AC-LEHD-AFC

Product Name: AC-LEHD-AFC
CAS No.: 210345-03-2
Chemical Name: AC-LEHD-AFC
Synonyms: AC-LEHD-AFC;Ac-LEHD-AFC TFA salt;AC-LEU-GLU-HIS-ASP-AFC;CASPASE-9 SUBSTRATE I, FLUOROGENIC;CASPASE 9 SUBSTRATE 1F, FLUOROGENIC;AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)
CBNumber: CB6377625
Molecular Formula: C33H38F3N7O11
Formula Weight: 765.69
MOL File: 210345-03-2.mol

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AC-LEHD-AFC Property

Boiling point:: 1211.9±65.0 °C(Predicted)
Density: 1.457±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO/DMF: 20 mM
form: powder
pka: 4.07±0.10(Predicted)
color: white
Water Solubility: Soluble to 1 mg/ml in water

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 218765
Product name: Caspase-9 Substrate I, Fluorogenic
Purity: A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6).
Packaging: 1MG
Price: $155
Updated: 2024/03/01

Sigma-Aldrich

Product number: 218765
Product name: Caspase-9 Substrate I, Fluorogenic
Purity: A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6).
Packaging: 5MG
Price: $425
Updated: 2024/03/01

Cayman Chemical

Product number: 17051
Product name: Ac-LEHD-AFC
Purity: ≥95%
Packaging: 1mg
Price: $40
Updated: 2021/12/16

Cayman Chemical

Product number: 17051
Product name: Ac-LEHD-AFC
Purity: ≥95%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

Cayman Chemical

Product number: 17051
Product name: Ac-LEHD-AFC
Purity: ≥95%
Packaging: 10mg
Price: $220
Updated: 2021/12/16

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AC-LEHD-AFC Chemical Properties,Usage,Production

Uses

Ac-LEHD-AFC Trifluoroacetic Acid Salt is a fluorogenic substrate that is cleaved by caspases (4,5 and 9). This activity is quantified by fluorescent detection of free AFC. Caspase-9 activation is critical for intrinsic cell death.

Biological Activity

Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.

AC-LEHD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-LEHD-AFC Suppliers

China 61 Germany 1 Japan 1 Switzerland 2 United Kingdom 2 United States 14 Global 81

Tocris Bioscience

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Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
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VWR International

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Email: solutions@vwr.com
Country: United Kingdom
ProdList: 6548
Advantage: 82

210345-03-2, AC-LEHD-AFCRelated Search:

Z-PHE-DL-ALA-FLUOROMETHYLKETONE AC-YVAD-PNA CASPASE INHIBITOR3 AC-VEID-AMC Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE Z-YVAD-AFC ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL AC-VDVAD-CHO AC-DEVD-AFC PAC1 AC-DEVD-CHO AC-LEU-GLU-THR-ASP-AFC AC-VDVAD-PNA Z-VAD-FMK AC-LEU-GLU-HIS-ASP-AMC AC-LEHD-AFC

N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN

N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)

N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC

AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN

AC-LEU-GLU-HIS-ASP-AFC

AC-LEHD-AFC

CASPASE-9 SUBSTRATE I, FLUOROGENIC

CASPASE 9 SUBSTRATE 1F, FLUOROGENIC

L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- (9CI)

4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

Ac-LEHD-AFC TFA salt

210345-03-2

C33H38F3N7O11

C33H38O11N7F3

Caspases/Apoptosis

peptide