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MMP-9 INHIBITOR I

Product Name
MMP-9 INHIBITOR I
CAS No.
1177749-58-4
Chemical Name
MMP-9 INHIBITOR I
Synonyms
MMP-9 Inhibitor;MMP-9 INHIBITOR I;MMP-9 Inhibitor II;MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem;Benzamide, 5-[(diethylamino)methyl]-N-hydroxy-2-[[(4-methoxyphenoxy)sulfinyl](phenylmethyl)amino]-3-methyl-
CBNumber
CB6666273
Molecular Formula
C27H33N3O5S
Formula Weight
511.63
MOL File
1177749-58-4.mol
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MMP-9 INHIBITOR I Property

Density 
1.276±0.06 g/cm3(Predicted)
storage temp. 
-20C
form 
Off-white solid
pka
8.28±0.42(Predicted)
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Hazard and Precautionary Statements (GHS)

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MMP-9 INHIBITOR I Chemical Properties,Usage,Production

Definition

ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether.

General Description

A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 μM) and MMP-13 IC50 = 113 nM) at higher concentrations.

Biochem/physiol Actions

Primary TargetMMP-9

MMP-9 INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

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MMP-9 INHIBITOR I Suppliers

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