ChemicalBook > CAS DataBase List > 3-Chloroisonicotinic acid

3-Chloroisonicotinic acid

Product Name: 3-Chloroisonicotinic acid
CAS No.: 88912-27-0
Chemical Name: 3-Chloroisonicotinic acid
Synonyms: 3-CHLOROISONICOTINIC ACID;3- chlorineisonicotinic acid;3-Chloroisonicotinic Acid >3-Chloro-4-pyridine carboxlic acid;3-CHLORO-4-PYRIDINECARBOXYLIC ACID;3-CHLOROPYRIDINE-4-CARBOXYLIC ACID;3-Chloropyridin-4-ylcarboxylic acid;4-Pyridinecarboxylic acid, 3-chloro-;3-Chloropyridine-4-carboxylic acid 97%;3-Chloropyridine-4-carboxylic Acid, 97+%
CBNumber: CB6249797
Molecular Formula: C6H4ClNO2
Formula Weight: 157.55
MOL File: 88912-27-0.mol

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3-Chloroisonicotinic acid Property

Melting point:: 227-231 °C (dec.)(lit.)
Boiling point:: 387.0±22.0 °C(Predicted)
Density: 1.470±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 0.12±0.25(Predicted)
form: Solution
color: Brown to dark green to black
InChIKey: MYAZXWFEMDJTFE-UHFFFAOYSA-N
CAS DataBase Reference: 88912-27-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 633410
Product name: 3-Chloropyridine-4-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $31.7
Updated: 2023/06/20

Sigma-Aldrich

Product number: 633410
Product name: 3-Chloropyridine-4-carboxylic acid
Purity: 97%
Packaging: 5g
Price: $38.4
Updated: 2023/06/20

TCI Chemical

Product number: C2983
Product name: 3-Chloroisonicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $78
Updated: 2025/07/31

TCI Chemical

Product number: C2983
Product name: 3-Chloroisonicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $308
Updated: 2025/07/31

TRC

Product number: C367378
Product name: 3-Chloroisonicotinic Acid
Packaging: 5g
Price: $75
Updated: 2021/12/16

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3-Chloroisonicotinic acid Chemical Properties,Usage,Production

Synthesis

626-60-8

88912-27-0

A. Synthesis of 3-chloro-N-(4-chlorophenyl)pyridine-4-carboxamide. At -78 °C, 3-chloropyridine (1.00 mL, 10.5 mmol) was dissolved in THF and a freshly prepared lithium diisopropylammonium THF solution [prepared by the reaction of butyl lithium (7.21 mL, 11.5 mmol) with diisopropylamine (11.5 mmol)] was slowly added. After 0.25 h of reaction, carbon dioxide gas was passed into the mixture and slowly warmed to room temperature. After completion of the reaction, the mixture was concentrated and subsequently partitioned between EtOAc and water. The aqueous layer was washed twice with EtOAc. The pH of the aqueous layer was adjusted to about 3 by adding 1N HCl and extracted three more times with EtOAc. The organic phases were combined, dried with magnesium sulfate and concentrated. The residue was recrystallized by EtOAc to give 200 mg (12% yield) of 3-chloroisonicotinic acid.

References

[1] Patent: US6610704, 2003, B1

3-Chloroisonicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Chloroisonicotinic acid manufacturers

Dideu Industries Group Limited

Product: 3-Chloroisonicotinic acid 88912-27-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-25

Career Henan Chemical Co

Product: 3-Chloroisonicotinic acid 88912-27-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-14

88912-27-0, 3-Chloroisonicotinic acidRelated Search:

4-Chlorophenyl isocyanate Chlorosulfonyl isocyanate Chlorobromoisocyanurate Ethyl 2-(Chlorosulfonyl)acetate Chloromethyl isopropyl carbonate Glycine Folic acid Isopropyl chloroformate Nicotinic acid Isobutyl chloroformate Isonicotinic acid Methyl isonicotinate 1-Chloro-2-methylpropane 2-Chloroisonicotinic acid ,97%,2-CHLORO-4-PYRIDINECARBOXYLIC ACID / 2-CHLOROISONICOTINIC ACID,2-CHLOROISONICOTINIC ACID 2,6-Dichloroisonicotinic acid 3,5-DICHLOROISONICOTINIC ACID 2-BROMO-3,5-DICHLOROISONICOTINIC ACID 2,5-Dichloroisonicotinic acid

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3-Chloroisonicotinic acid ISO 9001：2015 REACH

88912-27-0

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