ChemicalBook > CAS DataBase List > MMP-9 INHIBITOR I
MMP-9 INHIBITOR I
- Product Name
- MMP-9 INHIBITOR I
- CAS No.
- 1177749-58-4
- Chemical Name
- MMP-9 INHIBITOR I
- Synonyms
- MMP-9 Inhibitor;MMP-9 INHIBITOR I;MMP-9 Inhibitor II;MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem;Benzamide, 5-[(diethylamino)methyl]-N-hydroxy-2-[[(4-methoxyphenoxy)sulfinyl](phenylmethyl)amino]-3-methyl-
- CBNumber
- CB6666273
- Molecular Formula
- C27H33N3O5S
- Formula Weight
- 511.63
- MOL File
- 1177749-58-4.mol
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MMP-9 INHIBITOR I Property
- Density
- 1.276±0.06 g/cm3(Predicted)
- storage temp.
- -20C
- form
- Off-white solid
- pka
- 8.28±0.42(Predicted)
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MMP-9 INHIBITOR I Chemical Properties,Usage,Production
Definition
ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether.
General Description
A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 μM) and MMP-13 IC50 = 113 nM) at higher concentrations.
Biochem/physiol Actions
Primary TargetMMP-9
MMP-9 INHIBITOR I Preparation Products And Raw materials
Raw materials
Preparation Products
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1177749-58-4, MMP-9 INHIBITOR IRelated Search:
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