Etofenamate

Product Name: Etofenamate
CAS No.: 30544-47-9
Chemical Name: Etofenamate
Synonyms: ReuMon;TV-485;Rheumon;TVX-485;CS-1431;Bayrogel;Etofenate;Etofenamate;TrauMon Gel;Ethofenamate
CBNumber: CB6883241
Molecular Formula: C18H18F3NO4
Formula Weight: 369.33
MOL File: 30544-47-9.mol

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Etofenamate Property

Melting point:: 25°C
Boiling point:: bp.001 130-135°
Density: 1.2866 (estimate)
refractive index: nD25 1.564
storage temp.: Sealed in dry,2-8°C
solubility: Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
pka: 14.32±0.10(Predicted)
form: Oil
color: Light yellow to yellow
Stability:: Light Sensitive
InChI: InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2
InChIKey: XILVEPYQJIOVNB-UHFFFAOYSA-N
SMILES: C(OCCOCCO)(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1

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Safety

RIDADR: UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
Toxicity: LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E2499901
Product name: Etofenamate for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 20 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: E2499900
Product name: Etofenamate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 50 mg
Price: $153
Updated: 2025/07/31

Sigma-Aldrich

Product number: E2499901
Product name: Etofenamate for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: e2499901
Price: $153
Updated: 2024/03/01

Sigma-Aldrich

Product number: E2499900
Product name: Etofenamate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: e2499900
Price: $150
Updated: 2024/03/01

TCI Chemical

Product number: E1551
Product name: Etofenamate
Purity: min. 98.0 %
Packaging: 250MG
Price: $300
Updated: 2025/07/31

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Etofenamate Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Oil

Originator

Rheumon,Troponwerke,W. Germany,1977

Uses

As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.

Definition

ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.

Manufacturing Process

16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.

Therapeutic Function

Antiinflammatory

Etofenamate Preparation Products And Raw materials

Raw materials

Preparation Products

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Etofenamate Suppliers

Canada 1 China 132 France 1 Germany 3 India 6 South Korea 1 Spain 2 United States 17 Global 163

Shaoxing Hongda Medical Technology Co.,Ltd

Tel: 18072995930
Email: sales001@hongdabova.com
Country: China
ProdList: 25
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Zhejiang Qiming Pharmaceutical Co., Ltd.

Tel: +86-571-87163895 +86-571-87163893
Fax: +86-571-87163816
Email: sales@qimingpharm.com
Country: China
ProdList: 87
Advantage: 65

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2766
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4496
Advantage: 50

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

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View Lastest Price from Etofenamate manufacturers

Dideu Industries Group Limited

Product: Etofenamate 30544-47-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-15

Career Henan Chemical Co

Product: Etofenamate 30544-47-9
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

30544-47-9, EtofenamateRelated Search:

Etomidate 3-Diethylaminophenol Benzyl benzoate FLURBIPROFEN AXETIL Denatonium Benzoate Anhydrous Ethyl acetate 2'-Hydroxy-3-phenylpropiophenone 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Meclofenoxate hydrochloride Ethanol Phenetidine Sodium benzoate Ethyl acrylate Butylparaben Ethylparaben ISOXADIFEN-ETHYL 3-Hydroxybenzoic acid Salicylic acid

EtofenamateEtofenamate

2-(2-hydroxyaethoxy)aethylester der flutenaminsaeure

2-(2-hydroxyethoxy)ethyl-n-(alpha,alpha,alpha-trifluoro-m-tolyl)anthrani late

Benzoic acid, 2[[3-(trifluoromethyl)phenyl]amino]-2-(hydroxyethoxy)ethyl ester

n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilic acid 2-(2-hydroxyethoxy)

2-(2-Hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate

Ethofenamate

Rheumon

Etofenamate

2-(2-Hydroxyethoxy)ethyl FufenaMate

2-[[3-(TrifluoroMethyl)phenyl]aMino]benzoic Acid 2-(2-Hydroxyethoxy)ethyl Ester

Bayrogel

ReuMon

TrauMon Gel

2-(2-hydroxyethoxy)ethyl 2-((3-(trifluoroMethyl)phenyl)aMino)benzoate

EtofenaMate,TV-485

TV-485

TVX-485

Etofenamate, >=98%

CS-1431

Etofenamate CRS

Etofenamate for peak identification CRS

Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(2-hydroxyethoxy)ethyl ester

Etofenamate USP/EP/BP

Etofenate

Etofenamate, 10 mM in DMSO

30544-47-9

Inhibitors

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals