ChemicalBook > CAS DataBase List > 5-AMINOINDAZOLE

5-AMINOINDAZOLE

Product Name
5-AMINOINDAZOLE
CAS No.
19335-11-6
Chemical Name
5-AMINOINDAZOLE
Synonyms
1H-INDAZOL-5-AMINE;5-indazolamine;5-AMINOINDAZOLE;indazol-5-ylamine;5-amino-1h-indazol;5-Aminoindazole,97%;5-Aminoindazole,99%;5-Aminoindazole 98%;IFLAB-BB F2108-0020;TIMTEC-BB SBB006576
CBNumber
CB6406222
Molecular Formula
C7H7N3
Formula Weight
133.15
MOL File
19335-11-6.mol
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5-AMINOINDAZOLE Property

Melting point:
175-178 °C (lit.)
Boiling point:
235.67°C (rough estimate)
Density 
1.1873 (rough estimate)
refractive index 
1.5341 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
14.52±0.40(Predicted)
color 
White to Brown
BRN 
3259
InChI
InChI=1S/C7H7N3/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,8H2,(H,9,10)
InChIKey
XBTOSRUBOXQWBO-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(N)C=C2)C=N1
CAS DataBase Reference
19335-11-6(CAS DataBase Reference)
EPA Substance Registry System
5-Aminoindazole (19335-11-6)
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Safety

Hazard Codes 
T,Xn
Risk Statements 
25-36/37/38
Safety Statements 
26-36-45-37/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
NK7711000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A59557
Product name
5-Aminoindazole
Purity
97%
Packaging
5g
Price
$51.25
Updated
2025/07/31
Sigma-Aldrich
Product number
A59557
Product name
5-Aminoindazole
Purity
97%
Packaging
25g
Price
$262
Updated
2023/06/20
TCI Chemical
Product number
A0797
Product name
5-Aminoindazole
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$66
Updated
2025/07/31
TCI Chemical
Product number
A0797
Product name
5-Aminoindazole
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$237
Updated
2025/07/31
SynQuest Laboratories
Product number
3H30-1-9V
Product name
5-Amino-1H-indazole
Purity
97%
Packaging
1g
Price
$10
Updated
2021/12/16
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5-AMINOINDAZOLE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

5-Amino-1H-indazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Application

1H-Indazol-5-amine is a useful research chemical, an indazole derivatives with anti- inflammatory properties.

Synthesis

5401-94-5

19335-11-6

General procedure for the synthesis of 5-aminoindazole from 5-nitroindazole: To a 5000 mL autoclave equipped with a hydrogen inlet, thermometer, and mechanical stirrer, a tetrahydrofuran solution (THF, 3500 mL) of 5-nitro-1H-indazole (500 g, 3.06 mol) was added. Palladium-carbon catalyst (10%, 50 g, 141 mmol) was subsequently added. The reaction mixture was stirred overnight at 25 °C under hydrogen atmosphere (5 kg pressure). Upon completion of the reaction, the system was purged with nitrogen and the mixture was subsequently filtered. The filtrate was concentrated under vacuum to give 5-aminoindazole as a brown solid (420 g, 100% yield). Mass spectrometry (MS) data: m/z 134.1 ([M+H]+).

References

[1] Patent: US2012/28984, 2012, A1. Location in patent: Page/Page column 3
[2] Patent: WO2006/71940, 2006, A2. Location in patent: Page/Page column 409
[3] Patent: US2008/90856, 2008, A1. Location in patent: Page/Page column 45
[4] Patent: WO2013/36232, 2013, A2. Location in patent: Paragraph 00321
[5] MedChemComm, 2016, vol. 7, # 5, p. 881 - 899

5-AMINOINDAZOLE Preparation Products And Raw materials

Raw materials

Palladium Sodium nitrite 2-Methyl-4-nitroaniline Acetic acid

Preparation Products

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View Lastest Price from 5-AMINOINDAZOLE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
5-AMINOINDAZOLE 19335-11-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
R&D Scientific Inc.
Product
5-Amino-1H-indazole 19335-11-6
Price
US $1180.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-07-25
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-AMINOINDAZOLE 19335-11-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

19335-11-6, 5-AMINOINDAZOLERelated Search:

5-Nitroindazole 2-METHYL-5-NITRO-2H-INDAZOLE Piroxantrone 1-METHYL-5-NITRO-1H-INDAZOLE 3-Amino-5-nitroindazole 3-CHLORO-5-NITRO-1H-INDAZOLE 5-AMINOINDAZOLE Losoxantrone 5-AMINO-3-BROMO (1H)INDAZOLE 4-Aminoindazole 5-BOC-AMINOINDAZOLE 6-AMINO-3-CHLORO (1H)INDAZOLE 6-AMINO-3-BROMO (1H)INDAZOLE Aminoindazole,6-AMINOINDAZOLE 3-AMINOINDAZOLE 5-AMINOINDAZOLE-3-CARBOXYLIC ACID 3-methyl-1H-indazol-6-amine 1H-INDAZOL-7-AMINE

  • indazol-5-ylamine
  • 5-indazolamine
  • 5-Aminoindazole 98%
  • 5-Aminoindazole,99%
  • 5-Aminoindazole,97%
  • 5-Amino-1H-indazole,98%
  • 5-Aminoindazole≥ 98% (TLC)
  • 1H-Indazole, 5-amino-
  • 5-amino-1h-indazol
  • TIMTEC-BB SBB006576
  • IFLAB-BB F2108-0020
  • LABOTEST-BB LT00080768
  • 5-AMINOINDAZOLE
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  • 1H-INDAZOL-5-AMINE
  • 1H-INDAZOLE-5-AMINE
  • 5-Aminoindazole &gt
  • 5-Aminoindazole-98%
  • 1H-Indazol-5-amine (9CI, ACI)
  • 5-Aminoindazole (ambeed)
  • Axitinib Impurity 55
  • 19335-11-6
  • Indazoles
  • Heterocyclic Building Blocks
  • Building Blocks
  • pharmacetical
  • Indazole
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  • Indazoles
  • Amines and Anilines
  • Heterocycles
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