ChemicalBook > CAS DataBase List > HISPIDULIN

HISPIDULIN

Product Name
HISPIDULIN
CAS No.
1447-88-7
Chemical Name
HISPIDULIN
Synonyms
Dinatin;HISPIDULIN;Hispedulin;Hispidulin-RM;Methoxyapigenin;Hispidulin, >99%;6-Methoxyapigenin;Hispidulin(Dinatin);6-Methylscutellarein;SCUTELLAREIN 6-METHYL ETHER
CBNumber
CB6723941
Molecular Formula
C16H12O6
Formula Weight
300.26
MOL File
1447-88-7.mol
More
Less

HISPIDULIN Property

Melting point:
291-292 °C
Boiling point:
601.5±55.0 °C(Predicted)
Density 
1.512±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble20mg/mL, clear
form 
powder
pka
6.51±0.40(Predicted)
color 
white to beige
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
DJ2996000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0582
Product name
Hispidulin
Purity
≥98% (HPLC)
Packaging
5mg
Price
$140
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0582
Product name
Hispidulin
Purity
≥98% (HPLC)
Packaging
25mg
Price
$543
Updated
2024/03/01
Cayman Chemical
Product number
26383
Product name
Hispidulin
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
26383
Product name
Hispidulin
Packaging
25mg
Price
$305
Updated
2024/03/01
Cayman Chemical
Product number
26383
Product name
Hispidulin
Packaging
1mg
Price
$32
Updated
2024/03/01
More
Less

HISPIDULIN Chemical Properties,Usage,Production

Uses

Hispidulin has been used as a calibration standard:

  • in high-performance liquid chromatography (HPLC) for quantification of Clerodendrum petasites flavonoids
  • in liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS) analysis
  • in reverse-phase high-performance liquid chromatography with a diode-array detector (HPLC-DAD) and high-performance thin-layer chromatography (HPTLC)

Definition

ChEBI: A monomethoxyflavone that is scutellarein methylated at position 6.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biological Activity

Partial positive allosteric modulator at the benzodiazepine receptor (IC 50 = 1.3 μ M for inhibition of flumazenil binding); natural sage flavone. Stimulates GABA-induced chloride currents in Xenopus oocytes expressing α 1 α 2-, α 3-, α 5- or α 6- β 2 γ 2S GABA A receptors. Brain penetrant; oral administration reduces seizures in a gerbil model of epilepsy. Also has antifungal, antiproliferative, antioxidant and antithrombotic properties.

Biochem/physiol Actions

Hispidulin is a bioactive flavonoid with a variety of effects including antiproliferative, antifungal, anti-inflammatory, antioxidative and antiepileptic activity. Like EGCG, hispidulin appears to activate AMPK and inhibit the PI3K/Akt/mTOR pathway. The antiepileptic activity may be due to additional activity as a benzodiazepine (BZD) receptor ligand.

HISPIDULIN Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

HISPIDULIN Suppliers

Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-400-186-5138 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1007
Advantage
58
More
Less

View Lastest Price from HISPIDULIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Hispidulin 1447-88-7
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
100 g
Release date
2020-08-13
Career Henan Chemical Co
Product
HISPIDULIN 1447-88-7
Price
US $6.60/KG
Min. Order
500g
Purity
98%
Supply Ability
1kg, 50kg, 100kg
Release date
2019-12-25

1447-88-7, HISPIDULINRelated Search:


  • SCUTELLAREIN 6-METHYL ETHER
  • 4',5,7-Trihydroxy-6-methoxyflavone
  • 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
  • 6-Methoxyapigenin
  • 6-Methylscutellarein
  • Hispidulin(Dinatin)
  • Methoxyapigenin
  • Dinatin
  • Hispedulin
  • HISPIDULIN
  • Hispidulin, >99%
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
  • 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
  • Hispidulin-RM
  • 1447-88-7
  • Miscellaneous Natural Products