ChemicalBook > CAS DataBase List > 5-Bromo-2-chloropyridine

5-Bromo-2-chloropyridine

Product Name
5-Bromo-2-chloropyridine
CAS No.
53939-30-3
Chemical Name
5-Bromo-2-chloropyridine
Synonyms
N-methyl-1-(pyridin-3-yl)methanamine;CL025;2-CHLORO-5-BROMOPYRIDINE;5-BROMO-2-CHLOROPYRIDINE;3-Bromo-6-chloropyridine;2-cholro-5-broMopyridine;5-Bromo-2-chloro pyridne;5-bromo-2-chlorolpyridine;PYRIDINE, 5-BROMO-2-CHLORO-;2-chloro -5-pyridyl broMide
CBNumber
CB6177511
Molecular Formula
C5H3BrClN
Formula Weight
192.44
MOL File
53939-30-3.mol
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5-Bromo-2-chloropyridine Property

Melting point:
65-69 °C (lit.)
Boiling point:
208.1±20.0 °C(Predicted)
Density 
1.7783 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-2.25±0.10(Predicted)
form 
Crystalline Powder or Crystals
color 
Off-white
BRN 
108887
InChI
InChI=1S/C5H3BrClN/c6-4-1-2-5(7)8-3-4/h1-3H
InChIKey
PEAOEIWYQVXZMB-UHFFFAOYSA-N
SMILES
C1(Cl)=NC=C(Br)C=C1
CAS DataBase Reference
53939-30-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, IRRITANT-HARMFUL
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
551902
Product name
5-Bromo-2-chloropyridine
Purity
95%
Packaging
25g
Price
$125
Updated
2024/03/01
Sigma-Aldrich
Product number
551902
Product name
5-Bromo-2-chloropyridine
Purity
95%
Packaging
5g
Price
$55.7
Updated
2023/06/20
TCI Chemical
Product number
B2329
Product name
5-Bromo-2-chloropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$24
Updated
2024/03/01
TCI Chemical
Product number
B2329
Product name
5-Bromo-2-chloropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$94
Updated
2024/03/01
Alfa Aesar
Product number
B24862
Product name
5-Bromo-2-chloropyridine, 98%
Packaging
5g
Price
$31.65
Updated
2024/03/01
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5-Bromo-2-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

5-Bromo-2-chloropyridine may be used in the preparation of following compounds:

  • Amino-2-chloropyridine via palladium-catalyzed amination.
  • 5-Bromo-2-fluoropyridine via halogen-exchange reaction using anhydrous potassium fluoride.
  • 2-Chloro-5-(2,5-dimethoxyphenyl)pyridine via Suzuki coupling with 2,5-dimethoxyphenylboronic acid.

Synthesis

6-Chloro-pyridin-3-ylamine was dissolved slowly with constant stirring in 48% HBr solution (50 mL) at r.t. and then the solution was cooled to -10 °C. A solution of sodium nitrite in cold water was added dropwise at -10 °C with constant stirring over 2 h, followed by a solution of copper (I) bromide in 48% HBr dropwise. The mixture was then stirred at r.t. until complete. The mixture was neutralized with sodium carbonate and extracted with ethyl acetate. The organic phase was washed with brine, dried over sodium sulfate, and concentrated. The residue was purified by column chromatography on silica gel (60-120 mesh) eluting with 1% ethyl acetate/petroleum ether to afford 5- bromo-2-chloropyridine.

5-Bromo-2-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloropyridine-5-boronic acid
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5-Bromo-2-chloropyridine Suppliers

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View Lastest Price from 5-Bromo-2-chloropyridine manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-Chloro-5-bromopyridine 53939-30-3
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-05
Henan Fengda Chemical Co., Ltd
Product
2-Chloro-5-bromopyridine 53939-30-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Hebei Mujin Biotechnology Co.,Ltd
Product
2-Chloro-5-bromopyridine 53939-30-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-08

53939-30-3, 5-Bromo-2-chloropyridineRelated Search:

1-Hexadecylpyridinium bromide 2-Chloro-5-chloromethylpyridine Clopidol 2-Chloro-5-fluoropyridine 2-Chloro-3-cyanopyridine 5-Amino-2-chloropyridine 2-chloro-5-cyanopyridine 3-Bromo-6-chloro-2-methylpyridine 6-Chloro-2-methyl-3-nitropyridine 2-Chloro-5-hydroxypyridine 2-CHLORO-5-METHOXYPYRIDINE 2-Chloro-5-nitropyridine 2-Chloro-5-iodopyridine 5-Bromo-2-chlorobenzoic acid pyridinium Chlorochromate Difluorochloromethane Bromine 2-Chloropyridine

  • 5-BROMO-2-CHLOROPYRIDINE
  • 2-CHLORO-5-BROMOPYRIDINE
  • PYRIDINE, 5-BROMO-2-CHLORO-
  • 3-Bromo-6-chloropyridine
  • 5-bromo-2-chlorolpyridine
  • 5-Bromo-2-chloropyridine, 98+%
  • 5-BROMO-2-CHLOROPYRIDINE 98%
  • 2-CHLORO-5-BROMOPYRIDINE 5-BROMO-2-CHLORO-PYRIDINE
  • 5-Bromo-2-chloropyridine 2-Chloro-5-Bromopyridine
  • N-methyl-1-(pyridin-3-yl)methanamine
  • 2-cholro-5-broMopyridine
  • 2-chlorine-5- broMine Pyridine
  • 2-chloro -5-pyridyl broMide
  • 5-broMo -2-chlorine pyridine
  • CL025
  • 2-CHLORO-5-BROMOPYRIDINE 5-BROMO-2-CHLORO-PYR
  • 5-BroMo-2-chloropyridine, 97+%
  • 5-Bromo-2-chloro pyridne
  • 5-Bromo-2-chloropyridine &gt
  • 5-Bromo-2-chloropyridine ISO 9001：2015 REACH
  • 53939-30-3
  • 53930-30-3
  • 52939-30-3
  • C5H3BrClN
  • Pyridines
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Building Blocks
  • Chloropyridines
  • Halopyridines
  • Bromopyridines
  • Pyridines derivates
  • Halogenated
  • Organohalides
  • Bromopyridines
  • Chloropyridines
  • Halopyridines
  • Boronic Acid
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Variety of halogenated heterocyclic series
  • blocks
  • Bromides
  • Pyridines
  • Pyridine
  • pyridine derivative
  • Pyridine Series
  • Pyridines, Pyrimidines, Purines and Pteredines
  • compounds of pyridine
  • Risdiplam
  • bc0001