Azadibenzocyclooctyne-Biotin conjugate

Product Name: Azadibenzocyclooctyne-Biotin conjugate
CAS No.: 1418217-95-4
Chemical Name: Azadibenzocyclooctyne-Biotin conjugate
Synonyms: DBCO-Biotin;DBCO-(CH2)2-NH2-BIOTIN;Azadibenzocyclooctyne-Biotin conjugate;DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate;(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-
CBNumber: CB63309380
Molecular Formula: C28H30N4O3S
Formula Weight: 502.63
MOL File: 1418217-95-4.mol

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Azadibenzocyclooctyne-Biotin conjugate Property

Boiling point:: 905.9±65.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: -20°C, protect from light, stored under nitrogen
form: Solid
pka: 13.90±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Iris Biotech GmbH

Product number: LS-4270
Product name: Biotin-DBCO
Packaging: 100mg
Price: $810
Updated: 2021/12/16

Iris Biotech GmbH

Product number: LS-4270
Product name: Biotin-DBCO
Packaging: 250mg
Price: $1620
Updated: 2021/12/16

purepeg

Product number: 288702
Product name: DBCO-Biotin
Purity: min.95%
Packaging: 100mg
Price: $650
Updated: 2021/12/16

DC Chemicals

Product number: DC21887
Product name: DBCO-Biotin
Purity: >98%
Packaging: 250mg
Price: $1700
Updated: 2021/12/16

DC Chemicals

Product number: DC21887
Product name: DBCO-Biotin
Purity: >98%
Packaging: 1g
Price: $3400
Updated: 2021/12/16

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Azadibenzocyclooctyne-Biotin conjugate Chemical Properties,Usage,Production

Uses

DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azadibenzocyclooctyne-Biotin conjugate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azadibenzocyclooctyne-Biotin conjugate manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: DBCO-Biotin 1418217-95-4
Price: US $0.00/mg
Min. Order: 25mg
Purity: >99.00%
Supply Ability: 100
Release date: 2024-03-20

1418217-95-4, Azadibenzocyclooctyne-Biotin conjugateRelated Search:

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DBCO-Biotin

DBCO-Biotin,Azadibenzocyclooctyne-Biotin conjugate

Azadibenzocyclooctyne-Biotin conjugate

DBCO-(CH2)2-NH2-BIOTIN

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-, (3aS,4S,6aR)-

(3AS,4S,6aR)-N-[3-(11,12-Didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide

1418217-95-4