-22
Strong peptide cross-border e-commerce Co. LTD
Product
Triptorelin acetate 140194-24-7
Price
US $5.00/kg
Min. Order
1kg
Purity
99+
Supply Ability
200t
Release date
2024-05-22

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