ChemicalBook > CAS DataBase List > 1-Hydroxy-2-naphthoic acid

1-Hydroxy-2-naphthoic acid

Product Name
1-Hydroxy-2-naphthoic acid
CAS No.
86-48-6
Chemical Name
1-Hydroxy-2-naphthoic acid
Synonyms
NSC 3717;Xinafoic acid.;RARECHEM AL BE 0359;2-Carboxy-1-naphthol;1-Hydroxy-2-naphthoi;LABOTEST-BB LT00452757;1-Hydroxy-2-phthoic acid;hydroxy-2-naphthoic acid;1-Hydroxy-2-naphthoicaci;1-hydroxy-β-naphthoic acid
CBNumber
CB6317591
Molecular Formula
C11H8O3
Formula Weight
188.18
MOL File
86-48-6.mol
More
Less

1-Hydroxy-2-naphthoic acid Property

Melting point:
195-200 °C (dec.) (lit.)
Boiling point:
283.17°C (rough estimate)
Density 
1.2100 (rough estimate)
refractive index 
1.6310 (estimate)
Flash point:
150 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: freely soluble
form 
Powder or Crystals
pka
3.02±0.30(Predicted)
color 
White to slightly pink to tan
Water Solubility 
SOLUBLE IN HOT WATER
Merck 
14,4834
BRN 
974438
InChIKey
SJJCQDRGABAVBB-UHFFFAOYSA-N
LogP
3.196 (est)
CAS DataBase Reference
86-48-6(CAS DataBase Reference)
EPA Substance Registry System
1-Hydroxy-2-naphthoic acid (86-48-6)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-37
WGK Germany 
3
TSCA 
Yes
HS Code 
29182910
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
109630
Product name
1-Hydroxy-2-naphthoic acid
Purity
≥97.0%
Packaging
5g
Price
$34.1
Updated
2024/03/01
Sigma-Aldrich
Product number
109630
Product name
1-Hydroxy-2-naphthoic acid
Purity
≥97.0%
Packaging
100g
Price
$59.5
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$32
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$322
Updated
2024/03/01
TCI Chemical
Product number
H0279
Product name
1-Hydroxy-2-naphthoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
100g
Price
$97
Updated
2024/03/01
More
Less

1-Hydroxy-2-naphthoic acid Chemical Properties,Usage,Production

Chemical Properties

beige to brown-grey powder. 1-Hydroxy-2-naphthoic acid [86-48-6], C11H8O3, Mr 188.17, mp 200℃, is only sparingly soluble in hot water but readily soluble in alkali and ethanol. It couples with diazo compounds in the 4-position and, with excess, in the 4,7-positions. It is sulfonated by oleum to give the 4-sulfonic and then the 4,7-disulfonic acids. Halogenation occurs in the 4-position, and nitrosation gives 2-nitroso-1-naphthol.

Uses

Metabolite from phenanthrene degradation. 1-Hydroxy-2-naphthoic acid is used as an intermediate for azo and triphenylmethane dyes and, more recently, for color-film dyes.

Uses

It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Definition

ChEBI: 1-hydroxy-2-naphthoic acid is a naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms. It has a role as a bacterial xenobiotic metabolite and a fungal xenobiotic metabolite. It is a naphthoic acid, a member of naphthols and a hydroxy monocarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a 1-hydroxy-2-naphthoate.

Preparation

Treatment of the dried sodium salt of 1-naphthol with carbon dioxide at 135℃ under pressure gives an 80 % yield of product.

General Description

1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.

Purification Methods

Successively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]

1-Hydroxy-2-naphthoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-Hydroxy-2-naphthoic acid Suppliers

Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32159
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38630
Advantage
58
SynQuest Laboratories, Inc. (Part of Central Glass Co., Ltd.)
Tel
--
Fax
--
Email
nfo@synquestlabs.com
Country
United States
ProdList
1897
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)
Tel
--
Fax
--
Email
serv@mpbio.com
Country
United States
ProdList
1854
Advantage
58
SynQuest Laboratories, Inc.,
Tel
--
Fax
--
Country
United States
ProdList
2301
Advantage
58
MuseChem (A division of Adv Biolabs, Inc.)
Tel
--
Fax
--
Email
@musechem.com
Country
United States
ProdList
246
Advantage
58
2A Biotech USA
Tel
--
Fax
--
Email
info@2abiotech.com
Country
United States
ProdList
1785
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Exim-Indis, Inc. (part of Exim Corporation and Indis N.V.)
Tel
--
Fax
--
Email
info@exim-indis.com
Country
United States
ProdList
440
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
CALSAK CORPORATION
Tel
--
Fax
--
Email
calsak@calsak.com
Country
United States
ProdList
430
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
Ambeed, Inc.
Tel
--
Fax
--
Email
info@ambeed.com
Country
United States
ProdList
502
Advantage
58
TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)
Tel
--
Fax
--
Email
.Crew@tcichemicals.com
Country
United States
ProdList
3164
Advantage
58
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Spectrum Chemical Mfg. Corp.
Tel
--
Fax
--
Email
marketing@spectrumchemical.com
Country
United States
ProdList
3113
Advantage
60
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
AA Blocks LLC
Tel
--
Fax
--
Email
s@aablocks.com
Country
United States
ProdList
536
Advantage
58
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Bosgen Chemical Inc.
Tel
--
Fax
--
Email
sale@chemapi.com
Country
United States
ProdList
609
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Chemiplus Corporation
Tel
--
Fax
--
Email
okazaki@chemiplus.com
Country
United States
ProdList
3198
Advantage
38
BD Biosciences
Tel
--
Fax
--
Country
United States
ProdList
5013
Advantage
82
Fine Chem Trading LTD
Tel
--
Fax
--
Email
chemfinder@chemfinder.co.uk
Country
United States
ProdList
1609
Advantage
64
CALSAK CHEMICALS
Tel
--
Fax
--
Email
chemicals@calsak.com
Country
United States
ProdList
54
Advantage
42
Varian, Inc.
Tel
--
Fax
--
Email
custserv@varianinc.com
Country
United States
ProdList
224
Advantage
85
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
More
Less

View Lastest Price from 1-Hydroxy-2-naphthoic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Mujin Biotechnology Co.,Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-13
Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Hydroxy-2-naphthoic acid 86-48-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01

86-48-6, 1-Hydroxy-2-naphthoic acidRelated Search:


  • LABOTEST-BB LT00452757
  • RARECHEM AL BE 0359
  • Salmeterol Hydroxynaphthoic Acid Impurity (USP)
  • ALPHA-HYDROXYNAPHTHOIC ACID
  • 1-NAPHTHOL-2-CARBOXYLIC ACID
  • 1-HYDROXY-2-NAPHTHOIC ACID
  • 1-HYDROXY-NAPHTHALENE-2-CARBONIC ACID
  • 1-Hydroxy-2-phthoic acid
  • 1-Hydroxy-naphthalene-2-carboxylic acid for synthesis
  • Salmeterol Hydroxynaphthoic Acid Impurity
  • 1-hydroxy-β-naphthoic acid
  • 2-Naphthalenecarboxylic acid, 1-hydroxy-
  • 1-HYDROXYNAPHTHALENE-2-CARBOXYLIC ACID (1-HYDROXY-2-NAPHTHOIC ACID)
  • 1-Hydroxy-2-naphthoic acid, 98+%
  • 2-Carboxy-1-naphthol
  • Hydroxynaphthalene-2-carboxylic acid
  • Naphthol-2-carboxylic acid
  • 1-Hydroxy-2-naphthoic acid,99%
  • 1-Hydroxynaphthalene-2-carboxylic acid, 2-Carboxy-1-hydroxynaphthalene
  • 1-Hydroxy-2-naphthoic acid, 99% 100GR
  • 1-Hydroxy-2-naphthoic acid, 99% 5GR
  • NSC 3717
  • Xinafoic acid.
  • 1-Hydroxy-2-naphthoic acid >=97.0%
  • 1-hydroxy-2-naphthalenecarboxylicaci
  • 1-hydroxy-2-Naphthalenecarboxylicacid
  • hydroxy-2-naphthoic acid
  • 1-Hydroxy-2-naphthoic acid, 97%, for synthesis
  • 1-Hydroxy-2-naphthoicAcid&gt
  • 1-Hydroxy-2-naphthoicaci
  • 1-Hydroxy-2-naphthoic acid ISO 9001:2015 REACH
  • 1-Hydroxy-2-naphthoi
  • 1-Hydroxy-2-naphthoic acid, 10 mM in DMSO
  • 86-48-6
  • 84-48-6
  • HOC10H6COOH
  • C11H7O3
  • Organic Building Blocks
  • Building Blocks
  • Carboxylic Acids
  • Carbonyl Compounds
  • C11 to C12
  • CARBOXYLIC ACID
  • Aromatics
  • Intermediates of Dyes and Pigments
  • bc0001