2-Amino-4,5-dichloropyridine

Product Name: 2-Amino-4,5-dichloropyridine
CAS No.: 188577-68-6
Chemical Name: 2-Amino-4,5-dichloropyridine
Synonyms: 4,5-Dichloro-2-pyridinamine;4,5-dichloropyridin-2-amine;2-AMINO-4,5-DICHLOROPYRIDINE;2-Pyridinamine, 4,5-dichloro-;4,5-Dichloro-pyridin-2-ylamine;2-AMINO-4,5-DICHLOROPYRIDINE 97%;2-Pyridinamine,4,5-dichloro-(9CI);REF DUPL: 2-amino-4,5-dichloropyridine;188577-68-6;2-Amino-4,5-dichloropyridine ISO 9001：2015 REACH
CBNumber: CB6184700
Molecular Formula: C5H4Cl2N2
Formula Weight: 163
MOL File: 188577-68-6.mol

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2-Amino-4,5-dichloropyridine Property

Boiling point:: 269.8±35.0 °C(Predicted)
Density: 1.497±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.63±0.24(Predicted)
form: powder
color: Red brown
InChI: InChI=1S/C5H4Cl2N2/c6-3-1-5(8)9-2-4(3)7/h1-2H,(H2,8,9)
InChIKey: CRRAQLWJVYODCL-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(Cl)C(Cl)=C1

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Safety

Hazard Codes: T
RIDADR: UN2811
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHB00293
Product name: 2-Amino-4,5-dichloropyridine
Purity: AldrichCPR
Packaging: 1 g
Price: $107
Updated: 2025/07/31

TRC

Product number: A596900
Product name: 2-Amino-4,5-dichloropyridine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A596900
Product name: 2-Amino-4,5-dichloropyridine
Packaging: 500mg
Price: $115
Updated: 2021/12/16

Apolloscientific

Product number: OR59818
Product name: 2-Amino-4,5-dichloropyridine
Packaging: 250mg
Price: $27
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-Z6
Product name: 2-Amino-4,5-dichloropyridine
Packaging: 250mg
Price: $29
Updated: 2021/12/16

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2-Amino-4,5-dichloropyridine Chemical Properties,Usage,Production

Synthesis

19798-80-2

188577-68-6

General procedure for the synthesis of 4,5-dichloropyridin-2-amine from 2-amino-4-chloropyridine: N-chlorosuccinimide (NCS, 2.67 g, 20.0 mmol) was added to a solution of 2-amino-4-chloropyridine (1.28 g, 10.0 mmol) in DMF (40 mL) at -20 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 24 hours. Upon completion of the reaction, the mixture was poured into ice water (300 mL) and extracted with ethyl acetate. The combined organic phases were washed sequentially with 1 M sodium hydroxide solution and saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography to afford the target compound 4,5-dichloropyridin-2-amine (1.12 g, 69.0% yield).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 1, p. 60 - 67
[2] European Journal of Medicinal Chemistry, 2016, vol. 117, p. 19 - 32
[3] Patent: WO2016/124553, 2016, A1. Location in patent: Page/Page column 71-72
[4] Patent: WO2018/11138, 2018, A1. Location in patent: Page/Page column 69-70
[5] Synthetic Communications, 1997, vol. 27, # 5, p. 861 - 870

2-Amino-4,5-dichloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-4,5-dichloropyridine Suppliers

China 115 Europe 1 Germany 1 India 3 Sweden 1 United Kingdom 2 United States 13 Global 136

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China Langchem Inc.

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View Lastest Price from 2-Amino-4,5-dichloropyridine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Amino-4,5-dichloropyridine 188577-68-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-06

Career Henan Chemical Co

Product: 2-Amino-4,5-dichloropyridine 188577-68-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-31

188577-68-6, 2-Amino-4,5-dichloropyridineRelated Search:

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2-AMINO-4,5-DICHLOROPYRIDINE

4,5-dichloropyridin-2-amine

2-Pyridinamine,4,5-dichloro-(9CI)

2-AMINO-4,5-DICHLOROPYRIDINE 97%

REF DUPL: 2-amino-4,5-dichloropyridine

2-Pyridinamine, 4,5-dichloro-

4,5-Dichloro-pyridin-2-ylamine

4,5-Dichloro-2-pyridinamine

2-Amino-4,5-dichloropyridine ISO 9001：2015 REACH

188577-68-6

Pyridines

HALIDE